Remdesivir induces persistent mitochondrial and structural damage in human induced pluripotent stem cell-derived cardiomyocytes
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Remdesivir induces persistent mitochondrial and structural damage in human induced pluripotent stem cell-derived cardiomyocytes
Authors
Keywords
-
Journal
CARDIOVASCULAR RESEARCH
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2021-10-01
DOI
10.1093/cvr/cvab311
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Serious bradycardia and remdesivir for coronavirus 2019 (COVID-19): a new safety concerns
- (2021) Anthony Touafchia et al. CLINICAL MICROBIOLOGY AND INFECTION
- Potential remdesivir‐related transient bradycardia in patients with coronavirus disease 2019 (COVID‐19)
- (2021) Carlo Pallotto et al. JOURNAL OF MEDICAL VIROLOGY
- Cell surface markers for immunophenotyping human pluripotent stem cell-derived cardiomyocytes
- (2021) Kenneth R. Boheler et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
- (2020) Manli Wang et al. CELL RESEARCH
- Autopsy Findings and Venous Thromboembolism in Patients With COVID-19
- (2020) Dominic Wichmann et al. ANNALS OF INTERNAL MEDICINE
- The cell surface marker CD36 selectively identifies matured, mitochondria-rich hPSC-cardiomyocytes
- (2020) Ellen Ngar-Yun Poon et al. CELL RESEARCH
- Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
- (2020) Yeming Wang et al. LANCET
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Remdesivir for 5 or 10 Days in Patients with Severe Covid-19
- (2020) Jason D. Goldman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Remdesivir for the Treatment of Covid-19 — Preliminary Report
- (2020) John H. Beigel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Remdesivir: Review of pharmacology, pre‐clinical data and emerging clinical experience for COVID‐19
- (2020) Sarah CJ Jorgensen et al. PHARMACOTHERAPY
- Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
- (2020) Wanchao Yin et al. SCIENCE
- Potential Effects of Coronaviruses on the Cardiovascular System
- (2020) Mohammad Madjid et al. JAMA Cardiology
- Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China
- (2020) Shaobo Shi et al. JAMA Cardiology
- Why COVID-19 Silent Hypoxemia Is Baffling to Physicians
- (2020) Martin J. Tobin et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
- (2020) Liuliu Yang et al. Cell Stem Cell
- Direct SARS-CoV-2 infection of the heart potentiates the cardiovascular sequelae of COVID-19
- (2020) Rajendran J.C. Bose et al. DRUG DISCOVERY TODAY
- The association between cardiac injury and outcomes in hospitalized patients with COVID-19
- (2020) Shahrokh Karbalai Saleh et al. Internal and Emergency Medicine
- Association Between Hypoxemia and Mortality in Patients With COVID-19
- (2020) Jiang Xie et al. MAYO CLINIC PROCEEDINGS
- Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2
- (2020) Brandi N. Williamson et al. NATURE
- Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice
- (2020) Andrea J. Pruijssers et al. Cell Reports
- Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19)
- (2020) Valentina O. Puntmann et al. JAMA Cardiology
- Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes
- (2020) Seong Woo Choi et al. ANTIVIRAL RESEARCH
- SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes
- (2020) Denisa Bojkova et al. CARDIOVASCULAR RESEARCH
- Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Platform to Study SARS-CoV-2 Related Myocardial Injury
- (2020) Chun-Ka Wong et al. CIRCULATION JOURNAL
- Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19
- (2020) Christoph D. Spinner et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Immune Mechanisms in Cardiovascular Diseases Associated With Viral Infection
- (2020) Radha Gopal et al. Frontiers in Immunology
- Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing
- (2020) Sawittree Sahakijpijarn et al. Pharmaceutics
- Off-Target In Vitro Profiling Demonstrates that Remdesivir Is a Highly Selective Antiviral Agent
- (2020) Yili Xu et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Cardiovascular Manifestations of COVID-19 Infection
- (2020) Ajit Magadum et al. Cells
- Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir
- (2019) Egor Tchesnokov et al. Viruses-Basel
- Use of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes in Preclinical Cancer Drug Cardiotoxicity Testing: A Scientific Statement From the American Heart Association
- (2019) Gary Gintant et al. CIRCULATION RESEARCH
- Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells
- (2019) Xiulan Yang et al. Stem Cell Reports
- Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury
- (2019) Danchen Wu et al. FASEB JOURNAL
- Patient and Disease–Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics
- (2019) David T. Paik et al. PHARMACOLOGICAL REVIEWS
- Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems
- (2018) Tarek Magdy et al. Annual Review of Pharmacology and Toxicology
- Integrated transcriptomic and regulatory network analyses identify microRNA-200c as a novel repressor of human pluripotent stem cell-derived cardiomyocyte differentiation and maturation
- (2018) Ellen Ngar-yun Poon et al. CARDIOVASCULAR RESEARCH
- Differential temporal inhibition of mitochondrial fission by Mdivi-1 exerts effective cardioprotection in cardiac ischemia/reperfusion injury
- (2018) Chayodom Maneechote et al. CLINICAL SCIENCE
- Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
- (2017) Timothy P. Sheahan et al. Science Translational Medicine
- Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes
- (2016) Natalie Weber et al. BASIC RESEARCH IN CARDIOLOGY
- Nanoparticle‐Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia‐Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myocardial Infarction
- (2016) Ayako Ishikita et al. Journal of the American Heart Association
- Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus
- (2015) Joy Y. Feng et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Proteomic Analysis of Human Pluripotent Stem Cell–Derived, Fetal, and Adult Ventricular Cardiomyocytes Reveals Pathways Crucial for Cardiac Metabolism and MaturationCLINICAL PERSPECTIVE
- (2015) Ellen Poon et al. Circulation-Cardiovascular Genetics
- Cardiac dysfunction associated with a nucleotide polymerase inhibitor for treatment of hepatitis C
- (2015) Tariq Ahmad et al. HEPATOLOGY
- Proteomic Analysis of Human Pluripotent Stem Cell–Derived, Fetal, and Adult Ventricular Cardiomyocytes Reveals Pathways Crucial for Cardiac Metabolism and MaturationCLINICAL PERSPECTIVE
- (2015) Ellen Poon et al. Circulation-Cardiovascular Genetics
- Mitochondrial dynamics and mitochondrial quality control
- (2015) Hong-Min Ni et al. Redox Biology
- Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases
- (2013) Stephen L. Archer NEW ENGLAND JOURNAL OF MEDICINE
- Transcriptome-Guided Functional Analyses Reveal Novel Biological Properties and Regulatory Hierarchy of Human Embryonic Stem Cell-Derived Ventricular Cardiomyocytes Crucial for Maturation
- (2013) Ellen Poon et al. PLoS One
- Attenuation of Doxorubicin-Induced Cardiotoxicity by mdivi-1: A Mitochondrial Division/Mitophagy Inhibitor
- (2013) Mayel Gharanei et al. PLoS One
- Mitochondrial division/mitophagy inhibitor (Mdivi) Ameliorates Pressure Overload Induced Heart Failure
- (2012) Srikanth Givvimani et al. PLoS One
- Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition
- (2011) Nadezda Apostolova et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
- (2008) Ann Cassidy-Stone et al. DEVELOPMENTAL CELL
- Adenosine 3′,5′-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors
- (2007) Kaleb C. Lund et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now