Article
Biochemistry & Molecular Biology
Xiaoyan Song, Yuge Zhai, Xin Di, Quanzhi Zhao
Summary: This study investigated the lipid digestion of starch-based Pickering emulsions stabilized by starch particles with different oil phases. The results showed that coconut oil had the highest rate of lipid digestion, while increasing starch concentration had positive effects on lipid digestion and increasing oil fraction had negative impacts. Starch-based Pickering emulsion exhibited super stability against oral and gastric digestion, making it a superior delivery system for lipophilic active substances.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Xiaolong Hu, Yuting Wei, Tianxiang Zhang, Xiaoguo Wang, Yongtao Xu, Weiwei Zhang, Yunlin Zheng
Summary: This study investigated the gut microbiome of sika deer by sampling feces or specific segments of the gastrointestinal tract. The results showed variations in microbial composition and SCFAs among different gastrointestinal sites, suggesting the significant influence of physiological characteristics on the microbial composition.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Chemistry, Applied
Jie Yang, Zhengbiao Gu, Li Cheng, Zhaofeng Li, Caiming Li, Xiaofeng Ban, Yan Hong
Summary: This study developed stable double emulsions as carrier materials using gelatinized starch, with O/W/O double emulsions stabilized by 7 wt% native corn starch showing smaller mean droplet size and excellent storage stability compared to O/W/W and O/W/O double emulsions prepared with highamylose starch.
CARBOHYDRATE POLYMERS
(2021)
Review
Food Science & Technology
Cheng Li, Yiming Hu
Summary: The current definitions of resistant starch (RS) types are mainly based on their interactions with human digestive enzymes in the upper gastrointestinal tract, and do not adequately consider their effects on gut microbiota. This review highlights the limitations of the current definitions and proposes new definitions of RS types from the perspective of gut microbiota, taking into account fermentation rate, fermentation end products, specificity towards gut microbiota, and shifts in gut microbiota caused by RS consumption.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Maroula G. Kokotou, Christiana Mantzourani, Charikleia S. Batsika, Olga G. Mountanea, Ioanna Eleftheriadou, Ourania Kosta, Nikolaos Tentolouris, George Kokotos
Summary: This study presents a fast and straightforward liquid chromatography-high resolution mass spectrometry method for the simultaneous determination of 74 free fatty acids (FFAs) in human plasma. The method avoids derivatization steps and tedious sample preparation, making it suitable for the diagnosis and monitoring of metabolic disorders.
Article
Food Science & Technology
Reza Atraki, Maryam Azizkhani
Summary: The encapsulation of probiotic bacteria within nanofiber mats of CS/SA significantly enhances their survival rate in simulated gastrointestinal conditions, providing a protective effect against exposure to gastric and intestinal fluids.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2021)
Article
Food Science & Technology
Christiana Mantzourani, Charikleia S. Batsika, Maroula G. Kokotou, George Kokotos
Summary: A new method was developed to simultaneously determine multiple fatty acids in yogurt samples, including both common and uncommon ones. The concentrations of various fatty acids in the samples allowed the discrimination between cow and sheep yogurt.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Agricultural Engineering
Manupati Hemalatha, S. Venkata Mohan
Summary: This study investigated the potential of Duckweed in treating dairy wastewater and its utilization as nutritional biomass. The results showed that Duckweed had good treatment efficiency in removing organic carbon, nitrates, and phosphates from wastewater. It also exhibited potential as a nutritional supplement for livestock and poultry industries, as well as a feedstock for biorefinery.
BIORESOURCE TECHNOLOGY
(2022)
Article
Fisheries
R. Magalhaes, N. Martins, F. Fontinha, A. Couto, C. R. Serra, R. A. Santos, E. Olsen, H. Peres, A. Oliva-Teles
Summary: The present study investigates the effects of different diet compositions on the oxidative status, histomorphology of liver and intestine, and intestinal microbiota modulation in gilthead sea bream juveniles. The results show that ARA-rich diets reduce liver and intestine lipid peroxidation, while DHA-rich diets increase the activity of antioxidant enzymes in the liver. Additionally, dietary starch improves the oxidative stress index in the liver and has positive effects on glutathione and lipid peroxidation in the intestine. Fish fed high starch diets also experience hepatocyte hypertrophy and alterations in nuclei position. Compared to DHA diets, ARA diets result in reduced diversity of intestinal microbiota. In conclusion, high dietary ARA provides protection to the liver and intestine of gilthead sea bream juveniles, and the balanced ratio of ARA/DHA in the diet has important effects on antioxidant status and intestinal microbiota diversity.
Article
Chemistry, Applied
Tao Ma, Shuyu Lu, Xinna Hu, Yi Song, Xiaosong Hu
Summary: This study aimed to investigate the impact of different oil types on cellulose nanocrystals (CNCs) and their digestion and gastrointestinal toxicity in vitro. The results showed that the addition of CNCs reduced the hydrolysis of free fatty acids (FFAs) in a high-fat food model, especially in emulsions with high unsaturation triglycerides. Additionally, CNCs had only a slight effect on reactive oxygen species and cytotoxicity, with no significant change in cell-layer integrity.
Article
Chemistry, Applied
Pascual Garcia-Perez, Gianluca Giuberti, Francesco Sestili, Domenico Lafiandra, Ermelinda Botticella, Luigi Lucini
Summary: This study evaluated the nutritional properties of wholegrain flours with different amylose/amylopectin ratios through in vitro starch digestion and large intestine fermentation. High-amylose flours showed higher resistant starch content and lower starch hydrolysis index. Metabolomics analysis revealed distinctive profiles between flours derived from different lines, with peptides, glycerophospholipids, polyphenols, and terpenoids identified as key markers. The high-amylose flour fermentates exhibited a rich bioactive profile, containing stilbenes, carotenoids, and saponins. These findings provide a basis for designing novel functional foods using high-amylose flours.
Article
Biochemistry & Molecular Biology
Rui Wang, Mei Li, Min Liu, Anqi Wang, Padraig Strappe, Chris Blanchard, Zhongkai Zhou
Summary: The Pickering emulsion was prepared using esterified debranched starch with short-chain fatty acids (SCFAs). The introduction of acyl groups improved the ability of starch to stabilize the emulsions, with butyrylated starch showing the highest emulsifying ability. The emulsions stabilized with butyrylated starch had better stability and smaller droplet sizes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Agronomy
Maryam Rahimi Jahangirlou, Gholam Abbas Akbari, Iraj Alahdadi, Saeid Soufizadeh, David Parsons
Summary: This study evaluated the concentration and composition of starch, protein, and oil in maize grain in response to different planting dates, irrigation intervals, and nitrogen rates. High nitrogen fertilization increased protein and nonessential amino acids, while high irrigation combined with high nitrogen rates increased oil content. The findings highlight the complex relationship between various factors and their impact on maize grain quality characteristics.
Article
Chemistry, Applied
Xiaoyang He, Liyang Zhou, Purnima Gunness, Vicky A. Solah, Qingjie Sun
Summary: This paper investigates the effect of lecithin on the complexation between starch and fatty acids. The results show that lecithin increases the viscosity of the complex, forms more V-type structures, and enhances the resistance to enzymatic hydrolysis. This research contributes to the scientific understanding of food ingredient interactions.
Article
Chemistry, Multidisciplinary
Ariel A. C. Toledo Hijo, Aureliano A. D. Meirelles, Guilherme J. Maximo, Rosiane L. Cunha, Marcelo Cristianini, Thiago S. . Leite, Jorge F. B. Pereira, Antonio J. A. Meirelles
Summary: This article presents a strategy to obtain highly stable emulsions using ionic liquid (IL) technology, with ILs derived from fatty acids and choline as an example. These ILs exhibited high emulsifier ability and antimicrobial effectiveness at low concentrations, leading to improved shelf life of emulsions.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)