Design, synthesis and biological activity evaluation of novel scopoletin-NO donor derivatives against MCF-7 human breast cancer in vitro and in vivo

Novel NO-releasing scopoletin derivatives induce cell death via mitochondrial apoptosis pathway and cell cycle arrest

(2020) Zhixian Shi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Nitric oxide in cellular adaptation and disease

(2020) Benjamin N. Gantner et al.   Redox Biology

Design and synthesis of functionalized coumarins as potential anti-austerity agents that eliminates cancer cells' tolerance to nutrition starvation

(2019) Suresh Awale et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and biological evaluation of coumarin-3-carboxamides as selective carbonic anhydrase IX and XII inhibitors

(2019) Pavitra S. Thacker et al.   BIOORGANIC CHEMISTRY

Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery

(2018) Nicholas Thomford et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis and Spectroscopic Characterization of Some Hydrazone and 2H -benzopyranone Derivatives as Antitumor Agents

(2018) Hana M. A. Abumelha   JOURNAL OF HETEROCYCLIC CHEMISTRY

Nitric oxide signalling in cardiovascular health and disease

(2018) Charlotte Farah et al.   Nature Reviews Cardiology

Discovery of novel NO-releasing celastrol derivatives with Hsp90 inhibition and cytotoxic activities

(2018) Na Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

SOURCES OF VASCULAR NITRIC OXIDE AND REACTIVE OXYGEN SPECIES AND THEIR REGULATION

(2018) Jesús Tejero et al.   PHYSIOLOGICAL REVIEWS

Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells

(2017) Satoshi Endo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Potent Inhibition of Nitric Oxide-Releasing Bifendate Derivatives against Drug-Resistant K562/A02 Cells in Vitro and in Vivo

(2017) Xiaoke Gu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nitric Oxide Donor-Based Cancer Therapy: Advances and Prospects

(2017) Zhangjian Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Pharmacogenomics of Scopoletin in Tumor Cells

(2016) Ean-Jeong Seo et al.   MOLECULES

Synthesis, in vitro and in vivo antitumor activity of scopoletin-cinnamic acid hybrids

(2015) Linhu Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Antitumor Evaluation of Novel Histone Deacetylase Inhibitors Equipped with a Phenylsulfonylfuroxan Module as a Nitric Oxide Donor

(2015) Wenwen Duan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of CDDO–Amino Acid–Nitric Oxide Donor Trihybrids as Potential Antitumor Agents against Both Drug-Sensitive and Drug-Resistant Colon Cancer

(2015) Yong Ai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural Products as a Vital Source for the Discovery of Cancer Chemotherapeutic and Chemopreventive Agents

(2015) Gordon M. Cragg et al.   MEDICAL PRINCIPLES AND PRACTICE

Hybrids of Phenylsulfonylfuroxan and Coumarin as Potent Antitumor Agents

(2014) Ming-Ming Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel Hybrids of (Phenylsulfonyl)furoxan and Anilinopyrimidine as Potent and Selective Epidermal Growth Factor Receptor Inhibitors for Intervention of Non-Small-Cell Lung Cancer

(2013) Chun Han et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of scopoletin derivatives

(2012) Xueting Cai et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and in vitro antitumor activity of novel scopoletin derivatives

(2012) Wukun Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Review Scopoletin – A Coumarin Phytoalexin with Medicinal Properties

(2012) G. J. Benoit Gnonlonfin et al.   CRITICAL REVIEWS IN PLANT SCIENCES

Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin

(2011) Thomas Efferth et al.   PHYTOMEDICINE