Non-centrosomal microtubules at kinetochores promote rapid chromosome biorientation during mitosis in human cells

Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces

(2021) Mihaela Jagrić et al.   eLife

Mitotic spindle: lessons from theoretical modeling

(2021) Iva M. Tolić et al.   MOLECULAR BIOLOGY OF THE CELL

Role of spatial patterns and kinetochore architecture in spindle morphogenesis

(2021) Fioranna Renda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

(2020) Christopher Edelmaier et al.   eLife

Centrosome–nuclear axis repositioning drives the assembly of a bipolar spindle scaffold to ensure mitotic fidelity

(2020) Vanessa Nunes et al.   MOLECULAR BIOLOGY OF THE CELL

Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth

(2019) Ana F. David et al.   JOURNAL OF CELL BIOLOGY

Force Generated by Two Kinesin Motors Depends on the Load Direction and Intermolecular Coupling

(2019) Hamid Khataee et al.   PHYSICAL REVIEW LETTERS

High-resolution imaging reveals how the spindle midzone impacts chromosome movement

(2019) Melissa C. Pamula et al.   JOURNAL OF CELL BIOLOGY

Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity

(2019) Manas Chakraborty et al.   Nature Communications

Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis

(2019) Alexander JR Booth et al.   eLife

Electron tomography reveals aspects of spindle structure important for mechanical stability at metaphase

(2019) Eileen O'Toole et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubules assemble near most kinetochores during early prometaphase in human cells

(2018) Vitali Sikirzhytski et al.   JOURNAL OF CELL BIOLOGY

Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis

(2018) Carlos Sacristan et al.   NATURE CELL BIOLOGY

Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

(2018) Jose-Antonio Rodriguez-Rodriguez et al.   CURRENT BIOLOGY

Self-Assembly of the RZZ Complex into Filaments Drives Kinetochore Expansion in the Absence of Microtubule Attachment

(2018) Cláudia Pereira et al.   CURRENT BIOLOGY

Spindle assembly checkpoint satisfaction occurs via end-on but not lateral attachments under tension

(2017) Jonathan Kuhn et al.   JOURNAL OF CELL BIOLOGY

Mitotic spindle assembly in animal cells: a fine balancing act

(2017) Suzanna L. Prosser et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin protects mammalian eggs against chromosome segregation errors

(2017) Binyam Mogessie et al.   SCIENCE

Mechanisms of Mitotic Spindle Assembly

(2016) Sabine Petry   Annual Review of Biochemistry

Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores

(2016) Janko Kajtez et al.   Nature Communications

Thirty years of search and capture: The complex simplicity of mitotic spindle assembly

(2015) Rebecca Heald et al.   JOURNAL OF CELL BIOLOGY

Adaptive changes in the kinetochore architecture facilitate proper spindle assembly

(2015) Valentin Magidson et al.   NATURE CELL BIOLOGY

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1

(2015) Erik Voets et al.   Scientific Reports

Direct kinetochore–spindle pole connections are not required for chromosome segregation

(2014) Vitali Sikirzhytski et al.   JOURNAL OF CELL BIOLOGY

Force on spindle microtubule minus ends moves chromosomes

(2014) Mary Williard Elting et al.   JOURNAL OF CELL BIOLOGY

Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces

(2014) Marin Barisic et al.   NATURE CELL BIOLOGY

Fluorogenic probes for live-cell imaging of the cytoskeleton

(2014) Gražvydas Lukinavičius et al.   NATURE METHODS

Marking and Measuring Single Microtubules by PRC1 and Kinesin-4

(2013) Radhika Subramanian et al.   CELL

Crosstalk Between Microtubule Attachment Complexes Ensures Accurate Chromosome Segregation

(2013) D. K. Cheerambathur et al.   SCIENCE

Pivoting of microtubules around the spindle pole accelerates kinetochore capture

(2012) Iana Kalinina et al.   NATURE CELL BIOLOGY

Biophysics of mitosis

(2012) J. Richard McIntosh et al.   QUARTERLY REVIEWS OF BIOPHYSICS

The Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly

(2011) Valentin Magidson et al.   CELL

Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein

(2010) Radhika Subramanian et al.   CELL

Mechanisms of chromosome behaviour during mitosis

(2010) Claire E. Walczak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Antitumor activity of an allosteric inhibitor of centromere-associated protein-E

(2010) K. W. Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensing centromere tension: Aurora B and the regulation of kinetochore function

(2010) Michael A. Lampson et al.   TRENDS IN CELL BIOLOGY

Computer simulations predict that chromosome movements and rotations accelerate mitotic spindle assembly without compromising accuracy

(2009) R. Paul et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intramolecular Strain Coordinates Kinesin Stepping Behavior along Microtubules

(2008) Ahmet Yildiz et al.   CELL