High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice

A Senescence-Centric View of Aging: Implications for Longevity and Disease

(2020) M. Borghesan et al.   TRENDS IN CELL BIOLOGY

Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

(2019) Allyson K. Palmer et al.   AGING CELL

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

(2019) Mikolaj Ogrodnik et al.   Cell Metabolism

The impact of dietary protein intake on longevity and metabolic health

(2019) Munehiro Kitada et al.   EBioMedicine

From discoveries in ageing research to therapeutics for healthy ageing

(2019) Judith Campisi et al.   NATURE

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

The effects of graded caloric restriction: XII. Comparison of mouse to human impact on cellular senescence in the colon

(2018) Luigi Fontana et al.   AGING CELL

Dietary Fat, but Not Protein or Carbohydrate, Regulates Energy Intake and Causes Adiposity in Mice

(2018) Sumei Hu et al.   Cell Metabolism

Senolytics improve physical function and increase lifespan in old age

(2018) Ming Xu et al.   NATURE MEDICINE

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue

(2016) Marissa J. Schafer et al.   DIABETES

Calories or protein? The effect of dietary restriction on lifespan in rodents is explained by calories alone

(2016) J.R. Speakman et al.   EXPERIMENTAL GERONTOLOGY

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

(2016) Pierpaola Davalli et al.   Oxidative Medicine and Cellular Longevity

Adult-onset, short-term dietary restriction reduces cell senescence in mice

(2016) Chunfang Wang et al.   Aging-US

Promoting Health and Longevity through Diet: From Model Organisms to Humans

(2015) Luigi Fontana et al.   CELL

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

(2015) Nicolás Herranz et al.   NATURE CELL BIOLOGY

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

(2015) Remi-Martin Laberge et al.   NATURE CELL BIOLOGY

Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice

(2015) Samantha M. Solon-Biet et al.   Cell Reports

The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

(2014) Samantha M. Solon-Biet et al.   Cell Metabolism

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Role of interleukins in obesity: implications for metabolic disease

(2014) Mark A. Febbraio   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Not so hot: Optimal housing temperatures for mice to mimic the thermal environment of humans

(2012) John R. Speakman et al.   Molecular Metabolism

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

Growth stimulation leads to cellular senescence when the cell cycle is blocked

(2010) Zoya N. Demidenko et al.   CELL CYCLE

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Diet-induced obesity increases NF-κB signaling in reporter mice

(2009) Harald Carlsen et al.   Genes and Nutrition

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

(2009) Prospective Studies Collaboration   LANCET

Cell surface-bound IL-1  is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

(2009) A. V. Orjalo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity Increases Vascular Senescence and Susceptibility to Ischemic Injury Through Chronic Activation of Akt and mTOR

(2009) C.-Y. Wang et al.   Science Signaling

Effect of Dietary Protein Level and Origin on the Redox Status in the Digestive Tract of Mice

(2008) Chunmei Gu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES