Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition

Design, Synthesis, and Dual Evaluation of Quinoline and Quinolinium Iodide Salt Derivatives as Potential Anticancer and Antibacterial Agents

(2020) Guofan Jin et al.   ChemMedChem

Synthesis of some 5‐arylidene‐2‐(4‐acetamidophenylimino)‐thiazolidin‐4‐one derivatives and exploring their breast anticancer activity

(2020) Hana M. A. Abumelha et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Quinoline‐1,3‐Oxazole Hybrids: Syntheses, Anticancer Activity and Molecular Docking Studies

(2020) Shailesh R. Shah et al.   ChemistrySelect

Synthesis and colon anticancer activity of some novel thiazole/-2-quinolone derivatives

(2020) Ashraf A. Aly et al.   JOURNAL OF MOLECULAR STRUCTURE

Design, synthesis, and anticancer activity of novel 4-thiazolidinone-phenylaminopyrimidine hybrids

(2020) Aslı Türe et al.   MOLECULAR DIVERSITY

A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications

(2020) Nagaraju Kerru et al.   MOLECULES

Quinoline‐based promising anticancer and antibacterial agents, and some metabolic enzyme inhibitors

(2020) Salih Ökten et al.   ARCHIV DER PHARMAZIE

Triaryl dicationic DNA minor-groove binders with antioxidant activity display cytotoxicity and induce apoptosis in breast cancer

(2020) Mohamed S. Nafie et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches

(2020) Eman S. Tantawy et al.   JOURNAL OF MOLECULAR STRUCTURE

Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance

(2020) Qing-Hai Li et al.   Gastroenterology Report

Antimicrobial and antiproliferative activities of novel synthesized 6‐(quinolin‐2‐ylthio) pyridine derivatives with molecular docking study as multi‐targeted JAK2/STAT3 inhibitors

(2020) Mohamed S. Nafie et al.   Chemical Biology & Drug Design

Discovery of novel pyrazolo[3,4-b]pyridine scaffold-based derivatives as potential PIM-1 kinase inhibitors in breast cancer MCF-7 cells

(2020) Mohamed S. Nafie et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of 4-((4-(4-(3-(2-(2,6-difluorophenyl)-4-oxothiazolidin-3-yl)ureido)-2-fluorophenoxy)-6-methoxyquinolin-7-yl)oxy)-N,N-diethylpiperidine-1-carboxamide as kinase inhibitor for the treatment of colorectal cancer

(2020) Yuting Zhou et al.   BIOORGANIC CHEMISTRY

Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications

(2019) Sonam Nirwan et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis, Characterization, Molecular Docking, and Anticancer Evaluation of 4‐Thiazolidinone Analogues

(2019) Md Mushtaque et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Enhanced Proapoptotic Effects of Water Dispersed Complexes of 4-Thiazolidinone-Based Chemotherapeutics with a PEG-Containing Polymeric Nanocarrier

(2019) L. Kobylinska et al.   Nanoscale Research Letters

Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents

(2019) Mohamed Hisham et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

7-Chloroquinoline-1,2,3-triazoyl carboxamides induce cell cycle arrest and apoptosis in human bladder carcinoma cells

(2019) Mariana S. Sonego et al.   INVESTIGATIONAL NEW DRUGS

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

Benzothiazole derivatives as anticancer agents

(2019) Ali Irfan et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Screening of different drug design tools to predict the mode of action of steroidal derivatives as anti-cancer agents

(2019) Mohamed S. Nafie et al.   STEROIDS

New Quinoline Based Sulfonamide Derivatives : Cytotoxic and Apoptotic Activity Evaluation Against Pancreas Cancer Cells

(2018) Leyla Yurttas et al.   Anti-Cancer Agents in Medicinal Chemistry

Mitochondria-targeting indolizino[3,2- c ]quinolines as novel class of photosensitizers for photodynamic anticancer activity

(2018) Soonbum Kwon et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Biologically active quinoline and quinazoline alkaloids part II

(2018) Xiao-Fei Shang et al.   MEDICINAL RESEARCH REVIEWS

Synthesis and Antiproliferative Activity of Novel 2-Substituted N-Methylated Benzimidazoles and Tetracyclic Benzimidazo [1,2-a]Quinolines

(2018) Nataša Perin et al.   POLYCYCLIC AROMATIC COMPOUNDS

Synthesis and anti-proliferative activity of some new quinoline based 4,5-dihydropyrazoles and their thiazole hybrids as EGFR inhibitors

(2018) Riham F. George et al.   BIOORGANIC CHEMISTRY

Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents

(2017) Ali Erguc et al.   Letters in Drug Design & Discovery

Design, synthesis and biological evaluation of new 4-(4-substituted-anilino)quinoline derivatives as anticancer agents

(2017) Khaled R. A. Abdellatif et al.   MEDICINAL CHEMISTRY RESEARCH

Biologically active quinoline and quinazoline alkaloids part I

(2017) Xiao-Fei Shang et al.   MEDICINAL RESEARCH REVIEWS

5-Ene-4-thiazolidinones induce apoptosis in mammalian leukemia cells

(2016) Julia Senkiv et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel 5-arylidenethiazolidinones with apoptotic properties via a three component reaction using piperidine as a bifunctional reagent

(2016) Chandramohan Bathula et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Comprehensive review on current developments of quinoline-based anticancer agents

(2016) Shweta Jain et al.   Arabian Journal of Chemistry

New arylated benzo[h]quinolines induce anti-cancer activity by oxidative stress-mediated DNA damage

(2016) Dharmendra K. Yadav et al.   Scientific Reports

A Review on the Synthesis and Anti-cancer Activity of 2-substituted Quinolines

(2015) Kaalin Gopaul et al.   Anti-Cancer Agents in Medicinal Chemistry

BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model

(2015) Chien-Chih Chiu et al.   BMC CANCER

A review on anticancer potential of bioactive heterocycle quinoline

(2015) Obaid Afzal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Novel Ethyl (substituted)phenyl-4-oxothiazolidin-3-yl)-1-ethyl-4-oxo-1,4-dihydroquinoline-3-Carboxylates as Potential Anticancer Agents

(2014) Victor Facchinetti et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synergistic action by multi-targeting compounds produces a potent compound combination for human NSCLC both in vitro and in vivo

(2014) C Zhang et al.   Cell Death & Disease

PQ1, a quinoline derivative, induces apoptosis in T47D breast cancer cells through activation of caspase-8 and caspase-9

(2013) Ying Ding et al.   APOPTOSIS

Study on potential antitumor mechanism of quinoline-based silver(I) complexes: Synthesis, structural characterization, cytotoxicity, cell cycle and caspase-initiated apoptosis

(2013) Yu-Lan Li et al.   INORGANIC CHEMISTRY COMMUNICATIONS

Synthesis of New 4-Thiazolidinone-, Pyrazoline-, and Isatin-Based Conjugates with Promising Antitumor Activity

(2012) Dmytro Havrylyuk et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quinoline as a Privileged Scaffold in Cancer Drug Discovery

(2011) V. R. Solomon et al.   CURRENT MEDICINAL CHEMISTRY

A novel DNA intercalator, 8-methoxy pyrimido[4′,5′:4,5]thieno (2,3-b)quinoline-4(3H)-one induces apoptosis in cancer cells, inhibits the tumor progression and enhances lifespan in mice with tumor

(2011) Sheetal Sharma et al.   MOLECULAR CARCINOGENESIS

Design, synthesis and biological evaluation of thiazolidinone derivatives as potential EGFR and HER-2 kinase inhibitors

(2009) Peng-Cheng Lv et al.   BIOORGANIC & MEDICINAL CHEMISTRY