N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer

Colorectal cancer statistics, 2020

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YTHDF 1‐mediated translation amplifies Wnt‐driven intestinal stemness

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m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer

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Increased expression of GEF-H1 promotes colon cancer progression by RhoA signaling

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The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression

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Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells

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Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

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Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities

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Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

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YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma

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MAP9 loss triggers chromosomal instability, initiates colorectal tumorigenesis and is associated with poor survival of colorectal cancer patients

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The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

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Colorectal cancer liver metastases – a population-based study on incidence, management and survival

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Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

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An additional class of m6A readers

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Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility

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Refined RIP-seq protocol for epitranscriptome analysis with low input materials

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m6A facilitates hippocampus-dependent learning and memory through YTHDF1

(2018) Hailing Shi et al.   NATURE

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity

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MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity

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Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine

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Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth

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N6-methyladenosine Modulates Messenger RNA Translation Efficiency

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Movers and shakers: cell cytoskeleton in cancer metastasis

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The RhoGEF GEF-H1 Is Required for Oncogenic RAS Signaling via KSR-1

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The Liver-First Approach to the Management of Colorectal Cancer With Synchronous Hepatic Metastases

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Comprehensive molecular characterization of human colon and rectal cancer

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Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

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siRNA-optimized Modifications for Enhanced In Vivo Activity

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GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

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International network of cancer genome projects

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Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?

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