Mechanistic similarities in recognition of histone tails and DNA by epigenetic readers

The molecular basis of selective DNA binding by the BRG1 AT-hook and bromodomain

(2020) Julio C. Sanchez et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MORC3 Is a Target of the Influenza A Viral Protein NS1

(2019) Yi Zhang et al.   STRUCTURE

Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin

(2019) Brianna J. Klein et al.   STRUCTURE

Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation

(2019) Brianna J. Klein et al.   Nature Communications

Structure of H3K36-methylated nucleosome–PWWP complex reveals multivalent cross-gyre binding

(2019) Haibo Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Reading More than Histones: The Prevalence of Nucleic Acid Binding among Reader Domains

(2018) Tyler Weaver et al.   MOLECULES

Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain

(2018) Brianna J. Klein et al.   Nature Communications

Transcription control by the ENL YEATS domain in acute leukaemia

(2017) Michael A. Erb et al.   NATURE

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia

(2017) Liling Wan et al.   NATURE

Recognition of Histone H3K14 Acylation by MORF

(2017) Brianna J. Klein et al.   STRUCTURE

DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes

(2017) Emma A. Morrison et al.   Nature Communications

Accessibility of the histone H3 tail in the nucleosome for binding of paired readers

(2017) Jovylyn Gatchalian et al.   Nature Communications

YEATS2 is a selective histone crotonylation reader

(2016) Dan Zhao et al.   CELL RESEARCH

Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain

(2016) Yuanyuan Li et al.   MOLECULAR CELL

Insights into newly discovered marks and readers of epigenetic information

(2016) Forest H Andrews et al.   Nature Chemical Biology

The Taf14 YEATS domain is a reader of histone crotonylation

(2016) Forest H Andrews et al.   Nature Chemical Biology

Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin

(2016) Sisi Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A bromodomain–DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT

(2016) Thomas C. R. Miller et al.   Nature Communications

Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase

(2016) Forest H. Andrews et al.   Cell Reports

Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response

(2015) Erin K. Shanle et al.   GENES & DEVELOPMENT

Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation

(2015) Brianna J. Klein et al.   NUCLEIC ACIDS RESEARCH

Hitting the ‘mark’: Interpreting lysine methylation in the context of active transcription

(2014) Glenn G. Wozniak et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation

(2014) Yuanyuan Li et al.   CELL

Readout of Epigenetic Modifications

(2013) Dinshaw J. Patel et al.   Annual Review of Biochemistry

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

(2013) M.-E. Lalonde et al.   GENES & DEVELOPMENT

Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes

(2013) Jocelyn O. Eidahl et al.   NUCLEIC ACIDS RESEARCH

The double PHD finger domain of MOZ/MYST3 induces  -helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification

(2013) I. Dreveny et al.   NUCLEIC ACIDS RESEARCH

Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain

(2013) Rick van Nuland et al.   Epigenetics & Chromatin

Binding of PHF1 Tudor to H3K36me3 enhances nucleosome accessibility

(2013) Catherine A. Musselman et al.   Nature Communications

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

(2012) Panagis Filippakopoulos et al.   CELL

Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription

(2012) Y. Qiu et al.   GENES & DEVELOPMENT

Tandem PHD Fingers of MORF/MOZ Acetyltransferases Display Selectivity for Acetylated Histone H3 and Are Required for the Association with Chromatin

(2012) Muzaffar Ali et al.   JOURNAL OF MOLECULAR BIOLOGY

Solution structure of an atypical PHD finger in BRPF2 and its interaction with DNA

(2012) Lei Liu et al.   JOURNAL OF STRUCTURAL BIOLOGY

Quantitative Chemical Proteomics Approach To Identify Post-translational Modification-Mediated Protein–Protein Interactions

(2012) Xiang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intrinsic Nucleic Acid-Binding Activity of Chp1 Chromodomain Is Required for Heterochromatic Gene Silencing

(2012) Mayumi Ishida et al.   MOLECULAR CELL

Perceiving the epigenetic landscape through histone readers

(2012) Catherine A Musselman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA

(2011) Yu Qiu et al.   BIOCHEMICAL JOURNAL

Recognition of Unmodified Histone H3 by the First PHD Finger of Bromodomain-PHD Finger Protein 2 Provides Insights into the Regulation of Histone Acetyltransferases Monocytic Leukemic Zinc-finger Protein (MOZ) and MOZ-related factor (MORF)

(2011) Su Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b

(2010) Lei Zeng et al.   NATURE

Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain

(2010) Daesung Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY