Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study

SLC6A14 deficiency is linked to obesity, fatty liver, and metabolic syndrome but only under conditions of a high-fat diet

(2021) Sathish Sivaprakasam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice

(2021) Hyo Shin Yoon et al.   Nature Microbiology

SLIM: Simultaneous Logic-in-Memory Computing Exploiting Bilayer Analog OxRAM Devices

(2020) Sandeep Kaur Kingra et al.   Scientific Reports

Ileo-colonic delivery of conjugated bile acids improves glucose homeostasis via colonic GLP-1-producing enteroendocrine cells in human obesity and diabetes

(2020) Gerardo Calderon et al.   EBioMedicine

Treatment with Anaerobutyricum soehngenii: a pilot study of safety and dose–response effects on glucose metabolism in human subjects with metabolic syndrome

(2020) Pim W. Gilijamse et al.   npj Biofilms and Microbiomes

Simplified Intestinal Microbiota to Study Microbe-Diet-Host Interactions in a Mouse Model

(2019) Petia Kovatcheva-Datchary et al.   Cell Reports

Differential effects of a 40 hour fast and bile acid supplementation on human GLP-1 and FGF19 responses.

(2019) F. Samuel Van Nierop et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Targeting the Enteric Nervous System to Treat Metabolic Disorders? “Enterosynes” as Therapeutic Gut Factors

(2019) Claude Knauf et al.   NEUROENDOCRINOLOGY

Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition

(2019) Louise B. Thingholm et al.   Cell Host & Microbe

Three-dimensional Epigenome Statistical Model: Genome-wide Chromatin Looping Prediction

(2018) Ziad Al Bkhetan et al.   Scientific Reports

Additive Dose Response Models: Explicit Formulation and the Loewe Additivity Consistency Condition

(2018) Simone Lederer et al.   Frontiers in Pharmacology

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects

(2018) KEC Bouter et al.   Clinical and Translational Gastroenterology

Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas

(2018) Rune E. Kuhre et al.   Molecular Metabolism

MC4R-dependent suppression of appetite by bone-derived lipocalin 2

(2017) Ioanna Mosialou et al.   NATURE

Classification of different degrees of adiposity in sedentary rats

(2016) A.S. Leopoldo et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Bacterial Communities: Interactions to Scale

(2016) Reed M. Stubbendieck et al.   Frontiers in Microbiology

Microbial regulation of GLP-1 and L-cell biology

(2016) Thomas U. Greiner et al.   Molecular Metabolism

Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice

(2016) Shanthadevi Udayappan et al.   npj Biofilms and Microbiomes

Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

(2015) Cheryl A. Brighton et al.   ENDOCRINOLOGY

Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms

(2015) Gerardo Cárcamo-Oyarce et al.   Nature Communications

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

(2015) Changtao Jiang et al.   Nature Communications

REG1B as a predictor of childhood stunting in Bangladesh and Peru

(2013) Kristine M Peterson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation

(2013) Atle van Beelen Granlund et al.   CELL AND TISSUE RESEARCH

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Incretin secretion stimulated by ursodeoxycholic acid in healthy subjects

(2013) Masanori Murakami et al.   SpringerPlus

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

Pancreatic islet-specific overexpression of Reg3β protein induced the expression of pro-islet genes and protected the mice against streptozotocin-induced diabetes mellitus

(2011) Xiaoquan Xiong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Expression Profile of the REG Gene Family in Colorectal Carcinoma

(2011) Hua-chuan Zheng et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Lipocalin-2 Deficiency Impairs Thermogenesis and Potentiates Diet-Induced Insulin Resistance in Mice

(2010) H. Guo et al.   DIABETES

Human faecal microbiota display variable patterns of glycerol metabolism

(2010) Rosemarie De Weirdt et al.   FEMS MICROBIOLOGY ECOLOGY

Evaluation of the Intestinal Colonization by Microencapsulated Probiotic Bacteria in Comparison With the Same Uncoated Strains

(2010) Mario Del Piano et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-transferase gene

(2009) Petra Louis et al.   ENVIRONMENTAL MICROBIOLOGY

Overexpression of Reg3α increases cell growth and the levels of cyclin D1 and CDK4 in insulinoma cells

(2009) Wei Cui et al.   GROWTH FACTORS

Differential NF- B pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance

(2009) P. van Baarlen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA