Article
Engineering, Biomedical
Jose A. Contreras-Rozo, Monica M. Mata-Miranda, Gustavo J. Vazquez-Zapien, Raul J. Delgado-Macuil
Summary: Diabetes is a chronic metabolic disorder characterized by an increase in glucose caused by autoimmune destruction of insulin-producing cells or tissue resistance to insulin. It can lead to cardiovascular and renal complications, as well as retinopathy, causing a significant decline in the patient's health. Fourier transform infrared spectroscopy has emerged as a non-invasive method to accurately detect diabetes, and chemometric methods can improve its accuracy. However, there is currently no unified assay for its detection, and more research is needed to establish a single protocol for clinical settings.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2023)
Article
Physics, Applied
Bingbing Wang, Yulu Chen, Wulin Tong, Yangzhou Zhou, Jiajia Tao, Zewen Wang, Zuoru Dong, Hong Zhou, Zhanglong Fu, DiXiang Shao, Xiaodong Wang, Juncheng Cao
Summary: This study presents a novel blocked-impurity-band hybrid structure for terahertz radiation detection. The modulation effect of sub-wavelength metal grating on light absorption is analyzed, and the optical absorption and spectral response of the hybrid structure detectors are simulated. The results show selective absorption amplification and filtering effects, as well as significant absorption enhancement at specific wavelengths.
APPLIED PHYSICS LETTERS
(2022)
Article
Spectroscopy
A. Falamas, C. I. Faur, S. Ciupe, M. Chirila, H. Rotaru, M. Hedesiu, S. Cinta Pinzaru
Summary: This study tested a saliva samples preparation method for oral and oropharyngeal cancer diagnosis using micro-Raman and FT-IR spectroscopic techniques. Biomarker bands for cancer classification were identified, with a significant vibrational band at 2064 cm(-1) observed in both datasets. The oral and oropharyngeal cancer could be differentiated with 90% accuracy using micro-Raman data and 82% accuracy using FT-IR data.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Engineering, Biomedical
Miguel Sanchez-Brito, Francisco J. Luna-Rosas, Ricardo Mendoza-Gonzalez, Gustavo J. Vazquez-Zapien, Julio C. Martinez-Romo, Monica M. Mata-Miranda
Summary: Diabetes, a non-lethal disease, can lead to various complications if not diagnosed promptly, highlighting the importance of early detection for improving quality of life.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2021)
Article
Spectroscopy
Dongdong Ni, Heather E. Smyth, Michael J. Gidley, Daniel Cozzolino
Summary: This study aimed to compare the spectral characteristics of dry and whole saliva samples and to investigate the influence of gender and age on MIR spectra. The results showed that dried saliva spectra were more consistent and better at distinguishing individual differences. Specific MIR regions associated with age and gender were identified, particularly in relation to proteins and DNA.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Geochemistry & Geophysics
Busheng Xie, Wenfei Mao, Boqi Peng, Shengyu Zhou, Lixin Wu
Summary: Rock spectral analysis is a crucial field in hyperspectral remote sensing information processing. The study demonstrates that thermal infrared spectroscopy can accurately identify different rock types, and feature-oriented principal component analysis provides a fast method to establish a rock type identification model.
Article
Plant Sciences
Yuan Jin, Hongwu Tian, Zhen Gao, Guiyan Yang, Daming Dong
Summary: Rapid, non-destructive, and reliable detection of the oil content of corn seeds is achieved using a hand-held Raman spectrometer and a spectral peak decomposition algorithm. This method allows for the determination of oil content differences among seeds of varying maturity and different varieties.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Chemistry, Analytical
Weiyi Pang, Yu Xing, Camilo L. M. Morais, Qiufeng Lao, Shengle Li, Zipeng Qiao, You Li, Maneesh N. Singh, Valerio G. Barauna, Francis L. Martin, Zhiyong Zhang
Summary: Diabetes mellitus (DM) is a metabolic disease that is of increasing global concern. The diagnosis and detection of DM and pre-diabetes are currently complicated, expensive, and time-consuming. In this study, a discriminant model was developed using attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy combined with principal component analysis linear discriminant analysis (PCA-LDA), which resulted in a high accuracy rate of 97% for diagnosing DM and pre-diabetes. This approach has significant clinical implications for intervention and risk reduction.
Article
Biochemical Research Methods
Hidehiko Honda, Masato Yamamoto, Satoru Arata, Hirokazu Kobayashi, Masahiro Inagaki
Summary: This study identified two wavenumber regions by recording the infrared absorption spectra of gases surrounding Staphylococcus aureus, using a decision tree-based machine learning algorithm for classification. The results demonstrate the potential effectiveness of using absorbance measurement within these wavenumber regions to detect Staphylococcus aureus.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Green & Sustainable Science & Technology
Yuxi Cao, Peixian Li, Dengcheng Hao, Yong Lian, Yuanjian Wang, Sihai Zhao
Summary: The study established the relationship between normalized difference vegetation index (NDVI) and coherence coefficient, providing an easy and efficient method to indirectly evaluate interferometric coherence and serving as a basis in InSAR data processing. The results can provide pre-estimation of coherence information in Ningxia by optical images.
Article
Chemistry, Analytical
Junling Yin, Xiuqi Kong, Weiying Lin
Summary: This study introduces a biomarker based on tumor microenvironment viscosity, TBM-V, which can achieve cancer diagnosis, therapeutic effect tracking, and anticancer drug screening.
ANALYTICAL CHEMISTRY
(2021)
Article
Environmental Sciences
Seohyun Jang, Joo-Hyung Kim, Jihyun Kim
Summary: This study analyzed the spectral properties of plastic particles using mathematical methods, achieving the detection of plastic particles in water or ice. The identification precision of each plastic can reach up to 81% by compensating based on the spectral properties.
Article
Endocrinology & Metabolism
Yanfei Sun, Zhibin Wang, Zhiqiang Huang, Haofei Hu, Yong Han
Summary: This study found a positive and non-linear relationship between the TG/HDL-C ratio and the risk of diabetes in Chinese prediabetic patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Computer Science, Interdisciplinary Applications
R. Karthiga, K. Narasimhan, Rengarajan Amirtharajan
Summary: The diagnosis of breast cancer is challenging, and early detection can be achieved using image segmentation and artificial intelligence. The proposed method utilizes transfer learning and convolutional neural network to achieve high accuracy on different datasets.
MATHEMATICS AND COMPUTERS IN SIMULATION
(2022)
Article
Optics
Dusan Kojic, Roumiana Tsenkova, Masato Yasui
Summary: This paper introduces a lightweight operator that reduces the number of parameters in curve fitting, thereby decreasing model complexity and improving stability to initial conditions. By resolving overlapping bands and estimating bandwidth for overlapped features, this method outperforms similar approaches in terms of speed, flexibility, and interpretability.
JOURNAL OF QUANTITATIVE SPECTROSCOPY & RADIATIVE TRANSFER
(2022)
Article
Chemistry, Analytical
Salvatore A. Pullano, Antonino S. Fiorillo, Gianluca Barile, Vincenzo Stornelli, Giuseppe Ferri
Summary: The study introduces a novel approach for receiving ultrasounds in air using a piezopolymer sensor and VCII electronic interface, achieving a sensitivity level of about -100 dB without any filtration stage. The results are obtained using a commercially available AD844 for the second-generation voltage conveyor active device with a supply voltage of +/- 15 V.
Article
Chemistry, Analytical
Svitlana G. Ilchenko, Volodymyr V. Multian, Ruslan A. Lymarenko, Victor B. Taranenko, Salvatore A. Pullano, Antonino S. Fiorillo, Volodymyr Ya. Gayvoronsky
Summary: Polyvinylidene fluoride and its copolymers are widely used low-cost ferroelectric materials. The high biocompatibility, optical quality, chemical and mechanical durability of P(VDF-TrFE) make it attractive for designing effective coating layers for different diagnostic techniques. The nonlinear optical characterization of P(VDF-TrFE) coating films on a glass substrate showed advantages for multiphoton imaging and long-duration characterization of harmonic nanoparticles (HNPs) with improved analysis robustness by effectively protecting the glass surface.
Review
Medicine, Research & Experimental
Salvatore Andrea Pullano, Marta Greco, Maria Giovanna Bianco, Daniela Foti, Antonio Brunetti, Antonino S. Fiorillo
Summary: This review aims to present the importance of glucose monitoring devices and updated guidelines in managing diabetic patients. It discusses the technological and clinical advances in the field and proposes a roadmap for future development in glucose monitoring and patient management.
Article
Engineering, Biomedical
Salvatore A. Pullano, Maria Giovanna Bianco, Marta Greco, Daniela Mazzuca, Steven P. Nistico, Antonino S. Fiorillo
Summary: This study investigates the diagnosis of psoriasis through saliva profiling using Fourier Transform Infrared Spectroscopy and machine learning algorithms for automatic classification. The results demonstrate the potential of saliva analysis and multivariate analysis in the diagnosis and follow-up of inflammatory dermatopathies.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2022)
Article
Engineering, Electrical & Electronic
Salvatore Andrea Pullano, Venkata Deepa Kota, Karthik Kakaraparty, Antonino S. Fiorillo, Ifana Mahbub
Summary: In this paper, an optically unobtrusive dry electrode based on the iono-electric properties of zeolite is developed and proposed for continuous electrocardiogram (ECG) monitoring. The electrical and bio-electrical characterizations are evaluated for different types of electrodes, and the results show that certain parameters lead to the best performance.
IEEE SENSORS JOURNAL
(2022)
Article
Pharmacology & Pharmacy
Rocco Spagnuolo, Francesco Salvatore Iaquinta, Daniele Mauro, Ilenia Pantano, Stefano Dastoli, Saverio Naty, Cristina Cosco, Rosellina Margherita Mancina, Daniela Iacono, Emanuela Gaggiano, Annarita Ruggiero, Steven Paul Nistico, Francesco Ciccia, Rosa Daniela Grembiale, Doldo Patrizia
Summary: This study aimed to assess satisfaction with social roles and physical function alterations in patients with immune-mediated inflammatory diseases and identify associated characteristics. The results showed that these diseases have a negative impact on physical function and satisfaction with social roles. Gender and treatment were found to be independently associated factors.
REVIEWS ON RECENT CLINICAL TRIALS
(2022)
Article
Medicine, General & Internal
Marta Greco, Maria Mirabelli, Alessandro Salatino, Francesca Accattato, Vincenzo Aiello, Francesco S. Brunetti, Eusebio Chiefari, Salvatore A. Pullano, Antonino S. Fiorillo, Daniela P. Foti, Antonio Brunetti
Summary: This cross-sectional study aims to identify potential novel biomarkers for the early diagnosis of type 2 diabetes (T2D) by investigating the differential expression patterns of circulating microRNAs (miRNAs) in patients with impaired fasting glucose (IFG) and new-onset T2D. Out of the 372 analyzed miRNAs, 33 showed significantly different expression patterns in IFG and new-onset T2D patients compared to healthy controls. Nine miRNAs exhibited specific upregulation in new-onset T2D patients, suggesting their role as early biomarkers for progression from prediabetes to T2D.
Proceedings Paper
Engineering, Electrical & Electronic
Venkata Deepa Kota, Salvatore Andrea Pullano, Antonino S. Fiorillo, Ifana Mahbub
Summary: Long-term monitoring of vital signs is crucial for evaluating sporadic cardiac dysfunctions, and optically unobtrusive electrodes offer advantages of high transparency and ubiquitous health data acquisition. The study found that electrodes fabricated with zeolite 4A degrees exhibited a higher Signal-to-Noise Ratio (SNR), and increasing the diameter and decreasing the thickness of the electrode contributed to the improvement of SNR.
Proceedings Paper
Acoustics
Gianluca Barile, Salvatore A. Pullano, Antonino S. Fiorillo, Giuseppe Ferri
Summary: Ultrasonic transducers for in-air applications are limited by their narrow frequency band, but efforts have been made to overcome this limitation. The use of PVDF and VCII technology has been proposed to improve the transducers and electronic interfaces. Experimental results have shown that the transducers have interesting characteristics in terms of bandwidth and directionality, while the electronic interfaces provide a wide bandwidth even at higher gain levels.
2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS)
(2022)
Article
Biotechnology & Applied Microbiology
Salvatore Andrea Pullano, Gianmarco Marciano, Maria Giovanna Bianco, Giuseppe Oliva, Vincenzo Rania, Cristina Vocca, Erika Cione, Giovambattista De Sarro, Luca Gallelli, Pietro Romeo, Antonio La Gatta, Antonino S. Fiorillo
Summary: This study investigated the structural changes induced by high-intensity, low-frequency magnetic fields on pharmacological molecules. Clinical validation was conducted on patients with lower back pain using diamagnetic therapy with topical ketoprofen or KiOil. The results showed that both ketoprofen and KiOil experienced structural modifications, and the clinical treatment demonstrated significant pain relief.
BIOENGINEERING-BASEL
(2022)
Article
Biotechnology & Applied Microbiology
Giuseppe Oliva, Maria Giovanna Bianco, Antonino S. Fiorillo, Salvatore A. Pullano
Summary: Since sunlight is a readily available and clean energy source, the development of solar cells and improving their efficiency is an important topic. One limiting factor of photovoltaic cells is light reflection, which can be reduced by using anti-reflective coatings. In this study, anti-reflective coatings were deposited on commercial PV cells using two different types of zeolites. The results showed enhanced fill factors and improved performance, especially in the bands relevant to implantable medical devices. The proposed technique offers a simple and reliable deposition method for improving the efficiency of solar cells.
BIOENGINEERING-BASEL
(2022)
Proceedings Paper
Engineering, Electrical & Electronic
S. A. Pullano, M. Greco, D. P. Foti, A. Brunetti, A. S. Fiorillo
Summary: Cell culturing is a commonly used technique, with recent intensive research on cellular thermodynamics and the development of a dual pyroelectric sensor for thermal characterization of cultured cells. The dual sensor shows linear dependence on cell concentrations and effectively reduces the impact of common-mode signals, making it a promising tool for rapid lab-based applications.
2021 IEEE SENSORS APPLICATIONS SYMPOSIUM (SAS 2021)
(2021)
Proceedings Paper
Engineering, Electrical & Electronic
S. A. Pullano, M. Greco, S. Scalise, E. Parrotta, V Lucchino, G. Cuda, A. S. Fiorillo
Summary: Experimental results indicate that the pathological variant of NaV1.1 channel may lead to changes in the thermal conductivity of iPSCs, highlighting its potential impact on cellular function.
Review
Acoustics
Salvatore A. Pullano, Costantino Davide Critello, Maria Giovanna Bianco, Michele Menniti, Antonino S. Fiorillo
Summary: This article presents a review on the application and development of PVDF technology in the manufacturing of in-air ultrasonic transducers, which are widely used in medical robotics, sonar systems, and automation industry. The goal is to provide a comprehensive view on the development of such ultrasonic transducers, highlighting the constructive choices and the advantages/disadvantages.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2021)
Proceedings Paper
Health Care Sciences & Services
Giancluca Barile, Salvatore A. Pullano, Antonino S. Fiorillo, Giuseppe Ferri
Summary: The study introduces a biologically inspired ultrasonic transducer with wideband and directional characteristics for developing a broadband system in-air. It also utilizes spiral-shaped PVDF transducers and VCII electronic interfaces for generating and receiving ultrasounds with a bandwidth larger than 60 kHz.
2021 INTERNATIONAL CONFERENCE ON E-HEALTH AND BIOENGINEERING (EHB 2021), 9TH EDITION
(2021)
