Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy

Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma

(2020) Aparna Bhaduri et al.   Cell Stem Cell

The Glioma Stem Cell Model in the Era of Single-Cell Genomics

(2020) Mario L. Suvà et al.   CANCER CELL

Roadmap for the Emerging Field of Cancer Neuroscience

(2020) Michelle Monje et al.   CELL

Cell Lineage-Based Stratification for Glioblastoma

(2020) Zilai Wang et al.   CANCER CELL

Beyond thrombosis: the impact of tissue factor signaling in cancer

(2020) Dusten Unruh et al.   Journal of Hematology & Oncology

Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy

(2020) Charles P. Couturier et al.   Nature Communications

High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging

(2020) Xuanhua P. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Stem Cells: The Architects of the Tumor Ecosystem

(2019) Briana C. Prager et al.   Cell Stem Cell

Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction

(2019) Sheila Alcantara Llaguno et al.   NATURE NEUROSCIENCE

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

(2019) Nishani Rajakulendran et al.   GENES & DEVELOPMENT

Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis

(2019) Qinjie Weng et al.   Cell Stem Cell

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

(2019) Graham MacLeod et al.   Cell Reports

Primary cilium and brain aging: role in neural stem cells, neurodegenerative diseases and glioblastoma

(2019) María Álvarez-Satta et al.   AGEING RESEARCH REVIEWS

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

(2019) Cyril Neftel et al.   CELL

Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer

(2019) Ryan C. Gimple et al.   GENES & DEVELOPMENT

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

(2018) Elham Azizi et al.   CELL

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

(2018) James J Morrow et al.   NATURE MEDICINE

Human glioblastoma arises from subventricular zone cells with low-level driver mutations

(2018) Joo Ho Lee et al.   NATURE

A stromal cell population that inhibits adipogenesis in mammalian fat depots

(2018) Petra C. Schwalie et al.   NATURE

Single-cell transcriptome analysis of lineage diversity in high-grade glioma

(2018) Jinzhou Yuan et al.   Genome Medicine

Brain Tumor Stem Cells Remain in Play

(2017) Luis F. Parada et al.   JOURNAL OF CLINICAL ONCOLOGY

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

(2017) Xiaoyang Lan et al.   NATURE

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma

(2017) Spyros Darmanis et al.   Cell Reports

Isolation, culture and analysis of adult subependymal neural stem cells

(2016) Germán Belenguer et al.   DIFFERENTIATION

GlioVis data portal for visualization and analysis of brain tumor expression datasets

(2016) Robert L. Bowman et al.   NEURO-ONCOLOGY

InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

(2015) Henry Heberle et al.   BMC BIOINFORMATICS

Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes

(2015) Sheila R. Alcantara Llaguno et al.   CANCER CELL

Molecular Identity of Human Outer Radial Glia during Cortical Development

(2015) Alex A. Pollen et al.   CELL

Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells

(2015) Chad M. Toledo et al.   Cell Reports

Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma

(2014) Robert J. Vanner et al.   CANCER CELL

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

(2014) Mario L. Suvà et al.   CELL

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity

(2013) Peng Li et al.   NATURE NEUROSCIENCE

Molecular regulation of stem cell quiescence

(2013) Tom H. Cheung et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

(2012) Jian Chen et al.   CELL

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

(2009) Sheila Alcantara Llaguno et al.   CANCER CELL

Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution

(2009) S G M Piccirillo et al.   ONCOGENE

Stem cell concepts renew cancer research

(2008) J. E. Dick   BLOOD

Traumatic Brain Injury-Induced Hippocampal Neurogenesis Requires Activation of Early Nestin-Expressing Progenitors

(2008) T.-S. Yu et al.   JOURNAL OF NEUROSCIENCE