Machine learning and bioinformatics analysis revealed classification and potential treatment strategy in stage 3–4 NSCLC patients

A novel immunogenomic prognostic signature in lung squamous carcinoma

(2021) Jili Hou et al.   MEDICINE

Phase 2 study of bevacizumab plus carboplatin/nab-paclitaxel followed by bevacizumab plus nab‐paclitaxel for non‐squamous non‐small cell lung cancer with malignant pleural effusion

(2021) Motohiro Tamiya et al.   INVESTIGATIONAL NEW DRUGS

SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation

(2021) Esther Redin et al.   Journal for ImmunoTherapy of Cancer

A signature of tumor immune microenvironment genes associated with the prognosis of non‑small cell lung cancer

(2020) Jia Li et al.   ONCOLOGY REPORTS

Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer

(2020) Robin M. J. M. van Geel et al.   BRITISH JOURNAL OF CANCER

Double immune checkpoint blockade in advanced NSCLC

(2020) Annapaola Mariniello et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

The Use of Artificial Intelligence and Deep Machine Learning in Oncologic Histopathology

(2020) Ahmed S. Sultan et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Prognosis and personalized treatment prediction in TP53-mutant hepatocellular carcinoma: an in silico strategy towards precision oncology

(2020) Chen Yang et al.   BRIEFINGS IN BIOINFORMATICS

Random-forest algorithm based biomarkers in predicting prognosis in the patients with hepatocellular carcinoma

(2020) Lingyun Guo et al.   Cancer Cell International

Clinical significance and inflammatory landscapes of a novel recurrence-associated immune signature in early-stage lung adenocarcinoma

(2020) Chaoqi Zhang et al.   CANCER LETTERS

Identification of Prognostic Immune-Related Genes by Integrating mRNA Expression and Methylation in Lung Adenocarcinoma

(2020) Jie Zhu et al.   International Journal of Genomics

A Review About Pembrolizumab in First-Line Treatment of Advanced NSCLC: Focus on KEYNOTE Studies

(2020) Jialin Qu et al.   Cancer Management and Research

Lung metastases share common immune features regardless of primary tumor origin

(2020) Sandra García-Mulero et al.   Journal for ImmunoTherapy of Cancer

M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer

(2020) Eva M Garrido-Martin et al.   Journal for ImmunoTherapy of Cancer

Prognostic value of immune related genes in lung adenocarcinoma

(2020) Han Wang et al.   Oncology Letters

A gene expression signature of TREM2hi macrophages and γδ T cells predicts immunotherapy response

(2020) Donghai Xiong et al.   Nature Communications

Development of an Immune-Related Risk Signature for Predicting Prognosis in Lung Squamous Cell Carcinoma

(2020) Denggang Fu et al.   Frontiers in Genetics

Randomized phase II study of platinum-based chemotherapy plus controlled diet with or without metformin in patients with advanced non-small cell lung cancer

(2020) Youngjoo Lee et al.   LUNG CANCER

Characterization of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma to Aid Immunotherapy

(2020) Xinhai Zhang et al.   Molecular Therapy-Nucleic Acids

Tumor microenvironment characterization in gastric cancer identifies prognostic and immunotherapeutically relevant gene signatures

(2019) Dongqiang Zeng et al.   Cancer Immunology Research

Comparable Genomic Copy Number Aberrations Differ across Astrocytoma Malignancy Grades

(2019) Nives Pećina-Šlaus et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miR-142-5p regulates pancreatic cancer cell proliferation and apoptosis by regulation of RAP1A

(2019) Rong Yao et al.   PATHOLOGY RESEARCH AND PRACTICE

The role of combination chemo-immunotherapy in advanced non-small cell lung cancer

(2019) Danilo Rocco et al.   Expert Review of Anticancer Therapy

Molecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer

(2019) Alessandro Leonetti et al.   DRUG RESISTANCE UPDATES

Non–Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment

(2019) Narjust Duma et al.   MAYO CLINIC PROCEEDINGS

Development and validation of a CIMP-associated prognostic model for hepatocellular carcinoma

(2019) Ganxun Li et al.   EBioMedicine

Antigen presentation and tumor immunogenicity in cancer immunotherapy response prediction

(2019) Shixiang Wang et al.   eLife

Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges

(2019) Shigao Huang et al.   CANCER LETTERS

TP53,STK11andEGFRMutations Predict Tumor Immune Profile and the Response to anti-PD-1 in Lung Adenocarcinoma

(2018) Jerome Biton et al.   CLINICAL CANCER RESEARCH

XGBFEMF: An XGBoost-based Framework for Essential Protein Prediction

(2018) Jiancheng Zhong et al.   IEEE TRANSACTIONS ON NANOBIOSCIENCE

Targeted Therapy and Immunotherapy in the Treatment of Non–Small Cell Lung Cancer

(2018) Girish S. Shroff et al.   RADIOLOGIC CLINICS OF NORTH AMERICA

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

(2018) Noam Auslander et al.   NATURE MEDICINE

IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade

(2017) Mark Ayers et al.   JOURNAL OF CLINICAL INVESTIGATION

The Potential of Combined Immunotherapy and Antiangiogenesis for the Synergistic Treatment of Advanced NSCLC

(2017) Christian Manegold et al.   Journal of Thoracic Oncology

Precision Diagnosis and Treatment for Advanced Non–Small-Cell Lung Cancer

(2017) Martin Reck et al.   NEW ENGLAND JOURNAL OF MEDICINE

Knockdown of CREB1 inhibits tumor growth of human gastric cancer in vitro and in vivo

(2017) Min Rao et al.   ONCOLOGY REPORTS

Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data

(2017) Julien Racle et al.   eLife

Identification of HSPA8 as a candidate biomarker for endometrial carcinoma by using iTRAQ-based proteomic analysis

(2016) Yu Zhang et al.   OncoTargets and Therapy

Phase I and pharmacokinetics/pharmacodynamics study of the MEK inhibitor RO4987655 in Japanese patients with advanced solid tumors

(2015) Shinji Nakamichi et al.   INVESTIGATIONAL NEW DRUGS

Correlating chemical sensitivity and basal gene expression reveals mechanism of action

(2015) Matthew G Rees et al.   Nature Chemical Biology

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Γ-Ionizing radiation-induced activation of the EGFR–p38/ERK–STAT3/CREB-1–EMT pathway promotes the migration/invasion of non-small cell lung cancer cells and is inhibited by podophyllotoxin acetate

(2015) Jeong Hyun Cho et al.   TUMOR BIOLOGY

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

miRDB: an online resource for microRNA target prediction and functional annotations

(2014) Nathan Wong et al.   NUCLEIC ACIDS RESEARCH

Genotyping and Genomic Profiling of Non–Small-Cell Lung Cancer: Implications for Current and Future Therapies

(2013) Tianhong Li et al.   JOURNAL OF CLINICAL ONCOLOGY

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?

(2012) Jane L. Messina et al.   Scientific Reports

miRTarBase: a database curates experimentally validated microRNA–target interactions

(2010) Sheng-Da Hsu et al.   NUCLEIC ACIDS RESEARCH