A Quantitative Modeling and Simulation Framework to Support Candidate and Dose Selection of Anti‐SARS‐CoV‐2 Monoclonal Antibodies to Advance Bamlanivimab Into a First‐in‐Human Clinical Trial

Hybrid physiologically‐based pharmacokinetic model for remdesivir: Application to SARS‐CoV‐2

(2021) James M. Gallo   CTS-Clinical and Translational Science

Clinical Pharmacology Regulatory Sciences in Drug Development and Precision Medicine: Current Status and Emerging Trends

(2021) Qi Liu et al.   AAPS Journal

Industrial Perspective on the Benefits Realized from the FDA’s Model‐Informed Drug Development Paired Meeting Pilot Program

(2021) Gerald R. Galluppi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

(2021) Bryan E. Jones et al.   Science Translational Medicine

First in Human Study of Bamlanivimab in a Randomized Trial of Hospitalized Patients with COVID‐19

(2021) Peter Chen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

An interactive web-based dashboard to track COVID-19 in real time

(2020) Ensheng Dong et al.   LANCET INFECTIOUS DISEASES

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

Connecting hydroxychloroquine in vitro antiviral activity to in vivo concentration for prediction of antiviral effect: a critical step in treating COVID-19 patients

(2020) Jianghong Fan et al.   CLINICAL INFECTIOUS DISEASES

The global impact of the coronavirus pandemic

(2020) John Hiscott et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Open science takes on the coronavirus pandemic

(2020) Mark Zastrow   NATURE

Viral kinetics of SARS-CoV-2 over the preclinical, clinical, and postclinical period

(2020) Sukbin Jang et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19

(2020) Peter Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics

(2019) Sabue Mulangu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Getting Innovative Therapies Faster to Patients at the Right Dose: Impact of Quantitative Pharmacology Towards First Registration and Expanding Therapeutic Use

(2018) Satyaprakash Nayak et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics

(2018) Lindsay B. Avery et al.   mAbs

A Quasi-Steady-State Approximation to the Basic Target-Cell-Limited Viral Dynamics Model with a Non-Cytopathic Effect

(2018) Richard A. Cangelosi et al.   Frontiers in Microbiology

Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis

(2017) Satyawan B. Jadhav et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

PBPK modeling and simulation in drug research and development

(2016) Xiaomei Zhuang et al.   Acta Pharmaceutica Sinica B

Antibody biodistribution coefficients

(2013) Dhaval K. Shah et al.   mAbs

Pharmacokinetic and Pharmacodynamic Properties of Canakinumab, a Human Anti-Interleukin-1β Monoclonal Antibody

(2012) Abhijit Chakraborty et al.   CLINICAL PHARMACOKINETICS

Population Pharmacokinetics of Therapeutic Monoclonal Antibodies

(2010) Nathanael L. Dirks et al.   CLINICAL PHARMACOKINETICS

Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

(2010) Ron J. Keizer et al.   CLINICAL PHARMACOKINETICS