Synthesis of Fluorinated Imidazole[4,5 f ][1,10]phenanthroline Derivatives as Potential Inhibitors of Liver Cancer Cell Proliferation by Inducing Apoptosis via DNA Damage

Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers

(2020) Qiong Wu et al.   BIOORGANIC CHEMISTRY

Design, synthesis and biological evaluation of artemisinin derivatives containing fluorine atoms as anticancer agents

(2018) Shu Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent advances of imidazole-containing derivatives as anti-tubercular agents

(2018) Yi-Lei Fan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and the interaction of 2-(1 H -pyrazol-4-yl)-1 H -imidazo[4,5-f][1,10]phenanthrolines with telomeric DNA as lung cancer inhibitors

(2017) Jiachun Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

DNA Strand Breaks in Mitotic Germ Cells of Caenorhabditis elegans Evaluated by Comet Assay

(2016)   MOLECULES AND CELLS

Experimental and theoretical investigations on spectroscopic properties of the imidazole-fused phenanthroline and its derivatives

(2016) Rongfeng Zhong et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agent inhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells

(2015) Ni Zhen et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

miR-25 Modulates Invasiveness and Dissemination of Human Prostate Cancer Cells via Regulation of αv- and α6-Integrin Expression

(2015) E. Zoni et al.   CANCER RESEARCH

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions

(2015) Monika Gaba et al.   MEDICINAL CHEMISTRY RESEARCH

cis and trans Isomers distinguished by imidazole N-alkylation after Debus-Radziszewski reaction starting from 2,7-di-tert-butyl-pyrene-4,5,9,10-tetraone

(2015) Bin-Bin Ma et al.   TETRAHEDRON

Microwave-assisted synthesis of phenanthroimidazole derivatives as stabilizer of c-myc G-quadruplex DNA

(2014) Siyan Liao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Advantage of the N-Alkylation Strategy for Retaining the Molecular Planarity for Oligothiophene/Imidazole/1,10-Phenanthroline-Based Heterocyclic Semiconducting and Fluorescent Compounds

(2014) Yu-Xin Peng et al.   Chemistry-An Asian Journal

Design, synthesis and biological evaluation of novel hybrid compounds of imidazole scaffold-based 2-benzylbenzofuran as potent anticancer agents

(2013) Xue-Quan Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Microwave-assisted synthesis of arene ruthenium(II) complexes that induce S-phase arrest in cancer cells by DNA damage-mediated p53 phosphorylation

(2013) Qiong Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry

(2013) Ling Zhang et al.   MEDICINAL RESEARCH REVIEWS

Design, synthesis and vasodilative activity of tanshinone IIA derivatives

(2012) Yue-Feng Bi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

Halogen bonding for rational drug design and new drug discovery

(2012) Yunxiang Lu et al.   Expert Opinion on Drug Discovery

Imidazole as an anti-epileptic: an overview

(2012) Rahul Mishra et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis and biological evaluation of benzo[d]imidazole derivatives as potential anti-cancer agents

(2011) Hamad M. Alkahtani et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New Heteroleptic Bis-Phenanthroline Copper(I) Complexes with Dipyridophenazine or Imidazole Fused Phenanthroline Ligands: Spectral, Electrochemical, and Quantum Chemical Studies

(2011) Yann Pellegrin et al.   INORGANIC CHEMISTRY

1,5-Diarylimidazoles with strong inhibitory activity against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells

(2010) Haiyan Che et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

First Selective CYP11B1 Inhibitors for the Treatment of Cortisol-Dependent Diseases

(2010) Ulrike E. Hille et al.   ACS Medicinal Chemistry Letters

Fluorine in medicinal chemistry: a century of progress and a 60-year retrospective of selected highlights

(2009) Robert Filler et al.   Future Medicinal Chemistry

Halogen BondingA Novel Interaction for Rational Drug Design?

(2009) Yunxiang Lu et al.   JOURNAL OF MEDICINAL CHEMISTRY