Hepatic CPT1A Facilitates Liver–Adipose Cross Talk via Induction of FGF21 in Mice

Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis

(2020) Qing Ye et al.   Lancet Gastroenterology & Hepatology

Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output

(2019) Junling Liu et al.   EBioMedicine

Fibroblast Growth Factor 21 and Browning of White Adipose Tissue

(2019) Daniel Cuevas-Ramos et al.   Frontiers in Physiology

FGF21 Alleviates Hepatic Endoplasmic Reticulum Stress under Physiological Conditions

(2018) Ryuto MARUYAMA et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators

(2018) Elena Piccinin et al.   Nature Reviews Gastroenterology & Hepatology

Fibroblast growth factor 21 protects rat cardiomyocytes from endoplasmic reticulum stress by promoting the fibroblast growth factor receptor 1-extracellular signal-regulated kinase 1/2 signaling pathway

(2017) Pingping Liang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

(2017) Alison Iroz et al.   Cell Reports

Understanding the Physiology of FGF21

(2016) Ffolliott Martin Fisher et al.   Annual Review of Physiology

The FGF21–adiponectin axis in controlling energy and vascular homeostasis

(2016) Xiaoyan Hui et al.   Journal of Molecular Cell Biology

Hepatic Fatty Acid Oxidation Restrains Systemic Catabolism during Starvation

(2016) Jieun Lee et al.   Cell Reports

Adiponectin Enhances Cold-Induced Browning of Subcutaneous Adipose Tissue via Promoting M2 Macrophage Proliferation

(2015) Xiaoyan Hui et al.   Cell Metabolism

NAFLD: A multisystem disease

(2015) Christopher D. Byrne et al.   JOURNAL OF HEPATOLOGY

Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism

(2015) Shawna E. Wicks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fructose ingestion acutely stimulates circulating FGF21 levels in humans

(2015) Jody R. Dushay et al.   Molecular Metabolism

ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress

(2014) Xiao-shan Wan et al.   Biomed Research International

The global NAFLD epidemic

(2013) Rohit Loomba et al.   Nature Reviews Gastroenterology & Hepatology

Carnitine Palmitoyltransferase-1b Deficiency Aggravates Pressure Overload–Induced Cardiac Hypertrophy Caused by Lipotoxicity

(2012) Lan He et al.   CIRCULATION

Loss of Perivascular Adipose Tissue on Peroxisome Proliferator–Activated Receptor-γ Deletion in Smooth Muscle Cells Impairs Intravascular Thermoregulation and Enhances Atherosclerosis

(2012) Lin Chang et al.   CIRCULATION

Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice

(2012) W. Keung et al.   DIABETES

Sodium Butyrate Stimulates Expression of Fibroblast Growth Factor 21 in Liver by Inhibition of Histone Deacetylase 3

(2012) H. Li et al.   DIABETES

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis

(2011) R. Conti et al.   DIABETES

Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes

(2009) Katsumi Iizuka et al.   FEBS LETTERS

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY

Inhibition of mitochondrial fatty acid oxidation in vivo only slightly suppresses gluconeogenesis but enhances clearance of glucose in mice

(2008) Terry G. J. Derks et al.   HEPATOLOGY