Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials

mRNA in cancer immunotherapy: beyond a source of antigen

(2021) Lien Van Hoecke et al.   Molecular Cancer

Simple Peptide Quantification Approach for MS-Based Proteomics Quality Control

(2020) Teresa Mendes Maia et al.   ACS Omega

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

(2020) Daniel K. Wells et al.   CELL

mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer

(2020) Gal Cafri et al.   JOURNAL OF CLINICAL INVESTIGATION

Application of mass spectrometry-based MHC immunopeptidome profiling in neoantigen identification for tumor immunotherapy

(2019) Xiaomei Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

An accelerated, clinical-grade protocol to generate high yields of type 1-polarizing messenger RNA–loaded dendritic cells for cancer vaccination

(2018) E. BRABANTS et al.   CYTOTHERAPY

Cancer Neoantigens

(2018) Ton N. Schumacher et al.   Annual Review of Immunology

Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification

(2018) Brendan Bulik-Sullivan et al.   NATURE BIOTECHNOLOGY

Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems

(2017) S Guan et al.   GENE THERAPY

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

(2017) Ugur Sahin et al.   NATURE

Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

(2016) Alena Gros et al.   NATURE MEDICINE

Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

(2016) Michal Bassani-Sternberg et al.   Nature Communications

An overview of bioinformatics tools for epitope prediction: Implications on vaccine development

(2015) Ruth E. Soria-Guerra et al.   JOURNAL OF BIOMEDICAL INFORMATICS

mRNA-based dendritic cell vaccines

(2014) Daphné Benteyn et al.   Expert Review of Vaccines

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

mRNA

(2013) Sandra Van Lint et al.   Human Vaccines & Immunotherapeutics

Exploiting the Mutanome for Tumor Vaccination

(2012) J. C. Castle et al.   CANCER RESEARCH

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY