CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles

Targeting herpes simplex virus with CRISPR–Cas9 cures herpetic stromal keratitis in mice

(2021) Di Yin et al.   NATURE BIOTECHNOLOGY

Lentiviral delivery of co-packaged Cas9 mRNA and a Vegfa-targeting guide RNA prevents wet age-related macular degeneration in mice

(2021) Sikai Ling et al.   Nature Biomedical Engineering

Adenine Base Editor Ribonucleoproteins Delivered by Lentivirus-Like Particles Show High On-Target Base Editing and Undetectable RNA Off-Target Activities

(2021) Pin Lyu et al.   CRISPR Journal

Lentiviral Capsid-Mediated Streptococcus pyogenes Cas9 Ribonucleoprotein Delivery for Efficient and Safe Multiplex Genome Editing

(2021) Zuyan Lu et al.   CRISPR Journal

Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair

(2021) Jonathan J. Wilde et al.   CELL

Recurrent Genetic Abnormalities in Human Pluripotent Stem Cells: Definition and Routine Detection in Culture Supernatant by Targeted Droplet Digital PCR

(2020) Said Assou et al.   Stem Cell Reports

Gene conversion following CRISPR/Cas9 DNA cleavage: an overlooked effect

(2020) Gaetan Burgio   GENE THERAPY

Pipeline for the Generation and Characterization of Transgenic Human Pluripotent Stem Cells Using the CRISPR/Cas9 Technology

(2020) Joffrey Mianné et al.   Cells

A simple, quick, and efficient CRISPR/Cas9 genome editing method for human induced pluripotent stem cells

(2020) Bing-chuan Geng et al.   ACTA PHARMACOLOGICA SINICA

Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos

(2020) Michael V. Zuccaro et al.   CELL

Generation of the induced pluripotent stem cell line UHOMi002-A from peripheral blood mononuclear cells of a healthy male donor

(2020) Mathieu Fieldes et al.   Stem Cell Research

Delivering SaCas9 mRNA by lentivirus-like bionanoparticles for transient expression and efficient genome editing

(2019) Baisong Lu et al.   NUCLEIC ACIDS RESEARCH

Induced pluripotent stem cells in disease modelling and drug discovery

(2019) R. Grant Rowe et al.   NATURE REVIEWS GENETICS

CRISPResso2 provides accurate and rapid genome editing sequence analysis

(2019) Kendell Clement et al.   NATURE BIOTECHNOLOGY

Guidelines for optimized gene knockout using CRISPR/Cas9

(2019) Claude Van Campenhout et al.   BIOTECHNIQUES

Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination

(2019) Renata M. Martin et al.   Cell Stem Cell

Fluorescent Gene Tagging of Transcriptionally Silent Genes in hiPSCs

(2019) Brock Roberts et al.   Stem Cell Reports

TraFo-CRISPR: Enhanced Genome Engineering by Transient Foamy Virus Vector-Mediated Delivery of CRISPR/Cas9 Components

(2019) Fabian Lindel et al.   Molecular Therapy-Nucleic Acids

p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells

(2018) Robert J. Ihry et al.   NATURE MEDICINE

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response

(2018) Emma Haapaniemi et al.   NATURE MEDICINE

Ma et al. reply

(2018) Hong Ma et al.   NATURE

Inter-homologue repair in fertilized human eggs?

(2018) Dieter Egli et al.   NATURE

Large deletions induced by Cas9 cleavage

(2018) Fatwa Adikusuma et al.   NATURE

Highly efficient genome editing via CRISPR–Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression

(2018) Xiao-Lan Li et al.   NUCLEIC ACIDS RESEARCH

Generation of the induced pluripotent stem cell line UHOMi001-A from a patient with mutations in CCDC40 gene causing Primary Ciliary Dyskinesia (PCD)

(2018) Ahmed Engi et al.   Stem Cell Research

Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporation

(2018) Xiaoyun Xu et al.   Scientific Reports

Transient retrovirus-based CRISPR/Cas9 all-in-one particles for efficient, targeted gene knockout

(2018) Yvonne Knopp et al.   Molecular Therapy-Nucleic Acids

Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency

(2017) Marella D Canny et al.   NATURE BIOTECHNOLOGY

Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection

(2017) Katie A. Mitzelfelt et al.   Stem Cell Reports

Integrase-Deficient Lentiviral Vector as an All-in-One Platform for Highly Efficient CRISPR/Cas9-Mediated Gene Editing

(2017) Pavel I. Ortinski et al.   Molecular Therapy-Methods & Clinical Development

Improved delivery of Cas9 protein/gRNA complexes using lipofectamine CRISPRMAX

(2016) Xin Yu et al.   BIOTECHNOLOGY LETTERS

Induced Pluripotent Stem Cells Meet Genome Editing

(2016) Dirk Hockemeyer et al.   Cell Stem Cell

DNA repair mechanisms in embryonic stem cells

(2016) Xuemei Fu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases

(2016) Mark J Osborn et al.   MOLECULAR THERAPY

Induced pluripotent stem cell technology: a decade of progress

(2016) Yanhong Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Generation of knock-in primary human T cells using Cas9 ribonucleoproteins

(2015) Kathrin Schumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles

(2015) Anne Prel et al.   Molecular Therapy-Methods & Clinical Development

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

(2014) S. Kim et al.   GENOME RESEARCH

Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR–Cas platform

(2014) K. Yoshimi et al.   Nature Communications

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

(2014) Ulrike Mock et al.   Scientific Reports

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

(2013) Prashant Mali et al.   NATURE BIOTECHNOLOGY

The role of DNA repair in the pluripotency and differentiation of human stem cells

(2012) Clarissa Ribeiro Reily Rocha et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

DNA-Damage Response in Tissue-Specific and Cancer Stem Cells

(2011) Cedric Blanpain et al.   Cell Stem Cell