The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease
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Title
The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease
Authors
Keywords
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Journal
CLINICAL SCIENCE
Volume 135, Issue 24, Pages 2667-2689
Publisher
Portland Press Ltd.
Online
2021-11-23
DOI
10.1042/cs20210735
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Note: Only part of the references are listed.- Lack of Evidence of ACE2 Expression and Replicative Infection by SARSCoV-2 in Human Endothelial Cells
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- (2021) Alessandra Amendola et al. CARDIOVASCULAR RESEARCH
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- (2021) Suzannah J. Rihn et al. PLOS BIOLOGY
- Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model
- (2021) Tingxuan Gu et al. Frontiers in Immunology
- SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2
- (2021) Yuyang Lei et al. CIRCULATION RESEARCH
- SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19
- (2021) Lize M. Grobbelaar et al. BIOSCIENCE REPORTS
- Spike protein of SARS‐CoV‐2 activates macrophages and contributes to induction of acute lung inflammation in male mice
- (2021) Xiaoling Cao et al. FASEB JOURNAL
- Coronary microvascular dysfunction pathophysiology in COVID‐19
- (2021) Jie Yin et al. MICROCIRCULATION
- The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2
- (2020) Liang Chen et al. CARDIOVASCULAR RESEARCH
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts
- (2020) Luka Nicin et al. EUROPEAN HEART JOURNAL
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
- (2020) Jun Lan et al. NATURE
- A serological assay to detect SARS-CoV-2 seroconversion in humans
- (2020) Fatima Amanat et al. NATURE MEDICINE
- Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
- (2020) Shutoku Matsuyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series
- (2020) Michael G Argenziano et al. BMJ-British Medical Journal
- Myocyte Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2 Mediated Myocarditis
- (2020) Nathan R. Tucker et al. CIRCULATION
- Pericyte alteration sheds light on micro-vasculopathy in COVID-19 infection
- (2020) Nathalie Cardot-Leccia et al. INTENSIVE CARE MEDICINE
- Kinetics and performance of the Abbott architect SARS-CoV-2 IgG antibody assay
- (2020) Fergus Hamilton et al. JOURNAL OF INFECTION
- Estimates of the severity of coronavirus disease 2019: a model-based analysis
- (2020) Robert Verity et al. LANCET INFECTIOUS DISEASES
- SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects
- (2020) Antoni G. Wrobel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein
- (2020) Andrew D. Davidson et al. Genome Medicine
- Severe COVID-19 is a Microvascular Disease
- (2020) Charles J. Lowenstein et al. CIRCULATION
- SARS-CoV-2 and the Possible Role of Raf/MEK/ERK Pathway in Viral Survival: Is This a Potential Therapeutic Strategy for COVID-19?
- (2020) Morteza Ghasemnejad-Berenji et al. PHARMACOLOGY
- Neuropilin-1 is a host factor for SARS-CoV-2 infection
- (2020) James L. Daly et al. SCIENCE
- Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein
- (2020) Christine Toelzer et al. SCIENCE
- The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice
- (2020) Elizabeth M. Rhea et al. NATURE NEUROSCIENCE
- The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier
- (2020) Tetyana P. Buzhdygan et al. NEUROBIOLOGY OF DISEASE
- Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
- (2020) Marthe Jøntvedt Jørgensen et al. Scientific Reports
- Human mesenchymal stromal cells do not express ACE2 and TMPRSS2 and are not permissive to SARS‐CoV ‐2 infection
- (2020) Maria A. Avanzini et al. Stem Cells Translational Medicine
- Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein
- (2020) Gerard J. Nuovo et al. Annals of Diagnostic Pathology
- Human Myocardial Pericytes: Multipotent Mesodermal Precursors Exhibiting Cardiac Specificity
- (2015) William C. W. Chen et al. STEM CELLS
- Function of CD147 in Atherosclerosis and Atherothrombosis
- (2015) Cuiping Wang et al. Journal of Cardiovascular Translational Research
- Expansion and Characterization of Neonatal Cardiac Pericytes Provides a Novel Cellular Option for Tissue Engineering in Congenital Heart Disease
- (2015) E. Avolio et al. Journal of the American Heart Association
- Isolation, bulk cultivation, and characterization of coronary microvascular pericytes: the second most frequent myocardial cell type in vitro
- (2011) Stephan Nees et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Human Adult Vena Saphena Contains Perivascular Progenitor Cells Endowed With Clonogenic and Proangiogenic Potential
- (2010) Paola Campagnolo et al. CIRCULATION
- CD147/EMMPRIN Acts as a Functional Entry Receptor for Measles Virus on Epithelial Cells
- (2010) A. Watanabe et al. JOURNAL OF VIROLOGY
- Peptide Mimicrying Between SARS Coronavirus Spike Protein and Human Proteins Reacts with SARS Patient Serum
- (2008) K.-Y. Hwa et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
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