Improvement of the pharmacokinetics and antifibrotic effects of nintedanib by intrapulmonary administration of a nintedanib–hydroxypropyl-γ-cyclodextrin inclusion complex in mice with bleomycin-induced pulmonary fibrosis

Advantages of the combined use of cyclodextrins and nanocarriers in drug delivery: A review

(2020) Paola Mura   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycin-induced pulmonary fibrosis

(2020) Kohei Togami et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Strategies to Enhance Drug Absorption via Nasal and Pulmonary Routes

(2019) Maliheh Ghadiri et al.   Pharmaceutics

Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets

(2019) Beatriz Ballester et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent advances in aerosolised drug delivery

(2019) Akshay Chandel et al.   BIOMEDICINE & PHARMACOTHERAPY

Treatment of acute lung injury and early- and late-stage pulmonary fibrosis with combination emulsion siRNA polyplexes

(2019) Yixin Wang et al.   JOURNAL OF CONTROLLED RELEASE

Carriers for the Targeted Delivery of Aerosolized Macromolecules for Pulmonary Pathologies

(2018) Nashwa Osman et al.   Expert Opinion on Drug Delivery

Nintedanib-cyclodextrin complex to improve bio-activity and intestinal permeability

(2018) Bhuvaneshwar Vaidya et al.   CARBOHYDRATE POLYMERS

Evaluation of permeability alteration and epithelial–mesenchymal transition induced by transforming growth factor-β 1 in A549, NCI-H441, and Calu-3 cells: Development of an in vitro model of respiratory epithelial cells in idiopathic pulmonary fibrosis

(2017) Kohei Togami et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Atomized paclitaxel liposome inhalation treatment of bleomycin-induced pulmonary fibrosis in rats

(2016) Y. Zhou et al.   GENETICS AND MOLECULAR RESEARCH

Tumor distribution and anti-tumor effect of doxorubicin following intrapulmonary administration to mice with metastatic lung tumor

(2016) Yukimune Kanehira et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Evaluation of the potential toxicity of unmodified and modified cyclodextrins on murine blood-brain barrier endothelial cells

(2016) Sergey Shityakov et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Nintedanib in the treatment of idiopathic pulmonary fibrosis

(2015) Mariano E. Mazzei et al.   Therapeutic Advances in Respiratory Disease

Targeting Inhaled Therapy beyond the Lungs

(2014) Ninell P. Mortensen et al.   RESPIRATION

Lung transplantation in idiopathic pulmonary fibrosis: a systematic review of the literature

(2014) Kristin D Kistler et al.   BMC Pulmonary Medicine

Possible Involvement of Pirfenidone Metabolites in the Antifibrotic Action of a Therapy for Idiopathic Pulmonary Fibrosis

(2013) Kohei Togami et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Effects of β-cyclodextrin on the intestinal absorption of berberine hydrochloride, a P-glycoprotein substrate

(2013) Ye Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Pulmonary Administration of a Water-Soluble Curcumin Complex Reduces Severity of Acute Lung Injury

(2012) Madathilparambil V. Suresh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Aerosol-Based Efficient Delivery of Clarithromycin, a Macrolide Antimicrobial Agent, to Lung Epithelial Lining Fluid and Alveolar Macrophages for Treatment of Respiratory Infections

(2012) Kohei Togami et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Local delivery of biodegradable pirfenidone nanoparticles ameliorates bleomycin-induced pulmonary fibrosis in mice

(2012) Ruchit Trivedi et al.   NANOTECHNOLOGY

Interpretation and prediction of inhaled drug particle accumulation in the lung and its associated toxicity

(2011) Rhys M. Jones et al.   XENOBIOTICA

Clinical Course and Prediction of Survival in Idiopathic Pulmonary Fibrosis

(2010) Brett Ley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

In vitro characterization and pharmacokinetics in mice following pulmonary delivery of itraconazole as cyclodextrin solubilized solution

(2010) Wei Yang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Pharmaceutical applications of cyclodextrins: basic science and product development

(2010) Thorsteinn Loftsson et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

BIBF 1120: Triple Angiokinase Inhibitor with Sustained Receptor Blockade and Good Antitumor Efficacy

(2008) F. Hilberg et al.   CANCER RESEARCH

Formulation of rifampicin–cyclodextrin complexes for lung nebulization

(2008) Frédéric Tewes et al.   JOURNAL OF CONTROLLED RELEASE