Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model

Serious joint-related adverse events in randomized controlled trials of anti-nerve growth factor monoclonal antibodies

(2015) M.C. Hochberg   OSTEOARTHRITIS AND CARTILAGE

Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain

(2014) Thomas J Schnitzer et al.   ANNALS OF THE RHEUMATIC DISEASES

Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis

(2013) Sadaf Ashraf et al.   ANNALS OF THE RHEUMATIC DISEASES

Tanezumab Reduces Osteoarthritic Hip Pain: Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial

(2013) Mark T. Brown et al.   ARTHRITIS AND RHEUMATISM

A phase III placebo- and oxycodone-controlled study of tanezumab in adults with osteoarthritis pain of the hip or knee

(2013) Egilius L.H. Spierings et al.   PAIN

Efficacy and safety of tanezumab versus naproxen in the treatment of chronic low back pain

(2013) Alan J. Kivitz et al.   PAIN

Tanezumab Reduces Osteoarthritic Knee Pain: Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial

(2012) Mark T. Brown et al.   JOURNAL OF PAIN

Antagonism of Nerve Growth Factor-TrkA Signaling and the Relief of Pain

(2011) Patrick W. Mantyh et al.   ANESTHESIOLOGY

Efficacy and safety of intravenous tanezumab in osteoarthritis hip and knee pain: comparison to placebo and naproxen in two phase III studies (NCT00830063 & NCT00863304)

(2011) E. Ekman et al.   JOURNAL OF PAIN

Proof of Concept Trial of Tanezumab for the Treatment of Symptoms Associated With Interstitial Cystitis

(2011) R.J. Evans et al.   JOURNAL OF UROLOGY

Efficacy and safety of tanezumab in the treatment of chronic low back pain

(2011) Nathaniel Katz et al.   PAIN

Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

(2010) Nancy E. Lane et al.   NEW ENGLAND JOURNAL OF MEDICINE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rat

(2010) N. Gerwin et al.   OSTEOARTHRITIS AND CARTILAGE

A multiple-dose toxicity study of tanezumab in cynomolgus monkeys

(2010) Mark Zorbas et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis

(2010) D. A. Walsh et al.   RHEUMATOLOGY

The nerve of osteoarthritis pain

(2010) Jacqueline R. Hochman et al.   ARTHRITIS CARE & RESEARCH

Targeting Nerve Growth Factor in Pain

(2008) Judy J Watson et al.   BIODRUGS

Probing the binding mechanism and affinity of tanezumab, a recombinant humanized anti-NGF monoclonal antibody, using a repertoire of biosensors

(2008) Yasmina Noubia Abdiche et al.   PROTEIN SCIENCE