Relative Efficacy and Safety of Tanezumab for Osteoarthritis

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee

(2020) Sharon L. Kolasinski et al.   Arthritis & Rheumatology

Subcutaneous tanezumab 2.5 MG or 5 MG for patients with osteoarthritis of the knee or hip: onset and maintenance of efficacy over 24 weeks

(2020) F. Berenbaum et al.   OSTEOARTHRITIS AND CARTILAGE

Onset and maintenance of efficacy of subcutaneous tanezumab in patients with moderate to severe osteoarthritis of the knee or hip: A 16-week dose-titration study

(2020) Thomas J. Schnitzer et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Core and adjunctive interventions for osteoarthritis: efficacy and models for implementation

(2020) Jocelyn L. Bowden et al.   Nature Reviews Rheumatology

Targeting neurotrophic factors: Novel approaches to musculoskeletal pain

(2020) Anne-Marie Malfait et al.   PHARMACOLOGY & THERAPEUTICS

Therapeutic options for targeting inflammatory osteoarthritis pain

(2019) Philip G. Conaghan et al.   Nature Reviews Rheumatology

Effect of Tanezumab on Joint Pain, Physical Function, and Patient Global Assessment of Osteoarthritis Among Patients With Osteoarthritis of the Hip or Knee

(2019) Thomas J. Schnitzer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Onset and maintenance of efficacy of subcutaneous tanezumab in patients with moderate to severe osteoarthritis of the knee or hip

(2019) L. Bessette et al.   OSTEOARTHRITIS AND CARTILAGE

Safety and efficacy of subcutaneous tanezumab in patients with knee or hip osteoarthritis

(2018) Charles Birbara et al.   Journal of Pain Research

Long-Term Safety and Efficacy of Fulranumab in Patients With Moderate-to-Severe Osteoarthritis Pain: A Phase II Randomized, Double-Blind, Placebo-Controlled Extension Study

(2017) Panna Sanga et al.   Arthritis & Rheumatology

Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model

(2016) Timothy P LaBranche et al.   ANNALS OF THE RHEUMATIC DISEASES

When Is Osteonecrosis Not Osteonecrosis?: Adjudication of Reported Serious Adverse Joint Events in the Tanezumab Clinical Development Program

(2016) Marc C. Hochberg et al.   Arthritis & Rheumatology

Tanezumab for Patients with Osteoarthritis of the Knee: A Meta-Analysis

(2016) Shun-Li Kan et al.   PLoS One

Serious joint-related adverse events in randomized controlled trials of anti-nerve growth factor monoclonal antibodies

(2015) M.C. Hochberg   OSTEOARTHRITIS AND CARTILAGE

A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee

(2015) T.J. Schnitzer et al.   OSTEOARTHRITIS AND CARTILAGE

Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain

(2014) Thomas J Schnitzer et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and Safety of Intravenous Tanezumab for the Symptomatic Treatment of Osteoarthritis: 2 Randomized Controlled Trials versus Naproxen

(2014) E. F. Ekman et al.   JOURNAL OF RHEUMATOLOGY

Nerve safety of tanezumab, a nerve growth factor inhibitor for pain treatment

(2014) Mark T. Brown et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Tanezumab Reduces Osteoarthritic Hip Pain: Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial

(2013) Mark T. Brown et al.   ARTHRITIS AND RHEUMATISM

A phase III placebo- and oxycodone-controlled study of tanezumab in adults with osteoarthritis pain of the hip or knee

(2013) Egilius L.H. Spierings et al.   PAIN

Tanezumab Reduces Osteoarthritic Knee Pain: Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial

(2012) Mark T. Brown et al.   JOURNAL OF PAIN

Efficacy and safety of intravenous tanezumab in osteoarthritis hip and knee pain: comparison to placebo and naproxen in two phase III studies (NCT00830063 & NCT00863304)

(2011) E. Ekman et al.   JOURNAL OF PAIN

Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized, double-blind, dose-escalation, placebo-controlled study

(2011) H. Nagashima et al.   OSTEOARTHRITIS AND CARTILAGE

Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

(2010) Nancy E. Lane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE