Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation

METTL3 Modulates Osteoclast Differentiation and Function by Controlling RNA Stability and Nuclear Export

(2020) Di Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

N6-methyladenosine demethylase FTO promotes M1 and M2 macrophage activation

(2020) Xiaofei Gu et al.   CELLULAR SIGNALLING

Histone deacetylase inhibitor CI-994 inhibits osteoclastogenesis via suppressing NF-κB and the downstream c-Fos/NFATc1 signaling pathways

(2019) Di Guo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment

(2018) Rongyao Xu et al.   AGING CELL

FTO demethylase activity is essential for normal bone growth and bone mineralization in mice

(2018) Gregor Sachse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Multiple functions of m6A RNA methylation in cancer

(2018) Yutian Pan et al.   Journal of Hematology & Oncology

The GDF11-FTO-PPARγ axis controls the shift of osteoporotic MSC fate to adipocyte and inhibits bone formation during osteoporosis

(2018) Guang-Si Shen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα

(2017) Seyeon Bae et al.   JOURNAL OF CLINICAL INVESTIGATION

Using Mendelian randomization to investigate a possible causal relationship between adiposity and increased bone mineral density at different skeletal sites in children

(2016) John P Kemp et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Suppression of EZH2 Prevents the Shift of Osteoporotic MSC Fate to Adipocyte and Enhances Bone Formation During Osteoporosis

(2016) Huan Jing et al.   MOLECULAR THERAPY

DecreasedN6-Methyladenosine in Peripheral Blood RNA From Diabetic Patients Is Associated WithFTOExpression Rather ThanALKBH5

(2015) Fan Shen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops

(2015) Jing Li et al.   Scientific Reports

FTO Inhibits Insulin Secretion and Promotes NF-κB Activation through Positively Regulating ROS Production in Pancreatic β cells

(2015) Hong-Qi Fan et al.   PLoS One

FTO genotype and aging: pleiotropic longitudinal effects on adiposity, brain function, impulsivity and diet

(2014) Y-F Chuang et al.   MOLECULAR PSYCHIATRY

Functional Impairment of Bone Formation in the Pathogenesis of Osteoporosis: The Bone Marrow Regenerative Competence

(2013) Joseph P. Bidwell et al.   Current Osteoporosis Reports

The Fat Mass and Obesity Associated Gene, FTO, Is Also Associated with Osteoporosis Phenotypes

(2011) Yan Guo et al.   PLoS One

Targeted exercise against osteoporosis: A systematic review and meta-analysis for optimising bone strength throughout life

(2010) Riku Nikander et al.   BMC Medicine

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis

(2010) Vijay K Yadav et al.   NATURE MEDICINE

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly

(2010) A. J. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival

(2008) Anne Gingery et al.   EXPERIMENTAL CELL RESEARCH