A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury

Acceleration of chondrogenic differentiation of human mesenchymal stem cells by sustained growth factor release in 3D graphene oxide incorporated hydrogels

(2020) He Shen et al.   Acta Biomaterialia

HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia

(2020) Shutian Zhang et al.   Journal of Neuroinflammation

Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model

(2020) Dominique R. Smith et al.   TISSUE ENGINEERING PART A

A novel hydrogel-based treatment for complete transection spinal cord injury repair is driven by microglia/macrophages repopulation

(2020) Dezun Ma et al.   BIOMATERIALS

Treatment of severe sepsis with nanoparticulate cell-free DNA scavengers

(2020) Jianati Dawulieti et al.   Science Advances

Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury

(2020) Hong Fan et al.   Journal of Neuroinflammation

Lentiviral Interleukin-10 Gene Therapy Preserves Fine Motor Circuitry and Function After a Cervical Spinal Cord Injury in Male and Female Mice

(2020) Jessica Y. Chen et al.   Neurotherapeutics

Locally Controlled Diffusive Release of Bone Morphogenetic Protein-2 Using Micropatterned Gelatin Methacrylate Hydrogel Carriers

(2020) Myong-Hee Yi et al.   BioChip Journal

Transplantation of adult spinal cord grafts into spinal cord transected rats improves their locomotor function

(2019) He Shen et al.   Science China-Life Sciences

Tuned Cationic Dendronized Polymer: Molecular Scavenger for Rheumatoid Arthritis Treatment

(2019) Bo Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient in vivo bone formation by BMP-2 engineered human mesenchymal stem cells encapsulated in a projection stereolithographically fabricated hydrogel scaffold

(2019) Hang Lin et al.   Stem Cell Research & Therapy

Tissue‐Engineered Neural Network Graft Relays Excitatory Signal in the Completely Transected Canine Spinal Cord

(2019) Bi‐Qin Lai et al.   Advanced Science

Epidermal growth factor receptor-extracellular-regulated kinase blockade upregulates TRIM32 signaling cascade and promotes neurogenesis after spinal cord injury

(2019) Weiwei Xue et al.   STEM CELLS

Toll-like receptor 4 (TLR4) influences the glial reaction in the spinal cord and the neural response to injury following peripheral nerve crush

(2019) Patrícia Ribeiro et al.   BRAIN RESEARCH BULLETIN

Inhibiting high mobility group box-1 reduces early spinal cord edema and attenuates astrocyte activation and aquaporin-4 expression after spinal cord injury in rats

(2018) Lin Sun et al.   JOURNAL OF NEUROTRAUMA

Local Immunomodulation with Anti-inflammatory Cytokine-Encoding Lentivirus Enhances Functional Recovery after Spinal Cord Injury

(2018) Jonghyuck Park et al.   MOLECULAR THERAPY

Spinal Cord Injury Scarring and Inflammation: Therapies Targeting Glial and Inflammatory Responses

(2018) Michael B. Orr et al.   Neurotherapeutics

Traumatic Spinal Injury: Global Epidemiology and Worldwide Volume

(2018) Ramesh Kumar et al.   World Neurosurgery

Regulation of Inflammatory Cytokines for Spinal Cord Injury Repair Through Local Delivery of Therapeutic Agents

(2018) Hao Ren et al.   Advanced Science

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Polycationic Nanofibers for Nucleic Acid Scavenging

(2016) Jennifer G. Jackman et al.   BIOMACROMOLECULES

Inflammogenesis of Secondary Spinal Cord Injury

(2016) M. Akhtar Anwar et al.   Frontiers in Cellular Neuroscience

Macrophage activation and its role in repair and pathology after spinal cord injury

(2015) John C. Gensel et al.   BRAIN RESEARCH

Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury

(2015) Y. Zhu et al.   NEUROBIOLOGY OF DISEASE

Dealing with Danger in the CNS: The Response of the Immune System to Injury

(2015) Sachin P. Gadani et al.   NEURON

Toll-like receptors in central nervous system injury and disease: A focus on the spinal cord

(2014) Adee Heiman et al.   BRAIN BEHAVIOR AND IMMUNITY

Review of transplantation of neural stem/progenitor cells for spinal cord injury

(2013) Andrea J. Mothe et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

The Therapeutic Role of Interleukin-10 after Spinal Cord Injury

(2013) Colton D. Thompson et al.   JOURNAL OF NEUROTRAUMA

Scar-mediated inhibition and CSPG receptors in the CNS

(2012) Kartavya Sharma et al.   EXPERIMENTAL NEUROLOGY

Nucleic acid-binding polymers as anti-inflammatory agents

(2011) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways

(2010) Sushil Sharma et al.   BRAIN RESEARCH

IL-10 promotes neuronal survival following spinal cord injury

(2009) Zhigang Zhou et al.   EXPERIMENTAL NEUROLOGY

Upregulation of chemokine receptor expression by IL-10/IL-4 in adult neural stem cells

(2008) Yangtai Guan et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Spinal Cord Injury Reveals Multilineage Differentiation of Ependymal Cells

(2008) Konstantinos Meletis et al.   PLOS BIOLOGY