Toll-Like Receptor Ligand-Based Vaccine Adjuvants Require Intact MyD88 Signaling in Antigen-Presenting Cells for Germinal Center Formation and Antibody Production

Vaccine Adjuvant MF59 Promotes Retention of Unprocessed Antigen in Lymph Node Macrophage Compartments and Follicular Dendritic Cells

(2015) Rocco Cantisani et al.   JOURNAL OF IMMUNOLOGY

B-cell-intrinsic STAT6 signaling controls germinal center formation

(2014) Adriana Turqueti-Neves et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-like receptor 9 signaling acts on multiple elements of the germinal center to enhance antibody responses

(2014) D. C. Rookhuizen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immunity and Vaccines

(2013) Andrew Platt et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Requirement for MyD88 Signaling in B Cells and Dendritic Cells for Germinal Center Anti-Nuclear Antibody Production in Lyn-Deficient Mice

(2013) Z. Hua et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Macrophages Are Required for Localization of Antigen-Activated B Cells to the Follicular Perimeter and the Subsequent Germinal Center Response

(2013) N. Nikbakht et al.   JOURNAL OF IMMUNOLOGY

In Vivo and In Vitro Characterization of the Immune Stimulating Activity of the Neisserial Porin PorB

(2013) Andrew Platt et al.   PLoS One

Modulating the innate immune response by combinatorial engineering of endotoxin

(2013) Brittany D. Needham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CpG ODN and ISCOMATRIX Adjuvant: A Synergistic Adjuvant Combination Inducing Strong T-Cell IFN-γResponses

(2013) Michael J. McCluskie et al.   Biomed Research International

Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine adjuvants

(2012) Colleen Olive   Expert Review of Vaccines

Contribution of Toll-like receptor signaling to germinal center antibody responses

(2012) Anthony L. DeFranco et al.   IMMUNOLOGICAL REVIEWS

The Importance of Adjuvant Formulation in the Development of a Tuberculosis Vaccine

(2012) S. L. Baldwin et al.   JOURNAL OF IMMUNOLOGY

MyD88: A Critical Adaptor Protein in Innate Immunity Signal Transduction

(2012) N. Warner et al.   JOURNAL OF IMMUNOLOGY

Lymph Node Macrophages

(2012) Elizabeth E. Gray et al.   Journal of Innate Immunity

MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

(2012) Namiko Hoshi et al.   Nature Communications

Selective Utilization of Toll-like Receptor and MyD88 Signaling in B Cells for Enhancement of the Antiviral Germinal Center Response

(2011) Baidong Hou et al.   IMMUNITY

MyD88 Plays an Essential Role in Inducing B Cells Capable of Differentiating into Antibody-Secreting Cells after Vaccination

(2011) S.-M. Kang et al.   JOURNAL OF VIROLOGY

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

(2011) A. Seubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting TLRs Expands the Antibody Repertoire in Response to a Malaria Vaccine

(2011) S. R. Wiley et al.   Science Translational Medicine

Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes

(2011) Samuele Calabro et al.   VACCINE

Toll-like Receptor 7 Controls the Anti-Retroviral Germinal Center Response

(2011) Edward P. Browne   PLoS Pathogens

Innate immune function of the neisserial porins and the relationship to vaccine adjuvant activity

(2010) Lee M Wetzler   Future Microbiology

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

B Cell Intrinsic MyD88 Signals Drive IFN-  Production from T Cells and Control Switching to IgG2c

(2009) T. A. Barr et al.   JOURNAL OF IMMUNOLOGY

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

(2009) S. Z. Ben-Sasson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms

(2008) Baidong Hou et al.   IMMUNITY

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

(2008) Mirjam Kool et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular and cellular signatures of human vaccine adjuvants

(2008) F. Mosca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant

(2008) Xiuping Liu et al.   VACCINE