AMPK inhibitor BML-275 induces neuroprotection through decreasing cyt c and AIF expression after transient brain ischemia

Natural medicine in neuroprotection for ischemic stroke: Challenges and prospective

(2020) Tao Tao et al.   PHARMACOLOGY & THERAPEUTICS

Therapeutic effects of JLX-001 on ischemic stroke by inducing autophagy via AMPK-ULK1 signaling pathway in rats

(2019) Lu-yao Ao et al.   BRAIN RESEARCH BULLETIN

Neuroprotective effects of resveratrol against oxygen glucose deprivation induced mitochondrial dysfunction by activation of AMPK in SH-SY5Y cells with 3D gelatin scaffold

(2019) Chien-Hung Lin et al.   BRAIN RESEARCH

Remote limb ischemic postconditioning protects against cerebral ischemia-reperfusion injury by activating AMPK-dependent autophagy

(2018) Hao Guo et al.   BRAIN RESEARCH BULLETIN

Ginkgolide K promotes astrocyte proliferation and migration after oxygen-glucose deprivation via inducing protective autophagy through the AMPK/mTOR/ULK1 signaling pathway

(2018) Ying Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ezetimibe, a NPC1L1 inhibitor, attenuates neuronal apoptosis through AMPK dependent autophagy activation after MCAO in rats

(2018) Jing Yu et al.   EXPERIMENTAL NEUROLOGY

Hispidulin Protects Against Focal Cerebral Ischemia Reperfusion Injury in Rats

(2018) Pengpeng An et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Autophagy in hemorrhagic stroke: Mechanisms and clinical implications

(2018) Haiying Li et al.   PROGRESS IN NEUROBIOLOGY

Neuroprotective effect of linagliptin against cuprizone-induced demyelination and behavioural dysfunction in mice: A pivotal role of AMPK/SIRT1 and JAK2/STAT3/NF-κB signalling pathway modulation

(2018) Eman M. Elbaz et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Recent advances in the development of neuroprotective agents and therapeutic targets in the treatment of cerebral ischemia

(2018) Yin Luo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mesenchymal stem cells-derived IL-6 activates AMPK/mTOR signaling to inhibit the proliferation of reactive astrocytes induced by hypoxic-ischemic brain damage

(2018) Mulan He et al.   EXPERIMENTAL NEUROLOGY

Design, synthesis, and biological activity of 4-(imidazo[1,2- b ]pyridazin-3-yl)-1 H -pyrazol-1-yl-phenylbenzamide derivatives as BCR–ABL kinase inhibitors

(2016) Liming Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pretreatment of rats with increased bioavailable berberine attenuates cerebral ischemia-reperfusion injury via down regulation of adenosine-5′monophosphate kinase activity

(2016) Weijia Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The neuroprotection of Sinomenine against ischemic stroke in mice by suppressing NLRP3 inflammasome via AMPK signaling

(2016) Jing Qiu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice

(2015) Catherine I. Rousset et al.   JOURNAL OF NEUROCHEMISTRY

A combination of four active compounds alleviates cerebral ischemia-reperfusion injury in correlation with inhibition of autophagy and modulation of AMPK/mTOR and JNK pathways

(2014) Zhongshun Guo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Role of vinpocetine in cerebrovascular diseases

(2014) Sazal Patyar et al.   Pharmacological Reports

Neuronal autophagy in cerebral ischemia – a potential target for neuroprotective strategies?

(2014) Bożena Gabryel et al.   Pharmacological Reports

Past strategies and future directions for identifying AMP-activated protein kinase (AMPK) modulators

(2014) Sarah E. Sinnett et al.   PHARMACOLOGY & THERAPEUTICS

Silent Information Regulator 1 Protects the Brain Against Cerebral Ischemic Damage

(2013) M. Hernandez-Jimenez et al.   STROKE

AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1

(2012) Ujval Anilkumar et al.   JOURNAL OF NEUROCHEMISTRY

Delayed administration of a PTEN inhibitor BPV improves functional recovery after experimental stroke

(2012) L. Mao et al.   NEUROSCIENCE

Ischemic Stroke and Glucose Intolerance: a Review of the Evidence and Exploration of Novel Therapeutic Targets

(2011) Shinichi Harada et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Preconditioning induces sustained neuroprotection by downregulation of adenosine 5′-monophosphate-activated protein kinase

(2011) V.R. Venna et al.   NEUROSCIENCE

Adenosine monophosphate activated protein kinase inhibition is protective in both sexes after experimental stroke

(2010) Jun Li et al.   NEUROSCIENCE LETTERS

New Approaches to Neuroprotective Drug Development

(2010) M. Fisher   STROKE

Methazolamide and Melatonin Inhibit Mitochondrial Cytochrome C Release and Are Neuroprotective in Experimental Models of Ischemic Injury

(2009) Xin Wang et al.   STROKE

Caspase-Independent Programmed Cell Death Following Ischemic Stroke

(2008) Benjamin B. Cho et al.   JOURNAL OF INVESTIGATIVE SURGERY