Designing a therapeutic and prophylactic candidate vaccine against human papillomavirus through vaccinomics approaches

A Phase I trial assessing the safety and tolerability of a therapeutic DNA vaccination against HPV16 and HPV18 E6/E7 oncogenes after chemoradiation for cervical cancer

(2020) Yasmin Hasan et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Combined prophylactic and therapeutic immune responses against human papillomaviruses induced by a thioredoxin-based L2-E7 nanoparticle vaccine

(2020) Xueer Zhao et al.   PLoS Pathogens

Bacterial Protein Toll-Like-Receptor Agonists: A Novel Perspective on Vaccine Adjuvants

(2019) Sudeep Kumar et al.   Frontiers in Immunology

Production and Preliminary in vivo Evaluations of a Novel in silico-Designed L2-based Potential HPV Vaccine

(2019) Manica Negahdaripour et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Structural vaccinology considerations for in silico designing of a multi-epitope vaccine

(2018) Manica Negahdaripour et al.   INFECTION GENETICS AND EVOLUTION

Immunoinformatics-aided design of a potential multi-epitope peptide vaccine against Leishmania infantum

(2018) Bahareh Vakili et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The use of databases, data mining and immunoinformatics in vaccinology: where are we?

(2017) Nagendra R. Hegde et al.   Expert Opinion on Drug Discovery

A novel HPV prophylactic peptide vaccine, designed by immunoinformatics and structural vaccinology approaches

(2017) Manica Negahdaripour et al.   INFECTION GENETICS AND EVOLUTION

The ClusPro web server for protein–protein docking

(2017) Dima Kozakov et al.   Nature Protocols

Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization

(2017) Carmen L. Krüger et al.   Science Signaling

Developments in L2-based human papillomavirus (HPV) vaccines

(2017) Christina Schellenbacher et al.   VIRUS RESEARCH

New findings of Toll-like receptors involved in Mycobacterium tuberculosis infection

(2017) Majid Faridgohar et al.   Pathogens and Global Health

Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization

(2017) Carmen L. Krüger et al.   Science Signaling

Toll-Like Receptor Ligand-Based Vaccine Adjuvants Require Intact MyD88 Signaling in Antigen-Presenting Cells for Germinal Center Formation and Antibody Production

(2017) Munir M. Mosaheb et al.   Frontiers in Immunology

Gardasil-9: A global survey of projected efficacy

(2016) Lukai Zhai et al.   ANTIVIRAL RESEARCH

Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response

(2016) M. I. E. van Poelgeest et al.   CLINICAL CANCER RESEARCH

The science of vaccine adjuvants: advances in TLR4 ligand adjuvants

(2016) Steven G Reed et al.   CURRENT OPINION IN IMMUNOLOGY

Progress and prospects for L2-based human papillomavirus vaccines

(2016) Rosie T Jiang et al.   Expert Review of Vaccines

Computational Approaches to Toll-Like Receptor 4 Modulation

(2016) Jean-Marc Billod et al.   MOLECULES

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mycobacterium tuberculosisRpfE promotes simultaneous Th1- and Th17-type T-cell immunity via TLR4-dependent maturation of dendritic cells

(2015) Han-Gyu Choi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An overview of bioinformatics tools for epitope prediction: Implications on vaccine development

(2015) Ruth E. Soria-Guerra et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Human papillomavirus molecular biology and disease association

(2015) John Doorbar et al.   REVIEWS IN MEDICAL VIROLOGY

Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine

(2015) Liliane Maria Fernandes de Oliveira et al.   PLoS One

Immunoprevention of Human Papillomavirus-Associated Malignancies

(2014) J. W. Wang et al.   Cancer Prevention Research

Primary Strategies for HPV Infection and Cervical Cancer Prevention

(2014) DIANE M. HARPER et al.   CLINICAL OBSTETRICS AND GYNECOLOGY

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Raising Expectations For Subunit Vaccine

(2014) John T. Schiller et al.   JOURNAL OF INFECTIOUS DISEASES

AllerTOP v.2—a server for in silico prediction of allergens

(2014) Ivan Dimitrov et al.   JOURNAL OF MOLECULAR MODELING

Low doses of flagellin-L2 multimer vaccines protect against challenge with diverse papillomavirus genotypes

(2014) Kirill Kalnin et al.   VACCINE

Second-generation prophylactic HPV vaccines: successes and challenges

(2013) Mitchell Tyler et al.   Expert Review of Vaccines

Efficacy of RG1-VLP Vaccination against Infections with Genital and Cutaneous Human Papillomaviruses

(2013) Christina Schellenbacher et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mycobacterium tuberculosis RpfB drives Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells

(2013) Jong-Seok Kim et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Optimization of Multimeric Human Papillomavirus L2 Vaccines

(2013) Subhashini Jagu et al.   PLoS One

Fusion protein linkers: Property, design and functionality

(2012) Xiaoying Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

GalaxyTBM: template-based modeling by building a reliable core and refining unreliable local regions

(2012) Junsu Ko et al.   BMC BIOINFORMATICS

Immune epitope database analysis resource

(2012) Y. Kim et al.   NUCLEIC ACIDS RESEARCH

GalaxyWEB server for protein structure prediction and refinement

(2012) J. Ko et al.   NUCLEIC ACIDS RESEARCH

Reliable B Cell Epitope Predictions: Impacts of Method Development and Improved Benchmarking

(2012) Jens Vindahl Kringelum et al.   PLoS Computational Biology

A multimeric L2 vaccine for prevention of animal papillomavirus infections

(2011) Subhashini Jagu et al.   VIROLOGY

High-throughput prediction of protein antigenicity using protein microarray data

(2010) Christophe N. Magnan et al.   BIOINFORMATICS

Cervical Human Papillomavirus Prevalence in 5 Continents: Meta‐Analysis of 1 Million Women with Normal Cytological Findings

(2010) Laia Bruni et al.   JOURNAL OF INFECTIOUS DISEASES

Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins

(2009) Susan Carpenter et al.   BIOCHEMICAL JOURNAL

SOLpro: accurate sequence-based prediction of protein solubility

(2009) Christophe N. Magnan et al.   BIOINFORMATICS

Currently approved prophylactic HPV vaccines

(2009) Diane M Harper   Expert Review of Vaccines

Papillomavirus Prophylactic Vaccines: Established Successes, New Approaches

(2009) M. S. Campo et al.   JOURNAL OF VIROLOGY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Phase I Immunotherapeutic Trial with Long Peptides Spanning the E6 and E7 Sequences of High-Risk Human Papillomavirus 16 in End-Stage Cervical Cancer Patients Shows Low Toxicity and Robust Immunogenicity

(2008) G. G. Kenter et al.   CLINICAL CANCER RESEARCH

NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8–11

(2008) Claus Lundegaard et al.   NUCLEIC ACIDS RESEARCH