Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells

A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis

(2021) Lisa K. McLellan et al.   PLoS Pathogens

Targeting desmosomal adhesion and signalling for intestinal barrier stabilization in inflammatory bowel diseases—Lessons from experimental models and patients

(2020) Nicolas Schlegel et al.   Acta Physiologica

Scaling up single-cell mechanics to multicellular tissues – the role of the intermediate filament–desmosome network

(2020) Joshua A. Broussard et al.   JOURNAL OF CELL SCIENCE

A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding

(2020) Sabine Bernegger et al.   Scientific Reports

Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations

(2019) Anna Zawilak-Pawlik et al.   Scientific Reports

Extracellular HtrA serine proteases: An emerging new strategy in bacterial pathogenesis

(2018) Steffen Backert et al.   CELLULAR MICROBIOLOGY

Gastric cancer: epidemiology, prevention, and therapy

(2018) Marino Venerito et al.   HELICOBACTER

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Staphylococcus aureus Induces Increased Serine Protease Activity in Keratinocytes

(2017) Michael R. Williams et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Proteolysis in Helicobacter pylori-Induced Gastric Cancer

(2017) Gernot Posselt et al.   Toxins

Tight junctions: from simple barriers to multifunctional molecular gates

(2016) Ceniz Zihni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Calcium binding protects E-cadherin from cleavage by Helicobacter pylori HtrA

(2016) Thomas P. Schmidt et al.   Gut Pathogens

Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA

(2016) Thomas P. Schmidt et al.   Scientific Reports

Epithelial cell ADAM17 activation by Helicobacter pylori: role of ADAM17 C-terminus and Threonine-735 phosphorylation

(2015) Urszula L. McClurg et al.   MICROBES AND INFECTION

Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells

(2015) Barbara Sobotič et al.   MOLECULAR & CELLULAR PROTEOMICS

Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier

(2015) Ryuta Kamekura et al.   MOLECULAR BIOLOGY OF THE CELL

The stability and activity of recombinantHelicobacter pyloriHtrA under stress conditions

(2012) Benjamin Hoy et al.   JOURNAL OF BASIC MICROBIOLOGY

Desmoglein as a Target in Skin Disease and Beyond

(2011) Masayuki Amagai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Tissue Organization by Cadherin Adhesion Molecules: Dynamic Molecular and Cellular Mechanisms of Morphogenetic Regulation

(2011) Carien M. Niessen et al.   PHYSIOLOGICAL REVIEWS

Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

(2010) Benjamin Hoy et al.   EMBO REPORTS

Gastric Cancer: An Infectious Disease

(2010) M. Blanca Piazuelo et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics

(2010) Pearl P.Y. Lie et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14

(2010) Hongjie Wang et al.   NATURE MEDICINE

Diverse evolutionary paths to cell adhesion

(2010) Monika Abedin et al.   TRENDS IN CELL BIOLOGY

Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pylori infection

(2009) Wiebke Schirrmeister et al.   EXPERIMENTAL CELL RESEARCH

The desmosome and pemphigus

(2008) Jens Waschke   HISTOCHEMISTRY AND CELL BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Prediction of Extracellular Proteases of the Human Pathogen Helicobacter pylori Reveals Proteolytic Activity of the Hp1018/19 Protein HtrA

(2008) Martin Löwer et al.   PLoS One

Desmosome structure, composition and function

(2007) David Garrod et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES