Photodynamic therapy induces human esophageal carcinoma cell pyroptosis by targeting the PKM2/caspase-8/caspase-3/GSDME axis

The influence of photodynamic therapy on the Warburg effect in esophageal cancer cells

(2020) Junqing Gan et al.   LASERS IN MEDICAL SCIENCE

Alpinumisoflavone triggers GSDME ‐dependent pyroptosis in esophageal squamous cell carcinomas

(2020) Bin Zhang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Curcumin-Loaded Poly(L-lactide-co-glycolide) Microbubble-Mediated Sono-photodynamic Therapy in Liver Cancer Cells

(2020) Jiu-Xin Zhu et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma

(2019) Mengjiao Wu et al.   EBioMedicine

The role of pyroptosis in cancer: pro-cancer or pro-“host”?

(2019) Xiaojing Xia et al.   Cell Death & Disease

Epigenetics-Based Tumor Cells Pyroptosis for Enhancing the Immunological Effect of Chemotherapeutic Nanocarriers

(2019) Jin-Xuan Fan et al.   NANO LETTERS

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

(2019) Melanie Fritsch et al.   NATURE

Management of Liver Oligometastatic Esophageal Cancer: Overview and Critical Analysis of the Different Loco-Regional Treatments

(2019) Fabio Procopio et al.   Cancers

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

(2018) Nathalia M. de Vasconcelos et al.   CELL DEATH AND DIFFERENTIATION

Omega-3 docosahexaenoic acid induces pyroptosis cell death in triple-negative breast cancer cells

(2018) Nathalia Pizato et al.   Scientific Reports

Caloric Restriction Mimetic 2-Deoxyglucose Alleviated Inflammatory Lung Injury via Suppressing Nuclear Pyruvate Kinase M2–Signal Transducer and Activator of Transcription 3 Pathway

(2018) Kai Hu et al.   Frontiers in Immunology

Dihydroartemisinin Increases the Sensitivity of Photodynamic Therapy Via NF-κB/HIF-1α/VEGF Pathway in Esophageal Cancer Cell in vitro and in vivo

(2018) Yanjing Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis 

(2018) Bo Zhou et al.   CELL RESEARCH

Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection

(2018) Joseph Sarhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of lymphangiogenesis impairs antitumour effects of photodynamic therapy and checkpoint inhibitors in mice

(2017) Angelika Muchowicz et al.   EUROPEAN JOURNAL OF CANCER

Current and future treatment options for esophageal cancer in the elderly

(2017) Elfriede Bollschweiler et al.   EXPERT OPINION ON PHARMACOTHERAPY

Novel zinc phthalocyanine as a promising photosensitizer for photodynamic treatment of esophageal cancer

(2017) Weronika Kuzyniak et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Demethylating agent decitabine disrupts tumor-induced immune tolerance by depleting myeloid-derived suppressor cells

(2017) Jihao Zhou et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

(2017) Corey Rogers et al.   Nature Communications

Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo

(2017) Jian-Cai Tang et al.   Cancer Research and Treatment

Tanshinone ⅡA inhibits human esophageal cancer cell growth through miR-122-mediated PKM2 down-regulation

(2016) Hong-Sheng Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Pyroptosis

(2016) Lieselotte Vande Walle et al.   CURRENT BIOLOGY

ΔPK oncolytic activity includes modulation of the tumour cell milieu

(2016) Dominique Bollino et al.   JOURNAL OF GENERAL VIROLOGY

MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer

(2015) Kohei Taniguchi et al.   CANCER LETTERS

Targeting pyruvate kinase M2 contributes to radiosensitivity of non-small cell lung cancer cells in vitro and in vivo

(2015) Mao-Bin Meng et al.   CANCER LETTERS

Pyroptosis: Caspase-11 Unlocks the Gates of Death

(2015) Aude de Gassart et al.   IMMUNITY

Pyroptotic cell death defends against intracellular pathogens

(2015) Ine Jorgensen et al.   IMMUNOLOGICAL REVIEWS

Long-Term Follow-Up of a Community Assignment, One-Time Endoscopic Screening Study of Esophageal Cancer in China

(2015) Wen-Qiang Wei et al.   JOURNAL OF CLINICAL ONCOLOGY

The effect of ephrin-A1 on resistance to Photofrin-mediated photodynamic therapy in esophageal squamous cell carcinoma cells

(2015) Pei-Wen Yang et al.   LASERS IN MEDICAL SCIENCE

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

(2015) Roongruedee Chaiteerakij et al.   Cancer Medicine

Dihydroartemisinin Accentuates the Anti-Tumor Effects of Photodynamic Therapy via Inactivation of NF-κB in Eca109 and Ec9706 Esophageal Cancer Cells

(2014) Yan Jing Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Clinical outcome of photodynamic therapy in esophageal squamous cell carcinoma

(2014) Eunjue Yi et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Control of glioma cell death and differentiation by PKM2–Oct4 interaction

(2014) M Morfouace et al.   Cell Death & Disease

Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression

(2012) Michael S. Goldberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE