Intelligent photothermal dendritic cells restart the cancer immunity cycle through enhanced immunogenic cell death

Dual mitigation of immunosuppression combined with photothermal inhibition for highly effective primary tumor and metastases therapy

(2021) Ju Huang et al.   BIOMATERIALS

New perspectives in genetics and targeted therapy for blastic plasmacytoid dendritic cell neoplasm

(2020) Xiang Zhang et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response

(2020) Xiang Yu et al.   Nature Communications

Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma

(2020) Natalia Trempolec et al.   Cancers

T-Cell based therapies for overcoming neuroanatomical and immunosuppressive challenges within the glioma microenvironment

(2020) Darwin Kwok et al.   JOURNAL OF NEURO-ONCOLOGY

Second Near‐Infrared Photothermal Semiconducting Polymer Nanoadjuvant for Enhanced Cancer Immunotherapy

(2020) Jingchao Li et al.   ADVANCED MATERIALS

Molecular Motion in Aggregates: Manipulating TICT for Boosting Photothermal Theranostics

(2019) Shunjie Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scaffolds biomimicking macrophages for a glioblastoma NIR-Ib imaging guided photothermal therapeutic strategy by crossing Blood-Brain Barrier

(2019) Jiazheng Lai et al.   BIOMATERIALS

Frequency stabilization and noise-induced spectral narrowing in resonators with zero dispersion

(2019) L. Huang et al.   Nature Communications

Induction of Tolerance and Immunity by Dendritic Cells: Mechanisms and Clinical Applications

(2019) Jitka Fucikova et al.   Frontiers in Immunology

Enhancing Both Biodegradability and Efficacy of Semiconducting Polymer Nanoparticles for Photoacoustic Imaging and Photothermal Therapy

(2018) Yan Lyu et al.   ACS Nano

A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments

(2018) Kevin C. Barry et al.   NATURE MEDICINE

Combination Treatment of Stereotactic Body Radiation Therapy and Immature Dendritic Cell Vaccination for Augmentation of Local and Systemic Effects

(2018) Chul Won Choi et al.   Cancer Research and Treatment

Tumor Necrosis Factor α and Regulatory T Cells in Oncoimmunology

(2018) Benoît L. Salomon et al.   Frontiers in Immunology

Towards superior dendritic-cell vaccines for cancer therapy

(2018) Mansi Saxena et al.   Nature Biomedical Engineering

Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

(2018) Yuzhu Hou et al.   IMMUNITY

Near-infrared fluorescence imaging in the largely unexplored window of 900-1,000 nm

(2018) Guanjun Deng et al.   Theranostics

Cell-Membrane Immunotherapy Based on Natural Killer Cell Membrane Coated Nanoparticles for the Effective Inhibition of Primary and Abscopal Tumor Growth

(2018) Guanjun Deng et al.   ACS Nano

Dendrimer-Based Lipid Nanoparticles Deliver Therapeutic FAH mRNA to Normalize Liver Function and Extend Survival in a Mouse Model of Hepatorenal Tyrosinemia Type I

(2018) Qiang Cheng et al.   ADVANCED MATERIALS

Effective and Targeted Human Orthotopic Glioblastoma Xenograft Therapy via a Multifunctional Biomimetic Nanomedicine

(2018) Yan Zou et al.   ADVANCED MATERIALS

Dendritic Cell Cancer Therapy: Vaccinating the Right Patient at the Right Time

(2018) Wouter W. van Willigen et al.   Frontiers in Immunology

Integrating Next-Generation Dendritic Cell Vaccines into the Current Cancer Immunotherapy Landscape

(2017) Abhishek D. Garg et al.   TRENDS IN IMMUNOLOGY

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells

(2017) Michel Enamorado et al.   Nature Communications

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

(2017) Claire Vanpouille-Box et al.   Nature Communications

Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells

(2017) Marco Ruella et al.   Cancer Discovery

Nanoparticle-mediated dual delivery of resveratrol and DAP5 ameliorates kidney ischemia/reperfusion injury by inhibiting cell apoptosis and inflammation

(2017) Yong Xu et al.   Oncotarget

Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer

(2017) Jung-Eun Jang et al.   Cell Reports

Near-Infrared Polymeric Nanoparticles with High Content of Cyanine for Bimodal Imaging and Photothermal Therapy

(2016) Wenhai Lin et al.   ACS Applied Materials & Interfaces

Self-adjuvanted nanovaccine for cancer immunotherapy: Role of lysosomal rupture-induced ROS in MHC class I antigen presentation

(2016) Ce Wang et al.   BIOMATERIALS

Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming

(2016) M. E. Rodriguez-Ruiz et al.   CANCER RESEARCH

Dendritic Cell-Based Immunotherapy: State of the Art and Beyond

(2016) K. F. Bol et al.   CLINICAL CANCER RESEARCH

Semiconducting Polymer Nanobioconjugates for Targeted Photothermal Activation of Neurons

(2016) Yan Lyu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ochratoxin A mediates MAPK activation, modulates IL-2 and TNF-α mRNA expression and induces apoptosis by mitochondria-dependent and mitochondria-independent pathways in human H9 T cells

(2016) Youssef Darif et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Dendritic Cells and Cancer Immunity

(2016) Alycia Gardner et al.   TRENDS IN IMMUNOLOGY

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

(2016) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Antigen-Loaded Upconversion Nanoparticles for Dendritic Cell Stimulation, Tracking, and Vaccination in Dendritic Cell-Based Immunotherapy

(2015) Jian Xiang et al.   ACS Nano

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

(2015) Edgar Pérez-Herrero et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Nanoparticle biointerfacing by platelet membrane cloaking

(2015) Che-Ming J. Hu et al.   NATURE

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2–dependent adult T-cell leukemia

(2015) Meili Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1

(2015) E. Vacchelli et al.   SCIENCE

Use of enhanced interleukin-2 formulations for improved immunotherapy against cancer

(2014) Rodney A Rosalia et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

CD28–CD80 Interactions Control Regulatory T Cell Motility and Immunological Synapse Formation

(2014) Timothy J. Thauland et al.   JOURNAL OF IMMUNOLOGY

Caspase-3 is Involved in IFN-γ- and TNF-α-Mediated MIN6 Cells Apoptosis via NF-κB/Bcl-2 Pathway

(2013) Zhao-hui Cao et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells

(2013) Yuting Ma et al.   IMMUNITY

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

TNF-α Has Tropic Rather than Apoptotic Activity in Human Hematopoietic Progenitors: Involvement of TNF Receptor-1 and Caspase-8

(2012) Keren Mizrahi et al.   STEM CELLS

PROVENGE (Sipuleucel-T) in Prostate Cancer: The First FDA-Approved Therapeutic Cancer Vaccine

(2011) M. A. Cheever et al.   CLINICAL CANCER RESEARCH

Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice

(2011) W. Joost Lesterhuis et al.   JOURNAL OF CLINICAL INVESTIGATION

Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials

(2011) Jitka Fučíková et al.   Journal of Translational Medicine

Histone deacetylase inhibitors cooperate with IFN-γ to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8

(2009) S Häcker et al.   ONCOGENE