Nano-immunosorbent assay based on Cas12a/crRNA for ultra-sensitive protein detection

A CRISPR/Cas9 eraser strategy for contamination‐free PCR end‐point detection

(2021) Wei Lin et al.   BIOTECHNOLOGY AND BIOENGINEERING

Gold nanoparticles doped metal-organic frameworks as near-infrared light-enhanced cascade nanozyme against hypoxic tumors

(2020) Xinli Liu et al.   Nano Research

Dynamic Aqueous Multiphase Reaction System for One-Pot CRISPR-Cas12a-Based Ultrasensitive and Quantitative Molecular Diagnosis

(2020) Kun Yin et al.   ANALYTICAL CHEMISTRY

High-throughput and all-solution phase African Swine Fever Virus (ASFV) detection using CRISPR-Cas12a and fluorescence based point-of-care system

(2020) Qian He et al.   BIOSENSORS & BIOELECTRONICS

Massively multiplexed nucleic acid detection with Cas13

(2020) Cheri M. Ackerman et al.   NATURE

CRISPR–Cas12-based detection of SARS-CoV-2

(2020) James P. Broughton et al.   NATURE BIOTECHNOLOGY

Applying CRISPR-Cas12a as a Signal Amplifier to Construct Biosensors for Non-DNA Targets in Ultralow Concentrations

(2020) Junjie Li et al.   ACS Sensors

CUT-LAMP: Contamination-Free Loop-Mediated Isothermal Amplification Based on the CRISPR/Cas9 Cleavage

(2020) Yijuan Bao et al.   ACS Sensors

Allosteric Probe-Initiated Wash-Free Method for Sensitive Extracellular Vesicle Detection through Dual Cycle-Assisted CRISPR-Cas12a

(2020) Xianxian Zhao et al.   ACS Sensors

Point-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities

(2020) Jeanne E. van Dongen et al.   BIOSENSORS & BIOELECTRONICS

Aptamer-based CRISPR/Cas12a assay for the ultrasensitive detection of extracellular vesicle proteins

(2020) Huilan Li et al.   TALANTA

Engineering of CRISPR-Cas12b for human genome editing

(2019) Jonathan Strecker et al.   Nature Communications

Near-infrared upconversion–activated CRISPR-Cas9 system: A remote-controlled gene editing platform

(2019) Yongchun Pan et al.   Science Advances

A self-powered microfluidic chip integrated with fluorescent microscopic counting for biomarkers assay

(2019) Jian Yang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Uracil-Mediated New Photospacer-Adjacent Motif of Cas12a To Realize Visualized DNA Detection at the Single-Copy Level Free from Contamination

(2019) Cheng Qian et al.   ANALYTICAL CHEMISTRY

The human secretome

(2019) Mathias Uhlén et al.   Science Signaling

Rapid identification of urinary tract infections based on ultrasensitive bacteria detection using volumetric bar-chart chip

(2019) Ting Huang et al.   SENSORS AND ACTUATORS B-CHEMICAL

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

(2019) Mindong Liang et al.   Nature Communications

CRISPR/Cas13a Signal Amplification Linked Immunosorbent Assay for Femtomolar Protein Detection

(2019) Qian Chen et al.   ANALYTICAL CHEMISTRY

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic-Acid Targets

(2019) Ying Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

Aptamer-based nanobiosensors

(2016) Yeon Seok Kim et al.   BIOSENSORS & BIOELECTRONICS

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

(2015) Bernd Zetsche et al.   CELL

A novel aptamer-functionalized MoS2 nanosheet fluorescent biosensor for sensitive detection of prostate specific antigen

(2014) Rong-Mei Kong et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Development of Atom Transfer Radical Polymer-Modified Gold Nanoparticle-Based Enzyme-Linked Immunosorbent Assay (ELISA)

(2014) Feng Chen et al.   ANALYTICAL CHEMISTRY

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Paper-Based ELISA

(2010) Chao-Min Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrasensitive electrochemical aptasensor for thrombin based on the amplification of aptamer–AuNPs–HRP conjugates

(2010) Jie Zhao et al.   BIOSENSORS & BIOELECTRONICS