Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells

Thymic development of gut-microbiota-specific T cells

(2021) Daniel F. Zegarra-Ruiz et al.   NATURE

Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation

(2021) Wenqiang Li et al.   Brain and Behavior

An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint

(2020) Deepshika Ramanan et al.   CELL

Microbial–host molecular exchange and its functional consequences in early mammalian life

(2020) Stephanie C. Ganal-Vonarburg et al.   SCIENCE

Variations in microbiota composition of laboratory mice influence Citrobacter rodentium infection via variable short-chain fatty acid production

(2020) Lisa Osbelt et al.   PLoS Pathogens

TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity

(2020) Stacey N. Harbour et al.   Science Immunology

Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study

(2020) Katri Korpela et al.   CELL

Maternal immune activation in mice disrupts proteostasis in the fetal brain

(2020) Brian T. Kalish et al.   NATURE NEUROSCIENCE

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

Maternal IgA protects against the development of necrotizing enterocolitis in preterm infants

(2019) Kathyayini P. Gopalakrishna et al.   NATURE MEDICINE

Maternal Vertical Transmission Affecting Early-life Microbiota Development

(2019) Shaopu Wang et al.   TRENDS IN MICROBIOLOGY

IL-17a promotes sociability in mouse models of neurodevelopmental disorders

(2019) Michael Douglas Reed et al.   NATURE

Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome

(2018) Pamela Ferretti et al.   Cell Host & Microbe

Cutting Edge: Critical Roles for Microbiota-Mediated Regulation of the Immune System in a Prenatal Immune Activation Model of Autism

(2018) Catherine R. Lammert et al.   JOURNAL OF IMMUNOLOGY

NGmerge: merging paired-end reads via novel empirically-derived models of sequencing errors

(2018) John M. Gaspar   BMC BIOINFORMATICS

Citrobacter rodentium: a model enteropathogen for understanding the interplay of innate and adaptive components of type 3 immunity

(2017) D J Silberger et al.   Mucosal Immunology

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring

(2017) Sangdoo Kim et al.   NATURE

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes

(2017) Maximilian Witzel et al.   NATURE GENETICS

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Development of a real-time PCR assay for quantification of Citrobacter rodentium

(2016) Sofia Sagaidak et al.   JOURNAL OF MICROBIOLOGICAL METHODS

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin

(2016) Ballachanda N Devaiah et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

The maternal microbiota drives early postnatal innate immune development

(2016) M. Gomez de Aguero et al.   SCIENCE

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

(2016) G. B. Choi et al.   SCIENCE

How colonization by microbiota in early life shapes the immune system

(2016) Thomas Gensollen et al.   SCIENCE

BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin

(2016) Ballachanda N Devaiah et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Epigenetics and the Developmental Origins of Inflammatory Bowel Diseases

(2016) Richard Kellermayer   CANADIAN JOURNAL OF GASTROENTEROLOGY

Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders

(2015) Brian K. Lee et al.   BRAIN BEHAVIOR AND IMMUNITY

Evidence supporting an altered immune response in ASD

(2015) Jennifer Mead et al.   IMMUNOLOGY LETTERS

Citrobacter rodentium -induced colitis: A robust model to study mucosal immune responses in the gut

(2015) Ekaterina P. Koroleva et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria

(2015) D Rios et al.   Mucosal Immunology

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Gastrointestinal Issues in Autism Spectrum Disorder

(2014) Elaine Y Hsiao   HARVARD REVIEW OF PSYCHIATRY

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism

(2012) Natalia V. Malkova et al.   BRAIN BEHAVIOR AND IMMUNITY

The Transcription Factors Thpok and LRF Are Necessary and Partly Redundant for T Helper Cell Differentiation

(2012) Andrea C. Carpenter et al.   IMMUNITY

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies

(2012) Anna Klindworth et al.   NUCLEIC ACIDS RESEARCH

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Gastrointestinal Conditions in Children With Autism Spectrum Disorder: Developing a Research Agenda

(2012) Daniel L. Coury et al.   PEDIATRICS

The Co-Morbidity Burden of Children and Young Adults with Autism Spectrum Disorders

(2012) Isaac S. Kohane et al.   PLoS One

Modeling an autism risk factor in mice leads to permanent immune dysregulation

(2012) E. Y. Hsiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to ExacerbatedCitrobacter rodentium-Induced Colitis

(2011) M. Wlodarska et al.   INFECTION AND IMMUNITY

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report

(2010) Timothy Buie et al.   PEDIATRICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Developmental Origins of Health and Disease: Brief History of the Approach and Current Focus on Epigenetic Mechanisms

(2009) Pathik Wadhwa et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Supplementation with Lactobacillus rhamnosus or Bifidobacterium lactis probiotics in pregnancy increases cord blood interferon-γ and breast milk transforming growth factor-β and immunoglobin A detection

(2008) S. L. Prescott et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Effect of In Utero and Early-Life Conditions on Adult Health and Disease

(2008) Peter D. Gluckman et al.   NEW ENGLAND JOURNAL OF MEDICINE