Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat

A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

(2021) Hebaallah Mamdouh Hashiesh et al.   BIOMEDICINE & PHARMACOTHERAPY

β‐Caryophyllene may attenuate hyperoxaluria‐induced kidney dysfunction in rats by regulating stress marker KIM‐1/MCP‐1 and NF‐κB signaling pathway

(2021) Xia Xu et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

β-Caryophyllene attenuates lipopolysaccharide-induced acute lung injury via inhibition of the MAPK signalling pathway

(2021) Yong Zhang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Danshensu attenuates cisplatin-induced nephrotoxicity through activation of Nrf2 pathway and inhibition of NF-κB

(2021) Chen Yu et al.   BIOMEDICINE & PHARMACOTHERAPY

Vitamin D 3 and calcium cosupplementation alleviates cadmium hepatotoxicity in the rat: Enhanced antioxidative and anti‐inflammatory actions by remodeling cellular calcium pathways

(2020) Mohamed El‐Boshy et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Diverse Role of TGF-β in Kidney Disease

(2020) Yue-Yu Gu et al.   Frontiers in Cell and Developmental Biology

β-Caryophyllene inhibits high glucose-induced oxidative stress, inflammation and extracellular matrix accumulation in mesangial cells

(2020) Heng Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of the AMP-related kinase (AMPK) induces renal vasodilatation and downregulates Nox-derived reactive oxygen species (ROS) generation

(2020) Claudia Rodríguez et al.   Redox Biology

Therapeutic Potential of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications

(2020) Hebaallah Mamdouh Hashiesh et al.   Nutrients

Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation

(2020) Rosaria Scandiffio et al.   Nutrients

Canagliflozin ameliorates renal oxidative stress and inflammation by stimulating AMPK–Akt–eNOS pathway in the isoprenaline-induced oxidative stress model

(2020) Raquibul Hasan et al.   Scientific Reports

NFκB and Kidney Injury

(2019) Ning Song et al.   Frontiers in Immunology

Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat

(2019) Mohamed El-Boshy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Anti-arthritic effect of β-caryophyllene and its ameliorative role on methotrexate and/or leflunomide-induced side effects in arthritic rats

(2019) Sawsan M.A. El-Sheikh et al.   LIFE SCIENCES

Acute and Chronic Iron Overloading Differentially Modulates the Expression of Cellular Iron-homeostatic Molecules in Normal Rat Kidney

(2018) Bassem Refaat et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Non-clinical toxicity of β -caryophyllene, a dietary cannabinoid: Absence of adverse effects in female Swiss mice

(2018) George Laylson da Silva Oliveira et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

β-Caryophyllene, the major constituent of copaiba oil, reduces systemic inflammation and oxidative stress in arthritic rats

(2018) Ana P. Ames-Sibin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

β-Caryophyllene Pretreatment Alleviates Focal Cerebral Ischemia-Reperfusion Injury by Activating PI3K/Akt Signaling Pathway

(2017) Qian Zhang et al.   NEUROCHEMICAL RESEARCH

Sulfasalazine induces mitochondrial dysfunction and renal injury

(2017) Hossein Niknahad et al.   RENAL FAILURE

Toxicological Evaluation of β-Caryophyllene Oil

(2016) D. Schmitt et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes

(2016) Ryosuke Kamikubo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Renal Effects of Long-Term Treatment with 5-Aminosalicylic Acid

(2016) Harshna Patel et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

Clinical Features and HLA Association of 5-Aminosalicylate (5-ASA)-induced Nephrotoxicity in Inflammatory Bowel Disease

(2015) Graham A. Heap et al.   Journal of Crohns & Colitis

Sulfasalazine-induced renal injury in rats and the protective role of thiol-reductants

(2015) Reza Heidari et al.   RENAL FAILURE

NF-κB in inflammation and renal diseases

(2015) Haisong Zhang et al.   Cell and Bioscience

Earlier recognition of nephrotoxicity using novel biomarkers of acute kidney injury

(2011) W. Stephen Waring et al.   CLINICAL TOXICOLOGY

Kidney-targeting Smad7 gene transfer inhibits renal TGF-β/MAD homologue (SMAD) and nuclear factor κB (NF-κB) signalling pathways, and improves diabetic nephropathy in mice

(2011) S. M. Ka et al.   DIABETOLOGIA

Oxidative stress as a mechanism underlying sulfasalazine-induced toxicity

(2011) Victoria Linares et al.   Expert Opinion On Drug Safety

Reversal of refractory sulfasalazine-related renal failure after treatment with corticosteroids

(2010) Polichronis Alivanis et al.   CLINICAL THERAPEUTICS

Lipid peroxidation and antioxidant status in kidney and liver of rats treated with sulfasalazine

(2008) Victoria Linares et al.   TOXICOLOGY