The molecular makeup of peripheral and central baroreceptors: stretching a role for Transient Receptor Potential (TRP), Epithelial Sodium Channel (ENaC), Acid Sensing Ion Channel (ASIC), and Piezo channels

Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Patients With Heart Failure Supported With Continuous-Flow Left Ventricular Assist Devices

(2021) Christine Sailer et al.   Circulation-Heart Failure

Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

(2021) Jordan W. Squair et al.   NATURE

Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis

(2020) Andras Garami et al.   PHARMACOLOGY & THERAPEUTICS

Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow

(2020) Nephtali Marina et al.   Nature Communications

Transient receptor potential canonical 5 channel is involved in the cardiac damage related to obstructive sleep apnea-hypopnea syndrome in rats

(2020) Wen Wen et al.   Annals of Palliative Medicine

TRPV1 genetic polymorphisms and risk of COPD or COPD combined with PH in the Han Chinese population

(2020) Mingmei Xiong et al.   CELL CYCLE

Solving Baroreceptor Mystery: Role of PIEZO Ion Channels

(2019) Suzanne D. Burke et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Missing Pieces of the Piezo1/Piezo2 Baroreceptor Hypothesis: An Autonomic Perspective

(2019) Sean D. Stocker et al.   JOURNAL OF NEUROPHYSIOLOGY

Force Sensing by Piezo Channels in Cardiovascular Health and Disease

(2019) David J. Beech et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Piezo1 regulates calcium oscillations and cytokine release from astrocytes

(2019) María Velasco‐Estevez et al.   GLIA

Hereditary xerocytosis - spectrum and clinical manifestations of variants in the PIEZO1 gene, including co-occurrence with a novel β-globin mutation

(2019) Karolina Maciak et al.   BLOOD CELLS MOLECULES AND DISEASES

Differential effect of angiotensin II and blood pressure on hippocampal inflammation in mice

(2018) M. Florencia Iulita et al.   Journal of Neuroinflammation

Blood-brain barrier dysfunction and recovery after ischemic stroke

(2018) Xiaoyan Jiang et al.   PROGRESS IN NEUROBIOLOGY

Author Correction: TRPC5 channels participate in pressure-sensing in aortic baroreceptors

(2018) On-Chai Lau et al.   Nature Communications

TRPV1 and BDKRB2 receptor polymorphisms can influence the exercise pressor reflex

(2018) Karambir Notay et al.   JOURNAL OF PHYSIOLOGY-LONDON

Baroreflex functionality in the eye of diffusion tensor imaging

(2018) Ching-Yi Tsai et al.   JOURNAL OF PHYSIOLOGY-LONDON

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

(2018) Wei-Zheng Zeng et al.   SCIENCE

SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling

(2017) Jesse A. Stokum et al.   GLIA

Responses of Nucleus Tractus Solitarius (NTS) early and late neurons to blood pressure changes in anesthetized F344 rats

(2017) Jenya Kolpakova et al.   PLoS One

Endogenous Hydrogen Sulfide Enhances Carotid Sinus Baroreceptor Sensitivity by Activating the Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) Channel

(2017) Wen Yu et al.   Journal of the American Heart Association

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Physiological significance of TRPV2 as a mechanosensor, thermosensor and lipid sensor

(2016) Koji Shibasaki   Journal of Physiological Sciences

TRPC5 channels participate in pressure-sensing in aortic baroreceptors

(2016) On-Chai Lau et al.   Nature Communications

Altered ENaC Is Associated With Aortic Baroreceptor Dysfunction in Chronic Heart Failure

(2015) Yu-Long Li et al.   AMERICAN JOURNAL OF HYPERTENSION

The speed of swelling kinetics modulates cell volume regulation and calcium signaling in astrocytes: A different point of view on the role of aquaporins

(2015) Maria Grazia Mola et al.   GLIA

Molecular pathophysiology of cerebral edema

(2015) Jesse A Stokum et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Muller Glia

(2015) A. O. Jo et al.   JOURNAL OF NEUROSCIENCE

Architecture of the mammalian mechanosensitive Piezo1 channel

(2015) Jingpeng Ge et al.   NATURE

ASICs and cardiovascular homeostasis

(2015) François M. Abboud et al.   NEUROPHARMACOLOGY

Magnesium in Man: Implications for Health and Disease

(2015) Jeroen H. F. de Baaij et al.   PHYSIOLOGICAL REVIEWS

Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis

(2015) Elisavet Fotiou et al.   Nature Communications

Piezo1 ion channel pore properties are dictated by C-terminal region

(2015) Bertrand Coste et al.   Nature Communications

Association of SCNN1A Single Nucleotide Polymorphisms with neonatal respiratory distress syndrome

(2015) Wang Li et al.   Scientific Reports

Plasma Membrane Mechanical Stress Activates TRPC5 Channels

(2015) Bing Shen et al.   PLoS One

Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5

(2014) Margaret J. McMillin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1

(2014) Yasunori Takayama et al.   FASEB JOURNAL

Mechanism of Brain Tumor Headache

(2014) Lynne P. Taylor   HEADACHE

TRPM4 Channels Couple Purinergic Receptor Mechanoactivation and Myogenic Tone Development in Cerebral Parenchymal Arterioles

(2014) Yao Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Astrocytes express functional TRPV2 ion channels

(2013) Koji Shibasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acid-sensing ion channels (ASICs): therapeutic targets for neurological diseases and their regulation

(2013) Hae-Jin Kweon et al.   BMB Reports

ENaC γ-expressing astrocytes in the circumventricular organs, white matter, and ventral medullary surface: Sites for Na+ regulation by glial cells

(2013) Rebecca L. Miller et al.   JOURNAL OF CHEMICAL NEUROANATOMY

TRPM4 channels in smooth muscle function

(2013) Scott Earley   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Physiology and Redundancy

(2013) Michael J. Joyner   PHYSIOLOGY

The biochemistry and function of pannexin channels

(2012) Silvia Penuela et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Sympathetic Neural and Hemodynamic Responses to Upright Tilt in Patients With Pulsatile and Nonpulsatile Left Ventricular Assist Devices

(2012) David W. Markham et al.   Circulation-Heart Failure

Vasopressin Secretion Control: Central Neural Pathways, Neurotransmitters and Effects of Drugs

(2012) Michele Iovino et al.   CURRENT PHARMACEUTICAL DESIGN

Rapid Aquaporin Translocation Regulates Cellular Water Flow

(2012) Matthew T. Conner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

TRPV1 is important for mechanical and heat sensitivity in uninjured animals and development of heat hypersensitivity after muscle inflammation

(2012) Roxanne Y. Walder et al.   PAIN

Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca2+ events, and IKCa channels, reducing arteriolar tone

(2012) P. Bagher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Baroreflex sensitivity: mechanisms and measurement

(2012) C. A. Swenne   Netherlands Heart Journal

An investigation of the safety and pharmacokinetics of the novel TRPV1 antagonist XEN-D0501 in healthy subjects

(2011) Patrick Round et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Functional interaction between AQP2 and TRPV4 in renal cells

(2011) Luciano Galizia et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Expression Pattern of TRPV1 in Brain

(2011) A. Menigoz et al.   JOURNAL OF NEUROSCIENCE

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

(2011) Eiji Shigetomi et al.   NATURE NEUROSCIENCE

Calcium-dependent decrease in the single-channel conductance of TRPV1

(2011) Damien S. K. Samways et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes

(2011) V. Benfenati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological inhibition of TRPM4 hyperpolarizes vascular smooth muscle

(2010) Albert L. Gonzales et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Existence and distinction of acid-evoked currents in rat astrocytes

(2010) Chao Huang et al.   GLIA

TRP channels of intracellular membranes

(2010) Xian-Ping Dong et al.   JOURNAL OF NEUROCHEMISTRY

Genetic Variations in the Sodium Balance-Regulating Genes ENaC, NEDD4L, NDFIP2 and USP2 Influence Blood Pressure and Hypertension

(2010) Hyun-Seok Jin et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema

(2010) A. S. Thrane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Polycystins under Pressure

(2009) Bernd Nilius   CELL

Polycystin-1 and -2 Dosage Regulates Pressure Sensing

(2009) Reza Sharif-Naeini et al.   CELL

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Expression of transient receptor potential ankyrin 1 (TRPA1) in the rat trigeminal sensory afferents and spinal dorsal horn

(2009) Yun Sook Kim et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Pannexin 1: The Molecular Substrate of Astrocyte "Hemichannels"

(2009) R. Iglesias et al.   JOURNAL OF NEUROSCIENCE

TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons

(2009) K. Y. Kwan et al.   JOURNAL OF NEUROSCIENCE

Sensing of Blood Pressure Increase by Transient Receptor Potential Vanilloid 1 Receptors on Baroreceptors

(2009) H. Sun et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation

(2009) Yongjun Lu et al.   NEURON

Impaired pressure-induced constriction in mouse middle cerebral arteries of ASIC2 knockout mice

(2008) Kimberly P. Gannon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Gap Junctions in the Control of Vascular Function

(2008) Xavier F. Figueroa et al.   ANTIOXIDANTS & REDOX SIGNALING

Impaired baroreflex sensitivity predicts outcome of acute intracerebral hemorrhage

(2008) Marek Sykora et al.   CRITICAL CARE MEDICINE

Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation

(2008) Daniel Becker et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Sensing Tension

(2008) Heather A. Drummond et al.   HYPERTENSION

Extracellular Protons Regulate Human ENaC by Modulating Na+Self-inhibition

(2008) Daniel M. Collier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IP3Receptor Binds to and Sensitizes TRPV4 Channel to Osmotic Stimuli via a Calmodulin-binding Site

(2008) Anna Garcia-Elias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic variation in the ASIC3 gene influences blood pressure levels in Taiwanese

(2008) Yu-Lin Ko et al.   JOURNAL OF HYPERTENSION

The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal horn

(2008) Hong-Yi Zhou et al.   JOURNAL OF NEUROCHEMISTRY

Hypoosmotic- and pressure-induced membrane stretch activate TRPC5 channels

(2008) Ana Gomis et al.   JOURNAL OF PHYSIOLOGY-LONDON

The arterial baroreflex: Functional organization and involvement in neurologic disease

(2008) E. E. Benarroch   NEUROLOGY

ASIC proteins regulate smooth muscle cell migration

(2007) Samira C. Grifoni et al.   MICROVASCULAR RESEARCH