Antimicrobial and antiproliferative activities of novel synthesized 6‐(quinolin‐2‐ylthio) pyridine derivatives with molecular docking study as multi‐targeted JAK2/STAT3 inhibitors

Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway

(2020) Shahad W. Kattan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Triaryl dicationic DNA minor-groove binders with antioxidant activity display cytotoxicity and induce apoptosis in breast cancer

(2020) Mohamed S. Nafie et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches

(2020) Eman S. Tantawy et al.   JOURNAL OF MOLECULAR STRUCTURE

NO-releasing STAT3 inhibitors suppress BRAF-mutant melanoma growth

(2019) Tamer S. Kaoud et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Differential expression of miRNAs regulating NF-κB and STAT3 crosstalk during colitis-associated tumorigenesis

(2019) Sherien M. El-Daly et al.   MOLECULAR AND CELLULAR PROBES

Synthesis, molecular modeling and anti-cancer evaluation of a series of quinazoline derivatives

(2019) Ahmed I. Khodair et al.   CARBOHYDRATE RESEARCH

Screening of different drug design tools to predict the mode of action of steroidal derivatives as anti-cancer agents

(2019) Mohamed S. Nafie et al.   STEROIDS

1,3,4-oxadiazole/chalcone hybrids: Design, synthesis, and inhibition of leukemia cell growth and EGFR, Src, IL-6 and STAT3 activities

(2018) Marwa Ali A. Fathi et al.   BIOORGANIC CHEMISTRY

New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity

(2018) Samar H. Abbas et al.   BIOORGANIC CHEMISTRY

Mesenchymal stem cells therapy enhances the efficacy of pregabalin and prevents its motor impairment in paclitaxel-induced neuropathy in rats: Role of Notch1 receptor and JAK/STAT signaling pathway

(2018) Khaled F. Al-Massri et al.   BEHAVIOURAL BRAIN RESEARCH

Greener and Additive-Free Reactions in Deep Eutectic Solvent: One-Pot, Three-Component Synthesis of Highly Substituted Pyridines

(2017) Najmedin Azizi et al.   ChemistrySelect

Design, synthesis and biological evaluation of benzyloxyphenyl-methylaminophenol derivatives as STAT3 signaling pathway inhibitors

(2016) Dingding Gao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, PM3-Semiempirical, and Biological Evaluation of Pyrazolo[4,3-c]quinolinones

(2016) Wafaa S. Hamama et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

(2016) Beatriz Baragaña et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders

(2015) Maria Gabriella Brasca et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of quinoline-chalcone hybrids as potential antiulcer agents

(2015) Koneni V. Sashidhara et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of the anti-inflammatory activity of quinoline derivatives

(2015) Xiang Wen et al.   MEDICINAL CHEMISTRY RESEARCH

Quinoline: A promising antitubercular target

(2014) Rangappa S. Keri et al.   BIOMEDICINE & PHARMACOTHERAPY

Synthesis and evaluation of 7-chloro-4-(piperazin-1-yl)quinoline-sulfonamide as hybrid antiprotozoal agents

(2013) Attar Salahuddin et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of novel Jak2–Stat pathway inhibitors with extended residence time on target

(2013) Huiping Guan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovering Some Novel 7-Chloroquinolines Carrying a Biologically Active Benzenesulfonamide Moiety as a New Class of Anticancer Agents

(2013) Mohammed Salem Al-Dosari et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Discovery of 1-Methyl-1H-imidazole Derivatives as Potent Jak2 Inhibitors

(2013) Qibin Su et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quinoline: A versatile heterocyclic

(2012) Akranth Marella et al.   SAUDI PHARMACEUTICAL JOURNAL

Synthesis and antiproliferative evaluation of 2,3-diarylquinoline derivatives

(2011) Chih-Hua Tseng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Green synthesis of novel quinoline based imidazole derivatives and evaluation of their antimicrobial activity

(2011) N.C. Desai et al.   Journal of Saudi Chemical Society

Quinolines and structurally related heterocycles as antimalarials

(2010) Kirandeep Kaur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New quinoline derivatives: Synthesis and investigation of antibacterial and antituberculosis properties

(2010) Sumesh Eswaran et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Advances in the Syntheses of Quinoline and Quinoline-Annulated Ring Systems&#

(2008) Sudharshan Madapa et al.   CURRENT ORGANIC CHEMISTRY

Quinol-2-thione compounds as corrosion inhibitors for mild steel in acid solution

(2007) R.A. Prabhu et al.   MATERIALS CHEMISTRY AND PHYSICS