Transformable amyloid-beta mimetic peptide amphiphiles for lysosomal disruption in non-small cell lung cancer

Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo

(2020) Lu Zhang et al.   Nature Nanotechnology

Targeting self-assembly peptide for inhibiting breast tumor progression and metastasis

(2020) Shi Luo et al.   BIOMATERIALS

Tumor Receptor-Mediated In Vivo Modulation of the Morphology, Phototherapeutic Properties, and Pharmacokinetics of Smart Nanomaterials

(2020) Lu Zhang et al.   ACS Nano

pH-Responsive Self-Assemblies from the Designed Folic Acid-Modified Peptide Drug for Dual-Targeting Delivery

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Systemic Therapy for Locally Advanced and Metastatic Non–Small Cell Lung Cancer

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One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer

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Lysosomal membrane permeabilization as a cell death mechanism in cancer cells

(2018) Ana Serrano-Puebla et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Enzymatic Assemblies Disrupt Membrane and Target Endoplasmic Reticulum (ER) for Selective Cancer Cell Death

(2018) Zhaoqianqi Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 5.2018

(2018) David S. Ettinger et al.   Journal of the National Comprehensive Cancer Network

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Self-Assembling Ability Determines the Activity of Enzyme-Instructed Self-Assembly for Inhibiting Cancer Cells

(2017) Zhaoqianqi Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Salinomycin kills cancer stem cells by sequestering iron in lysosomes

(2017) Trang Thi Mai et al.   Nature Chemistry

Lysosomes as Oxidative Targets for Cancer Therapy

(2017) Rebecca F. Dielschneider et al.   Oxidative Medicine and Cellular Longevity

Mitochondria localization induced self-assembly of peptide amphiphiles for cellular dysfunction

(2017) M. T. Jeena et al.   Nature Communications

Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells

(2017) Magdalena Circu et al.   PLoS One

Hexamethylene amiloride engages a novel reactive oxygen species- and lysosome-dependent programmed necrotic mechanism to selectively target breast cancer cells

(2016) Ashley R. Rowson-Hodel et al.   CANCER LETTERS

3,3′-Dioctadecyloxacarbocyanine perchlorate (DiO) as a fluorogenic probe for measurement of critical micelle concentration

(2015) Amberlyn M. Peterson et al.   Analytical Methods

Targeting the lysosome in cancer

(2015) Shengfu Piao et al.   Annals of the New York Academy of Sciences

Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay

(2015) Sonja Aits et al.   Autophagy

Vesicular disruption of lysosomal targeting organometallic polyarginine bioconjugates

(2015) Annika Gross et al.   Metallomics

Lysosomotropic agents: impact on lysosomal membrane permeabilization and cell death

(2014) Ana M. Villamil Giraldo et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A general mechanism for intracellular toxicity of metal-containing nanoparticles

(2014) Stefania Sabella et al.   Nanoscale

Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: A quantitative method for oxidative stress assessment of nanoparticle-treated cells

(2013) A. Aranda et al.   TOXICOLOGY IN VITRO

Cancer-associated lysosomal changes: friends or foes?

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Imaging enzyme-triggered self-assembly of small molecules inside live cells

(2012) Yuan Gao et al.   Nature Communications

Disruption of Lysosome Function Promotes Tumor Growth and Metastasis inDrosophila

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Intrinsic differences in cisplatin sensitivity of head and neck cancer cell lines: Correlation to lysosomal pH

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