A novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthritis via reciprocal regulation of Th17 and Treg cells

IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rβ1 internalization and suppress EAE

(2020) Susanta Mondal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-12 and IL-23—Close Relatives with Structural Homologies but Distinct Immunological Functions

(2020) Doreen M. Floss et al.   Cells

Interleukin-35 in immune-related diseases: protection or destruction

(2019) Junfeng Zhang et al.   IMMUNOLOGY

The Immunobiology of the Interleukin-12 Family: Room for Discovery

(2019) Elia D. Tait Wojno et al.   IMMUNITY

The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man

(2019) Charlie Bridgewood et al.   INFLAMMATION RESEARCH

Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1

(2018) Yehudi Bloch et al.   IMMUNITY

Germinal Center B Cells Are Essential for Collagen-Induced Arthritis

(2018) Albert Dahdah et al.   Arthritis & Rheumatology

Association Between Marginal Jawbone Loss and Onset of Rheumatoid Arthritis and Relationship to Plasma Levels of RANKL

(2018) Elin Kindstedt et al.   Arthritis & Rheumatology

Epstein-Barr virus-induced gene 3 (EBI3) can mediate IL-6trans-signaling

(2017) Salma Chehboun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selected cytokine pathways in rheumatoid arthritis

(2017) Mélissa Noack et al.   Seminars in Immunopathology

The Fos-Related Antigen 1–JUNB/Activator Protein 1 Transcription Complex, a Downstream Target of Signal Transducer and Activator of Transcription 3, Induces T Helper 17 Differentiation and Promotes Experimental Autoimmune Arthritis

(2017) Young-Mee Moon et al.   Frontiers in Immunology

IL-27-Induced Type 1 Regulatory T-Cells Produce Oxysterols that Constrain IL-10 Production

(2017) Solenne Vigne et al.   Frontiers in Immunology

Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis

(2016) Ursula Fearon et al.   Nature Reviews Rheumatology

Correlation between circulating VEGF levels and disease activity in rheumatoid arthritis: a meta-analysis

(2016) Young Ho Lee et al.   ZEITSCHRIFT FUR RHEUMATOLOGIE

Association between polymorphisms of interleukin 12 and rheumatoid arthritis associated biomarkers in a Chinese population

(2015) Li Shen et al.   CYTOKINE

IL-12p40 Homodimer Ameliorates Experimental Autoimmune Arthritis

(2015) Seon-Yeong Lee et al.   JOURNAL OF IMMUNOLOGY

Dysregulated Serum IL-23 and SIRT1 Activity in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis

(2015) Daniel Wendling et al.   PLoS One

Interleukin-6 and its receptors: A highly regulated and dynamic system

(2014) Janina Wolf et al.   CYTOKINE

Non-Canonical Interleukin 23 Receptor Complex Assembly

(2014) Jutta Schröder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin-35 induces regulatory B cells that suppress autoimmune disease

(2014) Ren-Xi Wang et al.   NATURE MEDICINE

Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity

(2013) M E Doorenspleet et al.   ANNALS OF THE RHEUMATIC DISEASES

The composition and signaling of the IL-35 receptor are unconventional

(2012) Lauren W Collison et al.   NATURE IMMUNOLOGY

IL-12 family cytokines: immunological playmakers

(2012) Dario A A Vignali et al.   NATURE IMMUNOLOGY

gp130 at the nexus of inflammation, autoimmunity, and cancer

(2010) J. S. Silver et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

(2009) C. Diveu et al.   JOURNAL OF IMMUNOLOGY

STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25− effector T cells

(2008) Laura Passerini et al.   INTERNATIONAL IMMUNOLOGY