Tissue‐Engineered Neural Network Graft Relays Excitatory Signal in the Completely Transected Canine Spinal Cord

Recovery of paralyzed limb motor function in canine with complete spinal cord injury following implantation of MSC-derived neural network tissue

(2018) Guo-Hui Wu et al.   BIOMATERIALS

Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations

(2018) Bo Chen et al.   CELL

Restorative effects of human neural stem cell grafts on the primate spinal cord

(2018) Ephron S Rosenzweig et al.   NATURE MEDICINE

NT3-chitosan enables de novo regeneration and functional recovery in monkeys after spinal cord injury

(2018) Jia-Sheng Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of an International Canine Spinal Cord Injury observational registry: a collaborative data-sharing network to optimize translational studies of SCI

(2018) Sarah A. Moore et al.   SPINAL CORD

A Modular Assembly of Spinal Cord-Like Tissue Allows Targeted Tissue Repair in the Transected Spinal Cord

(2018) Bi-Qin Lai et al.   Advanced Science

A collagen microchannel scaffold carrying paclitaxel-liposomes induces neuronal differentiation of neural stem cells through Wnt/β-catenin signaling for spinal cord injury repair

(2018) Xiaoran Li et al.   BIOMATERIALS

Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia

(2018) Megan L. Gill et al.   NATURE MEDICINE

Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury

(2018) Claudia A. Angeli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prolonged human neural stem cell maturation supports recovery in injured rodent CNS

(2017) Paul Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cell biology of spinal cord injury and repair

(2017) Timothy M. O’Shea et al.   JOURNAL OF CLINICAL INVESTIGATION

Cell transplantation therapy for spinal cord injury

(2017) Peggy Assinck et al.   NATURE NEUROSCIENCE

Defining recovery neurobiology of injured spinal cord by synthetic matrix-assisted hMSC implantation

(2017) Alexander E. Ropper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rodent, large animal and non-human primate models of spinal cord injury

(2017) Raffaele Nardone et al.   ZOOLOGY

Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum

(2017) Myeongjeong Choo et al.   Nature Communications

A Review of Stem Cell Therapy for Spinal Cord Injury: Large Animal Models and the Frontier in Humans

(2017) Brandon C. Gabel et al.   World Neurosurgery

Graft of the NT-3 persistent delivery gelatin sponge scaffold promotes axon regeneration, attenuates inflammation, and induces cell migration in rat and canine with spinal cord injury

(2016) Ge Li et al.   BIOMATERIALS

Transplantation of tissue engineering neural network and formation of neuronal relay into the transected rat spinal cord

(2016) Bi-Qin Lai et al.   BIOMATERIALS

A controlled spinal cord contusion for the rhesus macaque monkey

(2016) Zhengwen Ma et al.   EXPERIMENTAL NEUROLOGY

Neurotrophin-3 Regulates Synapse Development by Modulating TrkC-PTP  Synaptic Adhesion and Intracellular Signaling Pathways

(2016) K. A. Han et al.   JOURNAL OF NEUROSCIENCE

Organoids as an in vitro model of human development and disease

(2016) Aliya Fatehullah et al.   NATURE CELL BIOLOGY

Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration

(2016) Ken Kadoya et al.   NATURE MEDICINE

The effectiveness of 22 commonly administered physiotherapy interventions for people with spinal cord injury: a systematic review

(2016) L A Harvey et al.   SPINAL CORD

Integration of donor mesenchymal stem cell-derived neuron-like cells into host neural network after rat spinal cord transection

(2015) Xiang Zeng et al.   BIOMATERIALS

Large animal and primate models of spinal cord injury for the testing of novel therapies

(2015) Brian K. Kwon et al.   EXPERIMENTAL NEUROLOGY

Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms

(2015) Nathan A. Mundell et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neurotrophin-3 Enhances the Synaptic Organizing Function of TrkC-Protein Tyrosine Phosphatase   in Rat Hippocampal Neurons

(2015) I. Ammendrup-Johnsen et al.   JOURNAL OF NEUROSCIENCE

Schwann cell transplantation for spinal cord injury repair: its significant therapeutic potential and prospectus

(2015) Haruo Kanno et al.   REVIEWS IN THE NEUROSCIENCES

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates

(2015) Lucia Friedli et al.   Science Translational Medicine

Long-Distance Migration and Colonization of Transplanted Neural Stem Cells

(2014) Oswald Steward et al.   CELL

Axonal growth and connectivity from neural stem cell grafts in models of spinal cord injury

(2014) Paul Lu et al.   CURRENT OPINION IN NEUROBIOLOGY

Stem Cells in Canine Spinal Cord Injury – Promise for Regenerative Therapy in a Large Animal Model of Human Disease

(2014) Barbara G. McMahill et al.   Stem Cell Reviews and Reports

Promotion of neuronal differentiation of neural progenitor cells by using EGFR antibody functionalized collagen scaffolds for spinal cord injury repair

(2013) Xiaoran Li et al.   BIOMATERIALS

The integration of NSC-derived and host neural networks after rat spinal cord transection

(2013) Bi-Qin Lai et al.   BIOMATERIALS

Graft of a Tissue-Engineered Neural Scaffold Serves as a Promising Strategy to Restore Myelination after Rat Spinal Cord Transection

(2013) Bi-Qin Lai et al.   STEM CELLS AND DEVELOPMENT

Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

(2012) Paul Lu et al.   CELL

Cervicolumbar Coordination in Mammalian Quadrupedal Locomotion: Role of Spinal Thoracic Circuitry and Limb Sensory Inputs

(2012) L. Juvin et al.   JOURNAL OF NEUROSCIENCE

Intrinsically determined cell death of developing cortical interneurons

(2012) Derek G. Southwell et al.   NATURE

Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury

(2012) R. van den Brand et al.   SCIENCE

Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury

(2010) Masahiko Abematsu et al.   JOURNAL OF CLINICAL INVESTIGATION

Spinal cord injury: plasticity, regeneration and the challenge of translational drug development

(2008) Armin Blesch et al.   TRENDS IN NEUROSCIENCES