Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors

Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19

(2021) Kas Steuten et al.   ACS Infectious Diseases

SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies

(2021) Markus Hoffmann et al.   CELL

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti COVID-19 Drugs: Need for More Clinical Evidence and Global Action

(2020) Zakir Khan et al.   ADVANCES IN THERAPY

Could Chloroquine /Hydroxychloroquine Be Harmful in Coronavirus Disease 2019 (COVID-19) Treatment?

(2020) Maurizio Guastalegname et al.   CLINICAL INFECTIOUS DISEASES

Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach

(2020) Sukanth Kumar Enmozhi et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial

(2020) Yeming Wang et al.   LANCET

A regioselective synthesis of 7-methyl juglone and its derivatives

(2020) Jiahua Cui et al.   NATURAL PRODUCT RESEARCH

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

Remdesivir for the Treatment of Covid-19 — Preliminary Report

(2020) John H. Beigel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

(2020) Wenhao Dai et al.   SCIENCE

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

(2020) Linlin Zhang et al.   SCIENCE

and Animal Models for SARS-CoV-2 research

(2020) Kazuo Takayama   TRENDS IN PHARMACOLOGICAL SCIENCES

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

(2020) Brandi N. Williamson et al.   NATURE

Covid-19: Hydroxychloroquine does not benefit hospitalised patients, UK trial finds

(2020) Ingrid Torjesen   BMJ-British Medical Journal

Natural COX-2 inhibitors as promising anti-inflammatory agents: an update

(2020) Jiahua Cui et al.   CURRENT MEDICINAL CHEMISTRY

Efficacy of chloroquine or hydroxychloroquine in COVID-19 patients: a systematic review and meta-analysis

(2020) Zakariya Kashour et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Animal models for COVID-19

(2020) César Muñoz-Fontela et al.   NATURE

Potential bioactive glycosylated flavonoids as SARS-CoV-2 main protease inhibitors: A molecular docking and simulation studies

(2020) Sabri Ahmed Cherrak et al.   PLoS One

Anti-SARS-CoV Natural Products With the Potential to Inhibit SARS-CoV-2 (COVID-19)

(2020) Surjeet Verma et al.   Frontiers in Pharmacology

In silico analysis of selected alkaloids against main protease (Mpro) of SARS-CoV-2

(2020) Saksham Garg et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The SARS-CoV-2 RNA–protein interactome in infected human cells

(2020) Nora Schmidt et al.   Nature Microbiology

Structure-based discovery of antiviral inhibitors targeting the E dimer interface of Japanese encephalitis virus

(2019) Chuantao Ye et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synthesis of 4,8-dimethoxy-1-naphthol via an acetyl migration

(2016) Qijing Zhang et al.   SYNTHETIC COMMUNICATIONS

Design and Synthesis of New α-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression

(2015) Jiahua Cui et al.   JOURNAL OF MEDICINAL CHEMISTRY

An efficient multigram synthesis of juglone methyl ether

(2015) Jia-hua Cui et al.   JOURNAL OF CHEMICAL RESEARCH

An Efficient Synthesis of 5,6-Dimethoxy 1- and 2-NaphtholsviaTeuber Reaction

(2013) Jia-hua Cui et al.   JOURNAL OF THE CHINESE CHEMICAL SOCIETY

Profiling of Substrate Specificities of 3C-Like Proteases from Group 1, 2a, 2b, and 3 Coronaviruses

(2011) Chi-Pang Chuck et al.   PLoS One

Cytotoxic activity of naphthoquinones with special emphasis on juglone and its 5-O-methyl derivative

(2010) Raquel Carvalho Montenegro et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells

(2009) B. Kiran Aithal et al.   CELL BIOLOGY INTERNATIONAL