Atroposelective sp 3 C—H Coupling for Kinetic Resolution of Thioanilide Atropisomers

Chiral Pd-Catalyzed Enantioselective Syntheses of Various N–C Axially Chiral Compounds and Their Synthetic Applications

(2021) Osamu Kitagawa   ACCOUNTS OF CHEMICAL RESEARCH

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Synthesis of Axially Chiral Biaryl-2-amines by PdII -Catalyzed Free-Amine-Directed Atroposelective C−H Olefination

(2020) Bei-Bei Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From Pd(OAc)2 to Chiral Catalysts: The Discovery and Development of Bifunctional Mono-N-Protected Amino Acid Ligands for Diverse C–H Functionalization Reactions

(2020) Qian Shao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Atroposelective Ring Opening of Cyclic Diaryliodonium Salts with Bulky Anilines Controlled by a Chiral Cobalt(III) Anion

(2020) Zhenhua Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition Metal‐Catalyzed Enantioselective C–H Functionalization via Chiral Transient Directing Group Strategy

(2020) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Asymmetric Allylic C–H Functionalization: Mechanism, Stereo- and Regioselectivities, and Synthetic Applications

(2020) Pu-Sheng Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective Synthesis of Atropisomeric Anilides via Pd(II)-Catalyzed Asymmetric C–H Olefination

(2020) Qi-Jun Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Atropisomeric Anilides Synthesis via Cu-Catalyzed Intramolecular Adjacent C–N Coupling

(2019) Xiaozhong Fan et al.   ACS Catalysis

Cp*Co(III)/MPAA-Catalyzed Enantioselective Amidation of Ferrocenes Directed by Thioamides under Mild Conditions

(2019) Yan-Hua Liu et al.   ORGANIC LETTERS

Construction of N–C Axial Chirality through Atroposelective C–H Olefination of N-Arylindoles by Palladium/Amino Acid Cooperative Catalysis

(2019) Jitan Zhang et al.   ORGANIC LETTERS

Chiral 2-Aryl Ferrocene Carboxylic Acids for the Catalytic Asymmetric C(sp3)–H Activation of Thioamides

(2019) Daichi Sekine et al.   ORGANOMETALLICS

Pd-Catalyzed Atroposelective C–H Allylation and Alkenylation: Access to Enantioenriched Atropisomers Featuring Pentatomic Heteroaromatics

(2019) Hao-Ming Chen et al.   ORGANOMETALLICS

Thioketone-directed rhodium(I) catalyzed enantioselective C-H bond arylation of ferrocenes

(2019) Zhong-Jian Cai et al.   Nature Communications

Palladium-Catalyzed Enantioselective C−H Olefination of Diaryl Sulfoxides through Parallel Kinetic Resolution and Desymmetrization

(2018) Yu-Chao Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Enabled Enantioselective Csp3 -H Activation of Tetrahydroquinolines and Saturated Aza-Heterocycles by RhI

(2018) Steffen Greßies et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed Enantioselective Arylation of Unbiased Methylene C(sp3 )−H Bonds Enabled by a 2-Pyridinylisopropyl Auxiliary and Chiral Phosphoric Acids

(2018) Sheng-Yi Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Axially Chiral Dibenzazepinones via a Pd(0)-Catalyzed Atropo-enantioselective C-H Arylation

(2018) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atropisomerism in medicinal chemistry: challenges and opportunities

(2018) Sean T Toenjes et al.   Future Medicinal Chemistry

Enantioselective Bromocyclization of Tryptamines Induced by Chiral Co(III)-Complex-Templated Brønsted Acids under an Air Atmosphere

(2018) Kun Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective γ-C(sp3)–H Activation of Alkyl Amines via Pd(II)/Pd(0) Catalysis

(2018) Qian Shao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C(sp3)‒H bond activation by chiral transition metal catalysts

(2018) Tyler G. Saint-Denis et al.   SCIENCE

Atroposelective Catalytic Asymmetric Allylic Alkylation Reaction for Axially Chiral Anilides with Achiral Morita–Baylis–Hillman Carbonates

(2018) Shou-Lei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Atroposelective C−H Allylation through β-O Elimination: Diverse Synthesis of Axially Chiral Biaryls

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assembling a Hybrid Pd Catalyst from a Chiral Anionic CoIII Complex and Ligand for Asymmetric C(sp3 )-H Functionalization

(2018) Hua-Jie Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective C(sp3 )-H Amidation of Thioamides Catalyzed by a CobaltIII /Chiral Carboxylic Acid Hybrid System

(2018) Seiya Fukagawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Enantioselective C–H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands

(2017) Adam P. Smalley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted acids of anionic chiral Co(iii) complexes as catalysts for the stereoselective synthesis of cis-4-aminofuranobenzopyrans

(2017) Hua-Jie Jiang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

P(O)R2-Directed Enantioselective C–H Olefination toward Chiral Atropoisomeric Phosphine–Olefin Compounds

(2017) Shi-Xia Li et al.   ORGANIC LETTERS

Palladium(0)-catalyzed asymmetric C(sp3)–H arylation using a chiral binol-derived phosphate and an achiral ligand

(2017) Lei Yang et al.   Chemical Science

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

Enantioselective Oxetane Ring Opening with Chloride: Unusual Use of Wet Molecular Sieves for the Controlled Release of HCl

(2016) Wen Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Enantioselective Bidentate Auxiliary Directed Palladium-Catalyzed Benzylic C−H Arylation of Amines Using a BINOL Phosphate Ligand

(2016) Hao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective C−H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

(2016) Kai-Jiong Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of Benzylamines via Palladium(II)-Catalyzed C–H Cross-Coupling

(2016) Kai-Jiong Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective amine α-functionalization via palladium-catalysed C–H arylation of thioamides

(2016) Pankaj Jain et al.   Nature Chemistry

Catalytic Enantioselective Synthesis of N–C Axially Chiral Mebroqualone and Its Derivatives through Reductive Asymmetric Desymmetrization

(2016) Motohiro Hirai et al.   ORGANIC LETTERS

Sodium Salts of Anionic Chiral Cobalt(III) Complexes as Catalysts of the Enantioselective Povarov Reaction

(2015) Jie Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Enantioselective Synthesis of 3-Arylquinazolin-4(3H)-ones via Peptide-Catalyzed Atroposelective Bromination

(2015) Matthew E. Diener et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Asymmetric Arylation of C(sp3)–H Bonds of Aliphatic Amides: Controlling Enantioselectivity Using Chiral Phosphoric Amides/Acids

(2015) Shao-Bai Yan et al.   ORGANIC LETTERS

Chiral Counteranion Strategy for Asymmetric Oxidative C(sp3)H/C(sp3)H Coupling: Enantioselective α-Allylation of Aldehydes with Terminal Alkenes

(2014) Pu-Sheng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric synthesis of heteroaryl atropisomers via a gold-catalyzed cycloisomerization–amination cascade reaction

(2014) Rui Guo et al.   CHEMICAL COMMUNICATIONS

Asymmetric Synthesis of Atropisomeric Compounds with an N‒C Chiral Axis

(2014) Isao Takahashi et al.   ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL

Room-temperature enantioselective C–H iodination via kinetic resolution

(2014) Ling Chu et al.   SCIENCE

Pd(II)-Catalyzed Intermolecular Direct C–H Bond Iodination: An Efficient Approach toward the Synthesis of Axially Chiral Compounds via Kinetic Resolution

(2014) De-Wei Gao et al.   ACS Catalysis

Recent development of direct asymmetric functionalization of inert C–H bonds

(2013) Chao Zheng et al.   RSC Advances

Palladium-Catalyzed Enantioselective Allylic Alkylations through C-H Activation

(2012) Barry M. Trost et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Monodentate Phosphines and Bulky Carboxylic Acids: Cooperative Effects in Palladium-Catalyzed Enantioselective C(sp3)-H Functionalization

(2012) Tanguy Saget et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Planar Chiral Ferrocenes via Palladium-Catalyzed Direct Coupling with Arylboronic Acids

(2012) De-Wei Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric C(sp3)-H/C(Ar) coupling reactions. Highly enantio-enriched indolines via regiodivergent reaction of a racemic mixture

(2012) Dmitry Katayev et al.   Chemical Science

Fused Indolines by Palladium-Catalyzed Asymmetric CC Coupling Involving an Unactivated Methylene Group

(2011) Masafumi Nakanishi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective synthesis of 2-methyl indolines by palladium catalysed asymmetric C(sp3)–H activation/cyclisation

(2011) Saithalavi Anas et al.   CHEMICAL COMMUNICATIONS

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pd(II)-Catalyzed Enantioselective C–H Activation of Cyclopropanes

(2011) Masayuki Wasa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of Axially Chiral o-Iodoanilides by Phase-Transfer Catalyzed Alkylations

(2011) Seiji Shirakawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overview of the Mechanistic Work on the Concerted Metallation–Deprotonation Pathway

(2010) David Lapointe et al.   CHEMISTRY LETTERS

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity

(2009) Ramesh Giri et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Protonation of Itaconimides with Thiols and the Rotational Kinetics of the Axially Chiral CN Bond

(2009) Shishi Lin et al.   Chemistry-An Asian Journal

Enantiomerically enriched atropisomeric N,N′-diaryl ureas by oxidative kinetic resolution of their 2-sulfanyl derivatives

(2009) Jonathan Clayden et al.   TETRAHEDRON LETTERS

PdII-Catalyzed Enantioselective Activation of C(sp2)H and C(sp3)H Bonds Using Monoprotected Amino Acids as Chiral Ligands

(2008) Bing-Feng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION