Hydroxysafflor yellow A and anhydrosafflor yellow B alleviate ferroptosis and parthanatos in PC12 cells injured by OGD/R

MYCN-amplified neuroblastoma is addicted to iron and vulnerable to inhibition of the system Xc-/glutathione axis

(2021) Konstantinos V. Floros et al.   CANCER RESEARCH

Cellular degradation systems in ferroptosis

(2021) Xin Chen et al.   CELL DEATH AND DIFFERENTIATION

p53 Promoted Ferroptosis in Ovarian Cancer Cells Treated with Human Serum Incubated-Superparamagnetic Iron Oxides

(2021) Yunhan Zhang et al.   International Journal of Nanomedicine

Mutant NMNAT1 leads to a retina-specific decrease of NAD+ accompanied by increased poly(ADP-ribose) in a mouse model of NMNAT1-associated retinal degeneration

(2021) Scott H Greenwald et al.   HUMAN MOLECULAR GENETICS

mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation

(2021) Yilei Zhang et al.   Nature Communications

Oxidative stress and regulated cell death in Parkinson’s disease

(2021) P.A. Dionísio et al.   AGEING RESEARCH REVIEWS

Enoyl coenzyme A hydratase 1 alleviates nonalcoholic steatohepatitis in mice by suppressing hepatic ferroptosis

(2021) Bing Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome

(2021) Ofer Beharier et al.   PLACENTA

Cerebral oxygen metabolism in adults with sickle cell disease

(2020) Lena Václavů et al.   AMERICAN JOURNAL OF HEMATOLOGY

Three Ingredients of Safflower Alleviate Acute Lung Injury and Inhibit NET Release Induced by Lipopolysaccharide

(2020) Yun-peng Wang et al.   MEDIATORS OF INFLAMMATION

Baicalein attenuates caspase-independent cells death via inhibiting PARP-1 activation and AIF nuclear translocation in cerebral ischemia/reperfusion rats

(2020) Wei-Han Li et al.   APOPTOSIS

Simultaneous Optimization of the Ultrasonic Extraction Method and Determination of the Antioxidant Activities of Hydroxysafflor Yellow A and Anhydrosafflor Yellow B from Safflower Using a Response Surface Methodology

(2020) Yangyang Zhang et al.   MOLECULES

Induction of ferroptosis in response to graphene quantum dots through mitochondrial oxidative stress in microglia

(2020) Tianshu Wu et al.   Particle and Fibre Toxicology

Response surface optimization of the water immersion extraction and macroporous resin purification processes of anhydrosafflor yellow B from Carthamus tinctorius L. 

(2020) Peng Zhou et al.   JOURNAL OF FOOD SCIENCE

Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function

(2020) Andy W. C. Man et al.   Oxidative Medicine and Cellular Longevity

Hydroxysafflor Yellow A Exerts Anti-Inflammatory Effects Mediated by SIRT1 in Lipopolysaccharide-Induced Microglia Activation

(2020) Xiude Qin et al.   Frontiers in Pharmacology

Therapeutic Potential of Hydroxysafflor Yellow A on Cardio-Cerebrovascular Diseases

(2020) Xue Bai et al.   Frontiers in Pharmacology

Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms

(2020) Lulu Sun et al.   DNA AND CELL BIOLOGY

Galangin attenuated cerebral ischemia-reperfusion injury by inhibition of ferroptosis through activating the SLC7A11/GPX4 axis in gerbils

(2020) Xue Guan et al.   LIFE SCIENCES

Ferritin reduction is essential for cerebral ischemia-induced hippocampal neuronal death through p53/SLC7A11-mediated ferroptosis

(2020) Wei Chen et al.   BRAIN RESEARCH

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

(2019) Ishraq Alim et al.   CELL

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Inhibition of double-stranded RNA-dependent protein kinase prevents oxytosis and ferroptosis in mouse hippocampal HT22 cells

(2019) Yoko Hirata et al.   TOXICOLOGY

Global brain inflammation in stroke

(2019) Kaibin Shi et al.   LANCET NEUROLOGY

UPLC-QTOF/MS-Based Metabolomics Reveals the Protective Mechanism of Hydrogen on Mice with Ischemic Stroke

(2019) Lilin Chen et al.   NEUROCHEMICAL RESEARCH

Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro

(2019) Takujiro Homma et al.   EXPERIMENTAL CELL RESEARCH

Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury

(2019) Thekla Cordes et al.   Molecular Metabolism

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

The Development of the Concept of Ferroptosis

(2018) Tal Hirschhorn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis 

(2018) Bo Zhou et al.   CELL RESEARCH

Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson’s disease

(2018) Tae-In Kam et al.   SCIENCE

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

The MIFstep in parthanatos

(2016) E. Jonas   SCIENCE

RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death

(2016) Jasmin Dächert et al.   Oncotarget

Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK

(2015) Ying Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Edaravone protected PC12 cells against MPP(+)-cytoxicity via inhibiting oxidative stress and up-regulating heme oxygenase-1 expression

(2014) Baohua Cheng et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Protective Effects of Hydroxysafflor Yellow A on β-Amyloid-Induced Neurotoxicity in PC12 Cells

(2013) Song-Zhi Kong et al.   NEUROCHEMICAL RESEARCH

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Deletion of the ageing gene p66Shc reduces early stroke size following ischaemia/reperfusion brain injury

(2012) Remo D. Spescha et al.   EUROPEAN HEART JOURNAL

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Transient Protection from Heat-Stress Induced Apoptotic Stimulation by Metastasis-Associated Protein 1 in Pachytene Spermatocytes

(2011) Wei Li et al.   PLoS One

Mitochondrial and Nuclear Cross Talk in Cell Death

(2010) Shaida A. Andrabi et al.   Annals of the New York Academy of Sciences

Mitochondria, oxidative metabolism and cell death in stroke

(2009) Neil R. Sims et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Parthanatos, a messenger of death

(2009) Karen Kate David   Frontiers in Bioscience-Landmark

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

(2009) C. L. Allen et al.   International Journal of Stroke

Nicotinamide Rescues Human Embryonic Stem Cell-Derived Neuroectoderm from Parthanatic Cell Death

(2009) Flavio Cimadamore et al.   STEM CELLS

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

Qualitative evaluation and quantitative determination of 10 major active components in Carthamus tinctorius L. by high-performance liquid chromatography coupled with diode array detector

(2008) Li Fan et al.   JOURNAL OF CHROMATOGRAPHY A