Magnesium sensing via LFA-1 regulates CD8+ T cell effector function

Triggered Drug Release From Liposomes: Exploiting the Outer and Inner Tumor Environment

(2021) Marina Santiago Franco et al.   Frontiers in Oncology

SAKK 16/14: Durvalumab in Addition to Neoadjuvant Chemotherapy in Patients With Stage IIIA(N2) Non–Small-Cell Lung Cancer—A Multicenter Single-Arm Phase II Trial

(2021) Sacha I. Rothschild et al.   JOURNAL OF CLINICAL ONCOLOGY

LFA-1 in T cell priming, differentiation, and effector functions

(2021) Audrey Gérard et al.   TRENDS IN IMMUNOLOGY

Rapid Undetectable MRD (uMRD) Responses in Patients with Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Treated with Lisocabtagene Maraleucel (liso-cel), a CD19-Directed CAR T Cell Product: Updated Results from Transcend CLL 004, a Phase 1/2 Study Including Patients with High-Risk Disease Previously Treated with Ibrutinib

(2020) Tanya Siddiqi et al.   BLOOD

Phase 1b/2 study of blinatumomab in Japanese adults with relapsed/refractory acute lymphoblastic leukemia

(2020) Hitoshi Kiyoi et al.   CANCER SCIENCE

Dietary modifications for enhanced cancer therapy

(2020) Naama Kanarek et al.   NATURE

Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study

(2020) Jeremy S Abramson et al.   LANCET

Magnesium levels and outcome after allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia

(2020) Linus Angenendt et al.   ANNALS OF HEMATOLOGY

Sensing between reactions – how the metabolic microenvironment shapes immunity

(2019) J. Lötscher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Hypomagnesemia and Survival in Patients with Ovarian Cancer Who Received Chemotherapy with Carboplatin

(2019) Wenli Liu et al.   ONCOLOGIST

Mg2+ regulation of kinase signaling and immune function

(2019) Chryssa Kanellopoulou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Plasma magnesium is inversely associated with Epstein-Barr virus load in peripheral blood and Burkitt lymphoma in Uganda

(2018) Ravell Juan et al.   Cancer Epidemiology

Ligand- and cation-induced structural alterations of the leukocyte integrin LFA-1

(2018) Mehmet Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy

(2018) Travis I. Moore et al.   Cell Reports

NY-ESO-1 Based Immunotherapy of Cancer: Current Perspectives

(2018) Remy Thomas et al.   Frontiers in Immunology

Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial

(2018) Frederick L Locke et al.   LANCET ONCOLOGY

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

(2017) Sattva S. Neelapu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells

(2017) Michel Enamorado et al.   Nature Communications

Label-free Analysis of CD8 + T Cell Subset Proteomes Supports a Progressive Differentiation Model of Human-Virus-Specific T Cells

(2017) Michiel C. van Aalderen et al.   Cell Reports

Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

(2016) Yuko Nakamura et al.   BIOCONJUGATE CHEMISTRY

Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis

(2016) Zhichao Fan et al.   Nature Communications

InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

(2015) Henry Heberle et al.   BMC BIOINFORMATICS

Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study

(2015) Max S Topp et al.   LANCET ONCOLOGY

Association Between Serum Magnesium and Anemia: China Health and Nutrition Survey

(2014) Yiqiang Zhan et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

T Cells Bearing a Chimeric Antigen Receptor against Prostate-Specific Membrane Antigen Mediate Vascular Disruption and Result in Tumor Regression

(2014) S. P. Santoro et al.   Cancer Immunology Research

Hypomagnesemia is a significant predictor of cardiovascular and non-cardiovascular mortality in patients undergoing hemodialysis

(2013) Yusuke Sakaguchi et al.   KIDNEY INTERNATIONAL

Molecular Insights for Optimizing T Cell Receptor Specificity Against Cancer

(2013) Michael Hebeisen et al.   Frontiers in Immunology

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

(2012) C. Lee et al.   Science Translational Medicine

Integrins as therapeutic targets

(2012) Simon L. Goodman et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The regulation of integrin function by divalent cations

(2012) Kun Zhang et al.   Cell Adhesion & Migration

Dietary magnesium intake and risk of stroke: a meta-analysis of prospective studies

(2011) Susanna C Larsson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Regulation of integrin affinity on cell surfaces

(2011) Thomas Schürpf et al.   EMBO JOURNAL

Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function

(2010) D. A. Schmid et al.   JOURNAL OF IMMUNOLOGY

Magnesium Supplementation and Osteoporosis

(2010) J. E. Sojka   NUTRITION REVIEWS

LFA-1 Affinity Regulation Is Necessary for the Activation and Proliferation of Naive T Cells

(2009) Yang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LFA-1 Regulates CD8+T Cell Activation via T Cell Receptor-mediated and LFA-1-mediated Erk1/2 Signal Pathways

(2009) Dan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Synaptic Basis for Paracrine Interleukin-2 Signaling during Homotypic T Cell Interaction

(2008) Catherine A. Sabatos et al.   IMMUNITY

Distinct Roles of β1 Metal Ion-dependent Adhesion Site (MIDAS), Adjacent to MIDAS (ADMIDAS), and Ligand-associated Metal-binding Site (LIMBS) Cation-binding Sites in Ligand Recognition by Integrin α2β1

(2008) Dimitra Valdramidou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Daily Magnesium Intake and Serum Magnesium Concentration among Japanese People

(2008) Yoriko Akizawa et al.   JOURNAL OF EPIDEMIOLOGY