A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency

Pathophysiology of psoriasis: A review

(2021) Keiichi Yamanaka et al.   JOURNAL OF DERMATOLOGY

2,4-Dimethoxy-6-Methylbenzene-1,3-diol, a Benzenoid From Antrodia cinnamomea, Mitigates Psoriasiform Inflammation by Suppressing MAPK/NF-κB Phosphorylation and GDAP1L1/Drp1 Translocation

(2021) Shih-Yi Chuang et al.   Frontiers in Immunology

S1PR4‐dependent CCL2 production promotes macrophage recruitment in a murine psoriasis model

(2020) Christian Schuster et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Comparison of Biologics and Oral Treatments for Plaque Psoriasis

(2020) April W. Armstrong et al.   JAMA Dermatology

Development of flavanone and its derivatives as topical agents against psoriasis: The prediction of therapeutic efficiency through skin permeation evaluation and cell-based assay

(2020) Ahmed Alalaiwe et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Facile skin targeting of a thalidomide analog containing benzyl chloride moiety alleviates experimental psoriasis via the suppression of MAPK/NF-κB/AP-1 phosphorylation in keratinocytes

(2020) Kai-Wei Tang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Induction of Regulatory T Cells and Correction of Cytokine Disbalance by Short-Chain Fatty Acids: Implications for Psoriasis Therapy

(2020) Agatha Schwarz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Natural Compound Mixture, Containing Emodin, Genipin, Chlorogenic Acid, Cimigenoside, and Ginsenoside Rb1, Ameliorates Psoriasis-Like Skin Lesions by Suppressing Inflammation and Proliferation in Keratinocytes

(2020) Uy Thai Nguyen et al.   Evidence-based Complementary and Alternative Medicine

Role of Innate Immune Cells in Psoriasis

(2020) Yuki Sato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

What we already know about rhubarb: a comprehensive review

(2020) Hong Xiang et al.   Chinese Medicine

Rhein, An Anthraquinone Drug, Suppresses the NLRP3 Inflammasome and Macrophage Activation in Urate Crystal-Induced Gouty Inflammation

(2019) Wan-Chun Chang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Topical Application of a Dual ABC Transporter Substrate and NF-κB Inhibitor Blocks Multiple Sources of Cutaneous Inflammation in Mouse Skin

(2019) Luowei Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Risk Factors for the Development of Psoriasis

(2019) Koji Kamiya et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TRIM27 promotes the proliferation and inflammation factor production induced by IL-6 by activating STAT3 signaling in HaCaT cells

(2019) Xiao Miao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cutaneous delivery of [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, mitigates psoriasiform lesion by blocking MAPK/NF-κB/AP-1 activation

(2019) Jing-Ru Weng et al.   BIOMEDICINE & PHARMACOTHERAPY

PSORI-CM02 formula alleviates imiquimod-induced psoriasis via affecting macrophage infiltration and polarization

(2019) Leng Li et al.   LIFE SCIENCES

The IL-13/periostin/IL-24 pathway causes epidermal barrier dysfunction in allergic skin inflammation

(2018) Yasutaka Mitamura et al.   ALLERGY

Psoriasis: from Pathogenesis to Targeted Therapies

(2018) Curdin Conrad et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Molecular mechanisms of anti-inflammatory effect of chrysophanol, an active component of AST2017-01 on atopic dermatitis in vitro models

(2018) Hyun-Ja Jeong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Eosinophils Accelerate Pathogenesis of Psoriasis by Supporting an Inflammatory Milieu that Promotes Neutrophil Infiltration

(2018) Hee Joo Kim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Interplay Between Keratinocytes and Immune Cells in the Pathogenesis of Psoriasis

(2018) Cristina Albanesi et al.   Frontiers in Immunology

The active compounds derived from Psoralea corylifolia for photochemotherapy against psoriasis-like lesions: The relationship between structure and percutaneous absorption

(2018) Ahmed Alalaiwe et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Tight Junction barriers in human hair follicles – role of claudin-1

(2018) Michaela Zorn-Kruppa et al.   Scientific Reports

Psoriasis: Keratinocytes or Immune Cells – Which Is the Trigger?

(2018) Farida Benhadou et al.   DERMATOLOGY

A Water-Soluble Extract from Actinidia arguta Ameliorates Psoriasis-Like Skin Inflammation in Mice by Inhibition of Neutrophil Infiltration

(2018) Hyun-keun Kim et al.   Nutrients

Quantitative structure-skin permeability relationships

(2017) Ivanka Tsakovska et al.   TOXICOLOGY

Rhein attenuates inflammation through inhibition of NF-κB and NALP3 inflammasome in vivo and in vitro

(2017) Hui Ge et al.   Drug Design Development and Therapy

Elucidating the Skin Delivery of Aglycone and Glycoside Flavonoids: How the Structures Affect Cutaneous Absorption

(2017) Shih-Yi Chuang et al.   Nutrients

Advances in bio-active constituents, pharmacology and clinical applications of rhubarb

(2017) Yu-Jie Cao et al.   Chinese Medicine

Therapeutic targeting of Toll-like receptors: a review of Toll-like receptors and their signaling pathways in psoriasis

(2016) Farzaneh Rahmani et al.   Expert Review of Clinical Immunology

A systematic review of worldwide epidemiology of psoriasis

(2016) I.M. Michalek et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Vehicle effects on human stratum corneum absorption and skin penetration

(2016) Alissa Zhang et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

In vitro human skin penetration model for organophosphorus compounds with different physicochemical properties

(2016) L. Thors et al.   TOXICOLOGY IN VITRO

A Comprehensive and System Review for the Pharmacological Mechanism of Action of Rhein, an Active Anthraquinone Ingredient

(2016) Hao Sun et al.   Frontiers in Pharmacology

Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by downregulating inflammation

(2015) Yue Sun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Skin Diseases Associated with the Depletion of Stratum Corneum Lipids and Stratum Corneum Lipid Substitution Therapy

(2015) Fitsum F. Sahle et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosedin vitroon canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship

(2014) J. E. Riviere et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Prodrug Strategies for Enhancing the Percutaneous Absorption of Drugs

(2014) David N'Da   MOLECULES

The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety

(2014) Martins Ekor   Frontiers in Pharmacology

Photoprotective and antioxidant effects of Rhubarb: inhibitory action on tyrosinase and tyrosine kinase activities and TNF-α, IL-1α and α-MSH production in human melanocytes

(2013) Jéssica PS Silveira et al.   BMC Complementary and Alternative Medicine

Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like Skin Inflammation in Mice

(2013) Snehlata Kumari et al.   IMMUNITY

Therapeutic depletion of myeloid lineage leukocytes in patients with generalized pustular psoriasis indicates a major role for neutrophils in the immunopathogenesis of psoriasis

(2013) Shigaku Ikeda et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Anti-inflammatory properties of anthraquinones and their relationship with the regulation of P-glycoprotein function and expression

(2012) Ran Joo Choi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Solar UV radiation reduces the barrier function of human skin

(2012) K. Biniek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptors

(2011) Eva Marie Y. Moresco et al.   CURRENT BIOLOGY

Correlating percutaneous absorption with physicochemical parametersin vivoin man: agricultural, steroid, and other organic compounds

(2009) Ali Alikhan et al.   JOURNAL OF APPLIED TOXICOLOGY

Increased expression of IL-12p70 and IL-23 by multiple dendritic cell and macrophage subsets in plaque psoriasis

(2009) Nikhil Yawalkar et al.   JOURNAL OF DERMATOLOGICAL SCIENCE