A surface-imprinted surface-enhanced Raman scattering sensor for histamine detection based on dual semiconductors and Ag nanoparticles

A highly sensitive molecularly imprinted surface-enhanced Raman scattering (SERS) sensor was developed for selective detection of histamine. A combination of two semiconductors and Ag nanoparticles (NPs) was used as the SERS substrate. The SERS was induced by Ag NPs plasmon resonances as well as charge-transfer between the semiconductors and the Ag NPs. The Raman intensity and the logarithm of the histamine concentration were linear over the range 10(-8)-10(-3) mol L-1. The sensor exhibited good selectivity and had a sensitivity limit of 3.088 x 10(-9) mol L-1. Histamine was detected in a spiked liquor sample, and its recoveries were in the range of 89.89%-109.18%.

Automated summary

A highly sensitive molecularly imprinted surface-enhanced Raman scattering sensor has been developed for selective detection of histamine, showing good linearity and sensitivity. In spiked liquor samples, histamine was accurately detected with high recoveries.