Article
Chemistry, Applied
Sourour Idoudi, Yousef Hijji, Takwa Bedhiafi, Hesham M. Korashy, Shahab Uddin, Maysaloun Merhi, Said Dermime, Nashiru Billa
Summary: In this study, a successful CUR.SA conjugate has been developed and encapsulated in CM nanoparticles, showing favorable attributes for further anti-colon cancer research.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Yuan Gao, Xiaochen Gong, Shuang Yu, Zheng Jin, Qicheng Ruan, Chunjing Zhang, Kai Zhao
Summary: The study found that N-2-Hydroxypropyl trimethyl ammonium chloride chitosan/N, O-carboxymethyl chitosan nanoparticles (N-2-HACC/CMCS NPs) showed good immunogenicity and no toxicity as a universal vaccine adjuvant/delivery system. The prepared N-2-HACC/OVA/CMCS NPs induced higher levels of antibodies and immune responses in mice, suggesting their potential in enhancing humoral, cellular, and mucosal immune responses.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Lingyu Han, Ruiyi Zhai, Bing Hu, Jixin Yang, Yaoyao Li, Zhe Xu, Yueyue Meng, Tingting Li
Summary: The synthesis and characterization of octenyl-succinylated chitosan with different degrees of substitution were investigated. The self-assembly behavior of the modified chitosan oligosaccharide in solution was evaluated. The antimicrobial activity and emulsion stability of the modified product were also studied, showing potential applications in encapsulation and delivery.
Article
Biochemistry & Molecular Biology
Xuepeng Yu, Yueyue Yang, Qing Liu, Zhengyu Jin, Aiquan Jiao
Summary: CEO-loaded chitosan nanoparticles (CNs) were prepared and embedded in HPMC/HPS blends to improve the properties of the formed films. The reinforced nanocomposite films showed enhanced mechanical and barrier properties, as well as sustained release of CEO with antioxidant and antimicrobial effects. These nanocomposite films have great potential for food preservation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Sourour Idoudi, Takwa Bedhiafi, Fairooz Sahir, Yousef Hijji, Shahab Uddin, Maysaloun Merhi, Said Dermime, Nashiru Billa
Summary: This study evaluated the anti-cancer activity of curcumin nanoparticles (CUR-NPs) and succinylated curcumin nanoparticles (CUR.SA-NPs) on colon cancer cell lines. The nanoparticles showed dose and time-dependent cytotoxicity, inducing apoptosis through activation of Caspase signaling. Based on their promising attributes and in vitro results, further investigation into the role of these nanoparticle formulations in CRC management is warranted.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Ling Ding, Zhao Liu, Shen Song, Mohamed Aamer Abubaker, Lele Chen, Jipeng Shi, Zengjie Fan, Ji Zhang
Summary: HACC, synthesized by reacting chitosan with glycidyl trimethylammonium chloride, forms a non-Newtonian pseudoplastic fluid in solution, with thixotropy highly dependent on concentration changes. Dynamic viscoelasticity tests show that HACC exhibits both viscous behavior similar to a fluid and elastic properties of weak gel.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Juliana Domingues dos Santos Carvalho, Renata Santos Rabelo, Miriam Dupas Hubinger
Summary: The study investigated the thermal and rheological properties of methylcellulose and hydroxypropyl methylcellulose hydrogels with the addition of chitosan. The results indicated that the addition of chitosan allowed these polymers to form gels at lower temperatures, which could benefit the processing of oil carrier systems under milder thermal conditions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Yang Zhou, Zhenghao Zhai, Yimin Yao, John C. Stant, Sarah L. Landrum, Michael J. Bortner, Charles E. Frazier, Kevin J. Edgar
Summary: Polysaccharide-based Schiff base hydrogels prepared by reacting oxidized hydroxypropyl cellulose (Ox-HPC) with carboxymethyl chitosan (CMCS) exhibit pH-responsive, injectable, and self-healing properties. The reversible nature of the imine bonds allows for an injectable and self-healing hydrogel. The incorporation of the model amine-containing drug phenylalanine within the hydrogel showed pH sensitivity, releasing faster in the extracellular space around tumors (pH 6.8) compared to normal tissues (pH 7.4).
CARBOHYDRATE POLYMERS
(2023)
Article
Biochemistry & Molecular Biology
Jinwen Liu, Shuyan Li, Wuliji Ao, Yongji Li, Yingge Xiao, Meirong Bai
Summary: This study aimed to improve the permeability and solubility of aprepitant to enhance its oral bioavailability. Hydroxypropyl chitosan was used as a stabilizer for the nanosuspension, resulting in a higher solubility compared to aprepitant. The nanosuspension also showed improved permeability in Caco-2 cells.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Jae Seo Lee, Hyo-Sung Kim, Haram Nah, Sang Jin Lee, Ho-Jin Moon, Jae Beum Bang, Jung Bok Lee, Sun Hee Do, Il Keun Kwon, Dong Nyoung Heo
Summary: This study synthesized succinylated chitosan (SCS)-based hydrogels with high decomposition rate and excellent biocompatibility, confirming well distributed Bone Graft Materials (BGMs) inside the SCS hydrogel. Increasing succinylation rate in SCS-B hydrogels led to a decrease in mechanical properties, such as compressive strength and Young's modulus, while also exhibiting high cell growth rate and bone differentiation rate. In vivo results showed that the SCS hydrogel could resorb into surrounding tissues while maintaining BGMs in the transplantation area for up to 6 weeks, indicating potential as a bioactive drug carrier for various biomedical applications.
Article
Biochemistry & Molecular Biology
Lin Yue, Min Wang, Imran Mahmood Khan, Jianguo Xu, Chifang Peng, Zhouping Wang
Summary: In this study, cinnamic acid conjugated hydroxypropyl chitosan derivatives with different degrees of substitution were successfully synthesized and showed good antibacterial activity against Staphylococcus aureus and Escherichia coli. The derivatives exhibited better water solubility than chitosan and had a significant inhibitory effect on biofilm formation. These results suggest the potential applicability of these derivatives in the treatment of biofilm-associated infections.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Jilong Cao, Guanghua He, Xiaoqing Ning, Cheng Wang, Lihong Fan, Yihua Yin, Weiquan Cai
Summary: A facile approach was developed for the preparation of dual self-healing and adsorption hydrogel through HPCS, PAM, and PVA. The hydrogel exhibited high adsorption capacity and mechanical strength, making it a promising candidate for long-life adsorbents.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Chun Lam Clement Chan, Iek Man Lei, Gea T. van de Kerkhof, Richard M. Parker, Kieran D. Richards, Rachel C. Evans, Yan Yan Shery Huang, Silvia Vignolini
Summary: This study combines cholesteric hydroxypropyl cellulose with in situ photo-crosslinking to produce filaments with an internal helicoidal nanoarchitecture, enabling the direct ink writing of solid, volumetric objects with structural color. By tuning the lyotropic or thermotropic behavior of the cellulose, the iridescent color of the objects can be adjusted across the visible spectrum, allowing for the printing of objects with different colors from the same feedstock.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Engineering, Chemical
Nan Li, Zhi Wang, Jixiao Wang
Summary: Carbonic anhydrase (CA)-inspired membranes were developed by incorporating hydroxypropyl-beta-cyclodextrins (H beta-CDs) into polyamide networks. The hydrophobic inner cavities of H beta-CDs mimic the hydrophobic pockets of CA enzymes. The introduction of H beta-CDs enhances the transport of CO2 molecules and polar components, making these membranes suitable for CO2 separation.
JOURNAL OF MEMBRANE SCIENCE
(2023)
Article
Multidisciplinary Sciences
Hyunwoo Son, Sun-Je Kim, Jongwoo Hong, Jangwoon Sung, Byoungho Lee
Summary: Colorimetric sensing is a promising technique for detecting bio-molecular signals with the naked eye. All-dielectric nanostructures have the potential for distinct color variations, but their sensitivity to environmental changes is limited. To overcome this, a dual-resonance all-dielectric metasurface colorimetric sensor was proposed, and advanced optimization techniques using deep neural networks were used to improve sensing performance and design efficiency.
SCIENTIFIC REPORTS
(2022)
Article
Food Science & Technology
Ewelina Bigoraj, Iwona Kozyra, Agnieszka Kaupke, Zbigniew Osinski, James Lowther, Artur Rzezutka
Summary: The aim of this study was to assess the prevalence of human enteric viruses in mussels sold on the Polish market and study the fecal contamination of shellfish. The study found that human enteric viruses were commonly present in shellfish, with norovirus being the most frequently detected. The study also observed a seasonal distribution pattern of viruses in shellfish samples.
Editorial Material
Food Science & Technology
Bojan Blagojevic, Lis Alban Denmark
Article
Food Science & Technology
Indy Magnus, Fatemeh Abbasi, Hugo Thienpont, Lien Smeesters
Summary: Food safety and quality are increasingly important in our society, driving the development of novel optical food sensing technologies. However, current optical sensing technologies are often limited in their sensitivity and product variability. In this study, we developed a novel pistachio nut screening methodology using fluorescence spectroscopy and advanced chemometrics to simultaneously detect shells, tree parts, and aflatoxins. By optimizing hardware and software parameters, we achieved a high classification accuracy for healthy pistachio kernels.
Article
Food Science & Technology
Xiaodong Wang, Jingqiang Yu, Haixia Wu, Leiying Wu, Wuyunga Borjihan, Cong Wang, Munkhjargal Burenjargal, Alideertu Dong
Summary: This study developed a novel photon-phonon coupling (PPC) cold sterilization technology and compared its effects with low-temperature pasteurization and microwave ultraviolet. The results showed that PPC effectively reduced bacterial count in raw milk with minimal impact on milk quality and nutritional composition.
Review
Food Science & Technology
Riyadh Abdulmalek Hassan, Sharina Abu Hanifah, Lee Yook Heng, Fawaz Al-badaii, Alizar Ulianas
Summary: This study used bibliometric visualisation map analysis to explore the publication outputs, trends, and hotspots for endocrine disruptors (EDMs) biosensor development in relation to mycotoxins. The analysis showed that the current literature primarily focuses on developing biosensors for detecting highly toxic and widely distributed mycotoxins in food, but there needs to be more focus on biosensors for detecting mycotoxins known as endocrine disruptors.
Article
Food Science & Technology
Yajie Zheng, Jianpeng Dou, Changpo Sun, Hujun Liu, Shipei Zhang, Wenfu Wu
Summary: This study investigated the efficiency of modified SA/ll-glucan/Mt microsphere adsorbents in removing DON and ZEN from CSL. The microspheres showed high adsorption capacity, and simple and rapid regeneration was achieved without affecting the removal efficiency of mycotoxins from CSL.
Article
Food Science & Technology
Carlos Adelantado, Jose Angel Salatti-Dorado, Carlos Herrera, Lourdes Arce, Maria Jose Cardador
Summary: High-performance-ion mobility spectrometry (HPIMS) was used for the first time in the analysis of olive oil samples, following a simple liquid-liquid extraction procedure. The developed methodology is user-friendly, fast, and inexpensive, complying with the principles of green chemistry. The proposed approach, combined with multivariate analysis, showed potential in classifying olive oil samples based on their organoleptic quality, with high accuracy rates.
Article
Food Science & Technology
Jia-Wen Wei, Jia-Rong He, Shi-Yi Chen, Yi-Han Guo, Xuan-Zhu Huo, Nuan Zheng, Shuo-Hui Cao, Yao-Qun Li
Summary: Polycyclic aromatic hydrocarbons (PAHs) are a major cause of human cancer. This study developed a quantitative analysis method for PAH4 using the back propagation neural network (BPNN) algorithm and constant wavelength synchronous fluorescence (CWSF) spectra as the data sets. The method can predict the concentrations of PAH4 in edible oil samples without preprocessing or pre-separation. It has been proven to be a powerful tool for the rapid detection of PAH4.
Article
Food Science & Technology
Liyun Chen, Xiumei Li, Jingyi Chen, Ranxun Lin, Yuhan Mai, Yuxin Lin, Guodong Wang, Zheng Chen, Wei Zhang, Jiang Wang, Cai Yuan, Longguang Jiang, Peng Xu, Mingdong Huang
Summary: Food spoilage is primarily caused by microbial contamination. Curcumin has shown moderate antimicrobial activity as a food preservative. This study formulates curcumin with zinc acetate to enhance its efficacy, resulting in Cur-Zn with increased antimicrobial activity against multiple food-contaminating bacteria and fungi. With light illumination, the antimicrobial activity of Cur-Zn is further enhanced due to the photodynamic inactivation (PDI) effect.
Article
Food Science & Technology
Marta Pilar Ortiz-Moriano, Gonzalo Machado-Schiaffino, Eva Garcia-Vazquez, Alba Ardura
Summary: Mislabelling in the global fisheries sector raises concerns about the identity, safety, and sustainability of seafood products. This study examined mislabelling in shrimps and prawns sold in the Spanish market and assessed potential risks of heavy metal ingestion.
Article
Food Science & Technology
Doyeon Kim, Jinwoo Kim, Minsik Kim
Summary: This study demonstrates the enhanced bactericidal activity of engineered lysins fused with amphipathic antimicrobial peptides against Gram-negative bacterium Cronobacter sakazakii. The fusion lysins are capable of disrupting bacterial cells and significantly reducing the risk of infection within a certain range of temperature and pH. Additionally, the study also shows the bactericidal effect of these fusion lysins against other Gram-negative pathogens.
Article
Food Science & Technology
Seul-Ki Park, Kyung-Jin Cho, Du-Min Jo, Young-Mog Kim
Summary: This study presents a new approach for detecting pathogenic Vibrio spp. in contaminated seafood, which combines PCR with a simplified DNA extraction process and pre-culturing step. The method has been validated and shown to be efficient, time-saving, and highly sensitive, offering a potential alternative for improving safety measures in the food industry.
Article
Food Science & Technology
Suwimol Surareungchai, Chaleeda Borompichaichartkul, Chitsiri Rachtanapun, Nutthachai Pongprasert, Pongphen Jitareerat, Varit Srilaong
Summary: This study builds upon previous research and focuses on risk assessment and analysis in the organic salad industry. The results show that previous risk matrix models can be adapted for various raw materials, and preventive control plans can be applied across different aspects of the production process.
Article
Food Science & Technology
Xuan Zhang, Changling Fang, Xiaoyi Lou, Feng Han, Siman Li, Yongfu Shi, Dongmei Huang
Summary: This study aimed to assess the levels of Biogenic amines (BAs) in four common food types in the Chinese market. It was found that cheese and seafood derived product showed higher levels of BAs, and the histamine level in mackerel and yellow rice wine exceeded the limits.
Article
Food Science & Technology
Martina Foschi, Alessandra Biancolillo, Federico Marini, Francesco Cosentino, Francesca Di Donato, Angelo Antonio D'Archivio
Summary: This study aimed to develop a potentially non-destructive and routine-compatible method for the geographical traceability of high-valued Italian chickpeas. By analyzing the spectral information of the outer and inner parts of the kernels, it was found that the spectral analysis of the outer part yielded accurate and reliable results, indicating the possibility of non-destructive authentication.