GET4 is a novel driver gene in colorectal cancer that regulates the localization of BAG6, a nucleocytoplasmic shuttling protein

The novel driver gene ASAP2 is a potential druggable target in pancreatic cancer

(2021) Atsushi Fujii et al.   CANCER SCIENCE

Genomic basis for RNA alterations in cancer

(2020) Claudia Calabrese et al.   NATURE

Novel oncogene 5MP1 reprograms c-Myc translation initiation to drive malignant phenotypes in colorectal cancer

(2019) Kuniaki Sato et al.   EBioMedicine

Oncogenic splicing abnormalities induced by DEAD ‐Box Helicase 56 amplification in colorectal cancer

(2019) Yuta Kouyama et al.   CANCER SCIENCE

Chemoprevention of Colorectal Cancer

(2019) Bryson W. Katona et al.   GASTROENTEROLOGY

Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

(2019) NaNa Keum et al.   Nature Reviews Gastroenterology & Hepatology

PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer

(2019) Qun Li et al.   Science Advances

A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer

(2018) Tomoko Saito et al.   Nature Communications

CRMP5-associated GTPase (CRAG) Is a Candidate Driver Gene for Colorectal Cancer Carcinogenesis

(2018) DAI SHIMIZU et al.   ANTICANCER RESEARCH

Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35

(2017) Jee-Young Mock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma

(2016) H. Hirata et al.   CANCER RESEARCH

Overexpression of CXCR7 Is a Novel Prognostic Indicator in Gastric Cancer

(2016) Sho Nambara et al.   DIGESTIVE SURGERY

Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution

(2016) Ryutaro Uchi et al.   PLoS Genetics

Lysine-specific modifications of p53: a matter of life and death?

(2015) Diana Marouco et al.   Oncotarget

BAG6 regulates the quality control of a polytopic ERAD substrate

(2014) A. Payapilly et al.   JOURNAL OF CELL SCIENCE

BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy

(2014) S. Sebti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ArhGAP30 promotes p53 acetylation and function in colorectal cancer

(2014) Jilin Wang et al.   Nature Communications

p53 Acetylation: Regulation and Consequences

(2014) Sara Reed et al.   Cancers

Bag6/Bat3/Scythe: A novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation

(2013) Jin-Gu Lee et al.   BIOESSAYS

Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

(2013) Teresa Davoli et al.   CELL

BAG-6, a jack of all trades in health and disease

(2013) Janina Binici et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nuclear BAG6-UBL4A-GET4 Complex Mediates DNA Damage Signaling and Cell Death

(2013) Giedre Krenciute et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BAG6/BAT3: emerging roles in quality control for nascent polypeptides

(2012) H. Kawahara et al.   JOURNAL OF BIOCHEMISTRY

Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability

(2012) W. Wu et al.   JOURNAL OF CELL SCIENCE

A Novel, Non-Apoptotic Role for Scythe/BAT3: A Functional Switch between the Pro- and Anti-Proliferative Roles of p21 during the Cell Cycle

(2012) Sheila T. Yong et al.   PLoS One

Evaluation of normalization methods in mammalian microRNA-Seq data

(2012) L. X. Garmire et al.   RNA

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A Ubiquitin Ligase-Associated Chaperone Holdase Maintains Polypeptides in Soluble States for Proteasome Degradation

(2011) Qiuyan Wang et al.   MOLECULAR CELL

Protein targeting and degradation are coupled for elimination of mislocalized proteins

(2011) Tara Hessa et al.   NATURE

The impact of acetylation and deacetylation on the p53 pathway

(2011) Christopher L. Brooks et al.   Protein & Cell

A ribosome-associating factor chaperones tail-anchored membrane proteins

(2010) Malaiyalam Mariappan et al.   NATURE