RNA gradients: Shapers of 3D genome architecture

A nuclear enterprise: zooming in on nuclear organization and gene expression control in the African trypanosome

(2021) Joana R. C. Faria   PARASITOLOGY

Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes

(2021) Joana Faria et al.   Nature Microbiology

Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome

(2021) J. Yuyang Lu et al.   CELL RESEARCH

Transcription organizes euchromatin via microphase separation

(2021) Lennart Hilbert et al.   Nature Communications

Non-coding RNAs in chromatin folding and nuclear organization

(2021) Sergey V. Razin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction

(2021) Kevin Michael Creamer et al.   MOLECULAR CELL

Nuclear compartmentalization as a mechanism of quantitative control of gene expression

(2021) Prashant Bhat et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA promotes the formation of spatial compartments in the nucleus

(2021) Sofia A. Quinodoz et al.   CELL

Three-dimensional genome organization via triplex-forming RNAs

(2021) Irene Farabella et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Viewing Nuclear Architecture through the Eyes of Nocturnal Mammals

(2020) Yana Feodorova et al.   TRENDS IN CELL BIOLOGY

Radial Organization in the Mammalian Nucleus

(2020) Nicola Crosetto et al.   Frontiers in Genetics

Repetitive RNAs as Regulators of Chromatin-Associated Subcompartment Formation by Phase Separation

(2020) Lukas Frank et al.   JOURNAL OF MOLECULAR BIOLOGY

GPSeq reveals the radial organization of chromatin in the cell nucleus

(2020) Gabriele Girelli et al.   NATURE BIOTECHNOLOGY

Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation

(2020) J. Yuyang Lu et al.   Cell Reports

Nuclear hubs built on RNAs and clustered organization of the genome

(2020) Kelly P. Smith et al.   CURRENT OPINION IN CELL BIOLOGY

RNA contributions to the form and function of biomolecular condensates

(2020) Christine Roden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The nucleolus as a multiphase liquid condensate

(2020) Denis L. J. Lafontaine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gene regulation by long non-coding RNAs and its biological functions

(2020) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA: Nuclear Glue for Folding the Genome

(2019) Ryu-Suke Nozawa et al.   TRENDS IN CELL BIOLOGY

Principles of genome folding into topologically associating domains

(2019) Quentin Szabo et al.   Science Advances

Role of nuclear RNA in regulating chromatin structure and transcription

(2019) Davide Michieletto et al.   CURRENT OPINION IN CELL BIOLOGY

Heterochromatin drives compartmentalization of inverted and conventional nuclei

(2019) Martin Falk et al.   NATURE

Chromatin-associated RNAs as facilitators of functional genomic interactions

(2019) Xiao Li et al.   NATURE REVIEWS GENETICS

Differential contribution of steady‐state RNA and active transcription in chromatin organization

(2019) A Rasim Barutcu et al.   EMBO REPORTS

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy

(2018) J.G.C. Peeters et al.   Autophagy

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler

(2018) Yu Chen et al.   JOURNAL OF CELL BIOLOGY

Genome organization and DNA accessibility control antigenic variation in trypanosomes

(2018) Laura S. M. Müller et al.   NATURE

The X chromosome in space

(2017) Teddy Jégu et al.   NATURE REVIEWS GENETICS

Ten principles of heterochromatin formation and function

(2017) Robin C. Allshire et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Organization and function of the 3D genome

(2016) Boyan Bonev et al.   NATURE REVIEWS GENETICS

Stable C0T-1 Repeat RNA Is Abundant and Is Associated with Euchromatic Interphase Chromosomes

(2014) Lisa L. Hall et al.   CELL

Antigenic variation in African trypanosomes

(2014) David Horn   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Long noncoding RNAs: an emerging link between gene regulation and nuclear organization

(2014) Sofia Quinodoz et al.   TRENDS IN CELL BIOLOGY

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Triplexator: Detecting nucleic acid triple helices in genomic and transcriptomic data

(2012) F. A. Buske et al.   GENOME RESEARCH

Regulation of X-chromosome inactivation by the X-inactivation centre

(2011) Sandrine Augui et al.   NATURE REVIEWS GENETICS

Nuclear Speckles

(2010) D. L. Spector et al.   Cold Spring Harbor Perspectives in Biology

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE