Article
Engineering, Biomedical
Wen Li, Yanli Bai, Jiasong Cao, Shan Gao, Pan Xu, Guowei Feng, Lichen Wang, Hongjun Wang, Deling Kong, Meng Fan, Jun Zhang, Meifeng Zhu
Summary: This study demonstrates the fabrication of highly inter-connected ioECM scaffolds, which improve the therapeutic effect of stem cell therapy in a limb ischemic model by enhancing stem cell survival, viability, and paracrine activities. The research provides reference value for the design and fabrication of ECM-based biomaterials for cell transplantation.
ACTA BIOMATERIALIA
(2021)
Article
Materials Science, Multidisciplinary
Dachuan Liu, Li Dong, Huan Wang, Jianzhong Bai, Jiaxu Shi, Weicheng Chen, Hongji Yan, Bin Li, Heng Sun, Song Chen
Summary: This study fabricated a biomimetic scaffold with good osteogenic properties through the mineralization of Fe-ACP, using ice-templated freeze-casting. In vitro studies showed that the mineralized scaffold had favorable biocompatibility and osteogenic properties. In vivo experiments demonstrated that the scaffold promoted bone regeneration by enhancing early osteogenesis and angiogenesis.
MATERIALS & DESIGN
(2023)
Article
Pharmacology & Pharmacy
Islam A. Arida, Isra H. Ali, Maha Nasr, Ibrahim M. El-Sherbiny
Summary: This review article discusses the importance of nanofiber scaffolds in wound healing for skin tissues, highlighting the various parameters affecting the electrospinning process and the incorporation of bioactive molecules for improved bioactivity and efficiency.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Biomedical
Vincent Fitzpatrick, Zaira Martin-Moldes, Anna Deck, Ruben Torres-Sanchez, Anne Valat, Dana Cairns, Chunmei Li, David L. Kaplan
Summary: The study aimed to use functionalized 3D-printed scaffolds for bone regeneration, incorporating silk-hydroxyapatite bone cements and various growth factors. Functionalities were assessed through cellular differentiation, migration, and proliferation, identifying synergistic effects among the growth factors.
Review
Anatomy & Morphology
Chinmaya Mahapatra, Prasoon Kumar, Manash K. Paul, Awanish Kumar
Summary: Current tissue engineering strategies in bone repair and regeneration have limitations, thus there is a need to develop fully functional vascularized bone tissue. Angiogenesis plays a crucial role in providing oxygen, nutrients, cell migration, and biological factors for bone tissue. To address the complex relationship between angiogenesis and bone formation, current research focuses on biomaterial development to induce neovascularization and angiogenesis.
Article
Biotechnology & Applied Microbiology
Xiaoyu Wu, Su Ni, Ting Dai, Jingyan Li, Fang Shao, Chun Liu, Jiafeng Wang, Shijie Fan, Yadong Tan, Linxiang Zhang, Qiting Jiang, Hongbin Zhao
Summary: Researchers developed a PCL/Gelatin composite electrospun membrane with bubble-shaped nanofibrous structures, which improved biomineralization ability by increasing surface roughness and promoting mineralization. The membrane exhibited excellent cell compatibility and adhesion, and it effectively promoted vascularization and bone regeneration. The sustained-release of tetramethylpyrazine showed excellent drug release efficiency.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Polymer Science
Ponrasu Thangavel, Hemalatha Kanniyappan, Sudip Chakraborty, Shipra Chaudhary, Aadinath Wallepure, Vignesh Muthuvijayan
Summary: Biomimetic scaffolds were prepared using konjac glucomannan (KGM) and silk fibroin (SF), which were cross-linked with citric acid and lyophilized to obtain fibrous structures. The KGM/SF scaffolds exhibited improved thermal stability, porous morphology, and biodegradable nature. They also showed enhanced compression strength and demonstrated biocompatibility, cell viability, and vascularization efficacy in tissue engineering and biomedical applications.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Engineering, Biomedical
Ying Wang, Ranjith Kumar Kankala, Caiwen Ou, Aizheng Chen, Zhilu Yang
Summary: This review focuses on the application and advantages of hydrogels in tissue vascularization, including the creation of highly complex three-dimensional tissues and organs, tunable physical properties, and high similarity to physiological environments. Furthermore, the utilization of hydrogel-based vascularized tissues in various applications such as tissue regeneration, drug screening, and organ-on-chips is discussed.
BIOACTIVE MATERIALS
(2022)
Article
Engineering, Biomedical
Chen Qin, Hongjian Zhang, Lei Chen, Meng Zhang, Jingge Ma, Hui Zhuang, Zhiguang Huan, Yin Xiao, Chengtie Wu
Summary: To achieve regeneration of highly vascularized and innervated tissues, a pre-angiogenic cell-laden scaffold with durable angiogenic functions is prepared. The scaffold supports long-term cell survival and growth, and exhibits durable angiogenic capability both in vitro and in vivo. The pre-angiogenic scaffolds can induce the neurogenetic differentiation and osteogenic differentiation, and may represent the future direction of biomaterials for complex tissue/organ regeneration.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Biomedical
Ioannis Eugenis, Di Wu, Thomas A. Rando
Summary: The paper discusses tissue engineering strategies for VML, including cell therapy, scaffold design, and bioactive factor delivery. It also addresses the limitations of current advanced technologies and the prospects of tissue-engineered bioconstructs for muscle regeneration and functional recovery following VML.
Article
Nanoscience & Nanotechnology
Matthias Schumacher, Pamela Habibovic, Sabine van Rijt
Summary: The slow and disorganized formation of a functional vascular network in large bone defect regeneration can cause delayed healing or implant failure. This study introduces a promising strategy by immobilizing the pro-angiogenic growth factor VEGF on nanosized bioactive glass particles using a binding peptide, which can induce angiogenesis and overcome the problem of insufficient neovascularization.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Cell Biology
Yahui Wang, Yong Xu, Guangdong Zhou, Yu Liu, Yilin Cao
Summary: In tissue engineering applications, an acellular dermal matrix (ADM) has been found to be more suitable for cartilage regeneration compared to an acellular cartilaginous matrix (ACM). ADM scaffolds exhibited better cell adhesion rate, more homogeneous chondrocyte distribution, and neocartilage formation. Subcutaneous implantation in a goat showed that ADM achieved more stable and matured cartilage.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Lin Zhang, Yunsheng Dong, Yufei Liu, Xiangsheng Liu, Zhitao Wang, Jinpeng Wan, Xinyi Yu, Shufang Wang
Summary: Multifunctional composite scaffolds have potential applications in the treatment of periodontal diseases, promoting bone regeneration and preventing fibrous tissue infiltration into bone defects.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Xiaocheng Wang, Yunru Yu, Chaoyu Yang, Luoran Shang, Yuanjin Zhao, Xian Shen
Summary: In this study, a responsive MX-HF scaffold is proposed to improve skin flap survival by promoting vascularization and skin flap regeneration. The scaffold demonstrates near-infrared responsiveness through the photothermal conversion capacity of MXene nanosheets and the temperature-responsive ability of poly(NIPAM) hydrogels, facilitating cell penetration into scaffold channels. Additionally, controlled delivery of vascular endothelial growth factor (VEGF) in the scaffold enhances angiogenesis.
Review
Biochemistry & Molecular Biology
Sadia Perveen, Daniela Rossin, Emanuela Vitale, Rachele Rosso, Roberto Vanni, Caterina Cristallini, Raffaella Rastaldo, Claudia Giachino
Summary: Myocardial infarction is a leading cause of heart-related deaths worldwide, and the potential of acellular scaffolds in treating MI is significant, as they can improve cardiac regeneration, limit adverse LV remodelling, and enhance heart function recovery.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Instruments & Instrumentation
Biplab Sarkar, Zain Siddiqui, Ka Kyung Kim, Peter K. Nguyen, Xavier Reyes, Trevor J. McGill, Vivek A. Kumar
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2020)
Article
Engineering, Environmental
Biplab Sarkar, Xiaotang Ma, Agnieszka Agas, Zain Siddiqui, Patricia Iglesias-Montoro, Peter K. Nguyen, Ka Kyung Kim, James Haorah, Vivek A. Kumar
Summary: This study demonstrates the potential of a self-assembling peptide containing an ependymin mimic to slow down acute glutamate-mediated excitotoxicity experienced by neurons and support neuronal survival. The biomimetic matrix can conform to intracranial damaged sites and has shear-responsive rheological properties.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Engineering, Biomedical
Zain Siddiqui, Biplab Sarkar, Ka-Kyung Kim, Nurten Kadincesme, Reshma Paul, Arjun Kumar, Yoshifumi Kobayashi, Abhishek Roy, Marwa Choudhury, Jian Yang, Emi Shimizu, Vivek A. Kumar
Summary: The study demonstrates the potential of acellular self-assembling peptide hydrogels in promoting tissue revascularization and soft tissue regeneration after endodontic treatment. The hydrogels show promise in guiding the development of neovasculature and tissue deposition, providing a scaffold for soft tissue regeneration in vivo.
ACTA BIOMATERIALIA
(2021)
Review
Biotechnology & Applied Microbiology
Natalie G. Kozan, Mrunmayi Joshi, Sydnee T. Sicherer, Jonathan M. Grasman
Summary: This article reviews the methods and materials used for fabricating porous biomaterial scaffolds for skeletal muscle regeneration. It discusses the current state of skeletal muscle tissue engineering and provides guidelines for scaffold fabrication based on functional requirements.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Pharmacology & Pharmacy
KaKyung Kim, Aryan Mahajan, Kamiya Patel, Shareef Syed, Amanda M. Acevedo-Jake, Vivek A. Kumar
Summary: This article discusses the challenges faced by diabetic patients in the wound healing process, including chronic inflammation, delayed healing responses, and current classification and treatment options for diabetic foot ulcers. Furthermore, it introduces the latest treatment strategies, such as using bioactive hydrogels to accelerate the healing of chronic wounds.
ADVANCED THERAPEUTICS
(2021)
Article
Nanoscience & Nanotechnology
Kaytlyn M. Crowe, Zain Siddiqui, Victoria Harbour, KaKyung Kim, Shareef Syed, Reshma Paul, Abhishek Roy, Ruhi Naik, Kayla Mitchell, Aryan Mahajan, Biplab Sarkar, Vivek A. Kumar
ACS APPLIED BIO MATERIALS
(2020)
Article
Nanoscience & Nanotechnology
Victoria Harbour, Candice Casillas, Zain Siddiqui, Biplab Sarkar, Sreya Sanyal, Peter Nguyen, Ka Kyung Kim, Abhishek Roy, Patricia Iglesias-Montoro, Saloni Patel, Frank Podlaski, Peter Tolias, William Windsor, Vivek Kumar
ACS APPLIED BIO MATERIALS
(2020)
Review
Engineering, Biomedical
Bryan J. Pfister, Jonathan M. Grasman, Joseph R. Loverde
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2020)
Article
Materials Science, Biomaterials
Ka-Kyung Kim, Zain Siddiqui, Manali Patel, Biplab Sarkar, Vivek A. Kumar
JOURNAL OF MATERIALS CHEMISTRY B
(2020)
Article
Engineering, Environmental
Xinping Zhang, Yuxin Guo, Xiaoyang Liu, Shun-Yu Wu, Ya-Xuan Zhu, Shao-Zhe Wang, Qiu-Yi Duan, Ke-Fei Xu, Zi-Heng Li, Xiao-Yu Zhu, Guang-Yu Pan, Fu-Gen Wu
Summary: This study develops a nanotrigger HCFT for simultaneous photodynamic therapy and light-triggered ferroptosis therapy. The nanotrigger can relieve tumor hypoxia, induce enhanced photodynamic reaction, and facilitate the continuation of Fenton reaction, ultimately leading to lethal ferroptosis in tumor cells.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Olumide Bolarinwa Ayodele, Toyin Daniel Shittu, Olayinka S. Togunwa, Dan Yu, Zhen-Yu Tian
Summary: This study focused on the semihydrogenation of acetylene in an ethylene-rich stream using two alloyed Pt catalysts PtCu and PtCo. The PtCu catalyst showed higher activity and ethylene yield compared to PtCo due to its higher unoccupied Pt d-orbital density. This indicates that alloying Pt with Cu is more promising for industrial relevant SHA catalyst.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Guowei Chen, Wen-Cheng Chen, Yaozu Su, Ruicheng Wang, Jia-Ming Jin, Hui Liang, Bingxue Tan, Dehua Hu, Shaomin Ji, Hao-Li Zhang, Yanping Huo, Yuguang Ma
Summary: This study proposes an intramolecular dual-locking design for organic luminescent materials, achieving high luminescence efficiency and performance for deep-blue organic light-emitting diodes. The material also exhibits unique mechanochromic luminescence behavior and strong fatigue resistance.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Joren van Stee, Gregory Hermans, Jinu Joseph John, Koen Binnemans, Tom Van Gerven
Summary: This work presents a continuous solvent extraction method for the separation of cobalt and nickel in a millifluidic system using Cyphos IL 101 (C101) as the extractant. The optimal conditions for extraction performance and solvent properties were determined by investigating the effects of channel length, flow rate, and temperature. The performance of a developed manifold structure was compared to a single-channel system, and excellent separation results were achieved. The continuous separation process using the manifold structure resulted in high purity cobalt and nickel products.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Yan Xu, Jingai Jiang, Xinyi Lv, Hui Li, Dongliang Yang, Wenjun Wang, Yanling Hu, Longcai Liu, Xiaochen Dong, Yu Cai
Summary: A programmed gas release nanoparticle was developed to address the challenges in treating diabetic infected wounds. It effectively removes drug-resistant pathogens and remodels the wound microenvironment using NO and H2S. The nanoparticle can eliminate bacteria and promote wound healing through antibacterial and anti-inflammatory effects.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Tong Xia, Zhilin Xi, Lianquan Suo, Chen Wang
Summary: This study investigated a highly efficient coal dust suppressant with low initial viscosity and high adhesion-solidification properties. The results demonstrated that the dust suppressant formed a network of multiple hydrogen bonding cross-linking and achieved effective adhesion and solidification of coal dust through various chemical reactions.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Jinzhi Cai, Zhenshan Li
Summary: A density functional theory-based rate equation was developed to predict the gas-solid reaction kinetics of CaO carbonation with CO2 in calcium looping. The negative activation energy of CaO carbonation close to equilibrium was accurately predicted through experimental validation.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Jianxiong Chen, Fuhao Ren, Ningning Yin, Jie Mao
Summary: This study presents an economically efficient and easily implementable surface modification approach to enhance the high-temperature electrical insulation and energy storage performance of polymer dielectrics. The self-assembly of high-insulation-performance boron nitride nanosheets (BNNS) on the film surface through electrostatic interactions effectively impedes charge injection from electrodes while promoting charge dissipation and heat transfer.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Zijian Li, Zhaohui Yang, Shao Wang, Hongxia Luo, Zhimin Xue, Zhenghui Liu, Tiancheng Mu
Summary: This study reports a strategy for upgrading polyester plastics into value-added chemicals using electrocatalytic methods. By inducing the targeted transfer of *OH species, polyethylene terephthalate was successfully upgraded into potassium diformate with high purity. This work not only develops an excellent electrocatalyst, but also provides guidance for the design of medium entropy metal oxides.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Navneet Singh Shekhawat, Surendra Kumar Patra, Ashok Kumar Patra, Bamaprasad Bag
Summary: This study primarily focuses on developing a sulphur dyeing process at room temperature using bacterial Lysate, which is environmentally friendly, energy and cost effective, and sustainable. The process shows promising improvements in dye uptake and fastness properties.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Dengjia Shen, Hongyang Ma, Madani Khan, Benjamin S. Hsiao
Summary: This study developed cationic PVC nanofibrous membranes with high filtration and adsorption capability for the removal of bacteria and hexavalent chromium ions from wastewater. The membranes demonstrated remarkable performance in terms of filtration efficiency and maximum adsorption capacity. Additionally, modified nanofibrous membranes were produced using recycled materials and showed excellent retention rates in dynamic adsorption processes.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Xiaoyan Wang, Zhikun Wang, Ben Jia, Chunling Li, Shuangqing Sun, Songqing Hu
Summary: Inspired by photosystem II, self-supported Fe-doped NiCoP nanowire arrays modified with carboxylate were constructed to boost industrial-level overall water splitting by employing the concerted proton-coupled electron transfer mechanism. The introduction of Fe and carboxyl ligand led to improved catalytic activity for HER and OER, and NCFCP@NF exhibited long-term durability for overall water splitting.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Pengyao Yu, Ge Yang, Yongming Chai, Lubomira Tosheva, Chunzheng Wang, Heqing Jiang, Chenguang Liu, Hailing Guo
Summary: Thin LTA zeolite membranes were prepared through secondary growth of nano LTA seeds in a highly reactive gel, resulting in membranes with superior permeability and selectivity in gas separation applications.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Baiqin Zhou, Huiping Li, Ziyu Wang, Hui Huang, Yujun Wang, Ruichun Yang, Ranran Huo, Xiaoyan Xu, Ting Zhou, Xiaochen Dong
Summary: The use of machine learning to predict the performance of specific adsorbents in phosphate adsorption shows great promise in saving time and revealing underlying mechanisms. However, the small size of the dataset and insufficient detailed information limits the model training process and the accuracy of results. To address this, the study employs a fuzzing strategy that replaces detailed numeric information with descriptive text messages on the physiochemical properties of adsorbents. This strategy allows the recovery of discarded samples with limited information, leading to accurate prediction of adsorption amount, capacity, and kinetics. The study also finds that phosphate uptake by adsorbents is generally through physisorption, with some involvement of chemisorption. The framework established in this study provides a practical approach for quickly predicting phosphate adsorption performance in urgent scenarios, using easily accessible information.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Paula Alejandra Lamprea Pineda, Joren Bruneel, Kristof Demeestere, Lisa Deraedt, Tex Goetschalckx, Herman Van Langenhove, Christophe Walgraeve
Summary: This study evaluates the use of four esterified fatty acids and three vegetable oils as absorption liquids for hydrophobic VOCs. The experimental results show that isopropyl myristate is the most efficient liquid for absorbing the target VOCs.
CHEMICAL ENGINEERING JOURNAL
(2024)