A selective antibiotic for Lyme disease

Long-haul COVID: heed the lessons from other infection-triggered illnesses

(2021) John N Aucott et al.   LANCET

An Antibiotic-Impacted Microbiota Compromises the Development of Colonic Regulatory T Cells and Predisposes to Dysregulated Immune Responses

(2021) Xiaozhou Zhang et al.   mBio

Structural and biomolecular analyses of Borrelia burgdorferi BmpD reveal a substrate-binding protein of an ABC-type nucleoside transporter family.

(2020) Julia Cuellar et al.   INFECTION AND IMMUNITY

The Science of Antibiotic Discovery

(2020) Kim Lewis   CELL

In Vitro Susceptibility of Treponema pallidum subsp. pallidum to Doxycycline

(2020) Diane G. Edmondson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Antimicrobials from Uncultured Bacteria Acting against Mycobacterium tuberculosis

(2020) Jeffrey Quigley et al.   mBio

A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients

(2020) Madeleine Morrissette et al.   mBio

The neuroactive potential of the human gut microbiota in quality of life and depression

(2019) Mireia Valles-Colomer et al.   Nature Microbiology

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

A new antibiotic selectively kills Gram-negative pathogens

(2019) Yu Imai et al.   NATURE

Antimicrobial resistance in sexually transmitted infections

(2019) Vivian Tien et al.   JOURNAL OF TRAVEL MEDICINE

The gut microbiome and elevated cardiovascular risk in obesity and autoimmunity

(2018) Lora J. Kasselman et al.   ATHEROSCLEROSIS

Transmission of the relapsing fever spirochete, Borrelia miyamotoi , by single transovarially-infected larval Ixodes scapularis ticks

(2018) Nicole E. Breuner et al.   Ticks and Tick-Borne Diseases

Long-Term In Vitro Culture of the Syphilis Spirochete Treponema pallidum subsp. pallidum

(2018) Diane G. Edmondson et al.   mBio

Identifying vancomycin as an effective antibiotic for killing Borrelia burgdorferi

(2018) Xiaoqian Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Qiita: rapid, web-enabled microbiome meta-analysis

(2018) Antonio Gonzalez et al.   NATURE METHODS

Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [11C]DPA-713 PET

(2018) Jennifer M. Coughlin et al.   Journal of Neuroinflammation

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

(2018) Tommi Vatanen et al.   NATURE

Predicting the ligand-binding properties of Borrelia burgdorferi s.s. Bmp proteins in light of the conserved features of related Borrelia proteins

(2018) Mia Åstrand et al.   JOURNAL OF THEORETICAL BIOLOGY

Breaking the permeability barrier ofEscherichia coliby controlled hyperporination of the outer membrane.

(2016) Ganesh Krishnamoorthy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

CCL19 as a Chemokine Risk Factor for Posttreatment Lyme Disease Syndrome: a Prospective Clinical Cohort Study

(2016) John N. Aucott et al.   Clinical and Vaccine Immunology

Lyme borreliosis

(2016) Allen C. Steere et al.   Nature Reviews Disease Primers

Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells

(2015) Bijaya Sharma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cyclic di-GMP Modulates Gene Expression in Lyme Disease Spirochetes at the Tick-Mammal Interface To Promote Spirochete Survival during the Blood Meal and Tick-to-Mammal Transmission

(2015) Melissa J. Caimano et al.   INFECTION AND IMMUNITY

Posttreatment Lyme Disease Syndrome

(2015) John N. Aucott   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A

(2015) Yury S. Polikanov et al.   MOLECULAR CELL

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

Targeting DnaN for tuberculosis therapy using novel griselimycins

(2015) A. Kling et al.   SCIENCE

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

(2015) Kymberleigh A. Romano et al.   mBio

Health Care Costs, Utilization and Patterns of Care following Lyme Disease

(2015) Emily R. Adrion et al.   PLoS One

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

(2014) Ekaterina Gavrish et al.   CHEMISTRY & BIOLOGY

Antibiotics and the gut microbiota

(2014) Sheetal R. Modi et al.   JOURNAL OF CLINICAL INVESTIGATION

Stage-specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation

(2014) Radha Iyer et al.   MOLECULAR MICROBIOLOGY

Impact of biodiversity and seasonality on Lyme-pathogen transmission

(2014) Yijun Lou et al.   Theoretical Biology and Medical Modelling

Strain-Specific Variation of the Decorin-Binding Adhesin DbpA Influences the Tissue Tropism of the Lyme Disease Spirochete

(2014) Yi-Pin Lin et al.   PLoS Pathogens

High-Level Pacidamycin Resistance in Pseudomonas aeruginosa Is Mediated by an Opp Oligopeptide Permease Encoded by theopp-fabIOperon

(2013) Anita Mistry et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Elevated Levels of IL-23 in a Subset of Patients With Post-Lyme Disease Symptoms Following Erythema Migrans

(2013) K. Strle et al.   CLINICAL INFECTIOUS DISEASES

Development of a foundation for a case definition of post-treatment Lyme disease syndrome

(2013) John N. Aucott et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan

(2013) A. K. Martinez et al.   NUCLEIC ACIDS RESEARCH

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition

(2013) Cédric Orelle et al.   NUCLEIC ACIDS RESEARCH

Treatment of Erythema Migrans With Doxycycline for 10 Days Versus 15 Days

(2012) D. Stupica et al.   CLINICAL INFECTIOUS DISEASES

Rrp2, a Prokaryotic Enhancer-Like Binding Protein, Is Essential for Viability of Borrelia burgdorferi

(2012) A. M. Groshong et al.   JOURNAL OF BACTERIOLOGY

Chiral Pool Based Efficient Synthesis of the Aminocyclitol Core and Furanoside of (−)- Hygromycin A: Formal Total Synthesis of (−)-Hygromycin A

(2012) Hong-Jay Lo et al.   ORGANIC LETTERS

Elimination of Borrelia burgdorferi and Anaplasma phagocytophilum in Rodent Reservoirs and Ixodes scapularis Ticks Using a Doxycycline Hyclate-Laden Bait

(2011) Marc C. Dolan et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

The Natural Product Cyclomarin Kills Mycobacterium Tuberculosis by Targeting the ClpC1 Subunit of the Caseinolytic Protease

(2011) Esther K. Schmitt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

(2011) Daniel McDonald et al.   ISME Journal

Multiplex PCR as a tool for validating plasmid content of Borrelia burgdorferi

(2011) Ignas Bunikis et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Shifting the balance: antibiotic effects on host–microbiota mutualism

(2011) Benjamin P. Willing et al.   NATURE REVIEWS MICROBIOLOGY

Brain?Gut?Microbe Communication in Health and Disease

(2011) Sue Grenham et al.   Frontiers in Physiology

Comparative Efficacies of Human Simulated Exposures of Telavancin and Vancomycin against Methicillin-Resistant Staphylococcus aureus with a Range of Vancomycin MICs in a Murine Pneumonia Model

(2010) J. L. Crandon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

(2010) J. G. Caporaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of a Single-Plasmid-Based Regulatable Gene Expression System for Borrelia burgdorferi

(2009) C. R. Whetstine et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Chronic Lyme Disease: A Review

(2008) Adriana Marques   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Molecular Mechanism of Drug-Dependent Ribosome Stalling

(2008) Nora Vazquez-Laslop et al.   MOLECULAR CELL