Optimization of microwave assisted extraction of Artocarpus Heterophyllus leaf polyphenols with inhibitory action against Alternaria sp. and antioxidant capacity

The Artocarpus heterophyllus extracts are receiving attention due to their agro-food applications. Then, the simultaneous optimization of microwave-assisted extraction of polyphenols from jackfruit leaf with growth inhibitory action against Alternaria sp. was studied. The effects of power and time on total soluble polyphenols and total flavonoids contents, and antifungal activity were investigated using response surface methodology. Temperature behavior was considered also. Models showed good prediction and successfully validation. Treatment at 840 W and 2 min allowed the responses maximization (148.75 mg galic acid equivalent /g dried weight of total soluble polyphenols, 13.28 mg rutin equivalent /g dried weight of total flavonoids, and 39.9% of antifungal activity). Furthermore, high ABTS(+) (97%) and DPPH (92%) inhibition was exhibited, as a function of the polyphenol's concentration and composition. Mainly flavonoids with potential antioxidant and antifungal properties were detected. These findings suggest the potentialities of these extracts for Alternaria sp. control during tomato postharvest.

Automated summary

Microwave-assisted extraction of polyphenols from jackfruit leaves with growth inhibitory action against Alternaria sp. was optimized with good results. The optimal conditions of 840 W and 2 minutes showed the highest polyphenol content and antifungal activity. The extracts exhibited high antioxidant and antifungal properties, suggesting their potential for controlling Alternaria sp. during tomato postharvest.