Microbial Rhodopsins as Multi-functional Photoreactive Membrane Proteins for Optogenetics

Partial recovery of visual function in a blind patient after optogenetic therapy

(2021) José-Alain Sahel et al.   NATURE MEDICINE

Comparative Studies of the Fluorescence Properties of Microbial Rhodopsins: Spontaneous Emission Versus Photo-Intermediate Fluorescence

(2020) Keiichi Kojima et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Green-Sensitive, Long-Lived, Step-Functional Anion Channelrhodopsin-2 Variant as a High-Potential Neural Silencing Tool

(2020) Keiichi Kojima et al.   Journal of Physical Chemistry Letters

Progress in Clinical Trials of Photodynamic Therapy for Solid Tumors and the Role of Nanomedicine

(2020) Hashem O. Alsaab et al.   Cancers

Lokiarchaeota archaeon schizorhodopsin-2 (LaSzR2) is an inward proton pump displaying a characteristic feature of acid-induced spectral blue-shift

(2020) Keiichi Kojima et al.   Scientific Reports

Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics

(2019) Yoav Adam et al.   NATURE

Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination

(2019) Taro Yamanashi et al.   Scientific Reports

The Unlimited Potential of Microbial Rhodopsins as Optical Tools

(2019) Keiichi Kojima et al.   BIOCHEMISTRY

A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

(2018) Kiryl D. Piatkevich et al.   Nature Chemical Biology

Spectroscopic characteristics of Rubricoccus marinus xenorhodopsin (RmXeR) and a putative model for its inward H+ transport mechanism

(2018) Saki Inoue et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Structural mechanisms of selectivity and gating in anion channelrhodopsins

(2018) Hideaki E. Kato et al.   NATURE

Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning

(2018) Wataru Kakegawa et al.   NEURON

A unique choanoflagellate enzyme rhodopsin exhibits light-dependent cyclic nucleotide phosphodiesterase activity

(2017) Kazuho Yoshida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Demonstration of a Light-Driven SO42– Transporter and Its Spectroscopic Characteristics

(2017) Akiko Niho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Expanding Family of Natural Anion Channelrhodopsins Reveals Large Variations in Kinetics, Conductance and Spectral Sensitivity

(2017) Elena G. Govorunova et al.   Scientific Reports

X-ray Crystallographic Structure of Thermophilic Rhodopsin

(2016) Takashi Tsukamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Memory engram storage and retrieval

(2015) Susumu Tonegawa et al.   CURRENT OPINION IN NEUROBIOLOGY

Mutant of a Light-Driven Sodium Ion Pump Can Transport Cesium Ions

(2015) Masae Konno et al.   Journal of Physical Chemistry Letters

Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

(2015) E. G. Govorunova et al.   SCIENCE

A Rhodopsin-Guanylyl Cyclase Gene Fusion Functions in Visual Perception in a Fungus

(2014) Gabriela M. Avelar et al.   CURRENT BIOLOGY

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Molecular and evolutionary aspects of microbial sensory rhodopsins

(2013) Keiichi Inoue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms

(2013) Oliver P. Ernst et al.   CHEMICAL REVIEWS

A Blue-shifted Light-driven Proton Pump for Neural Silencing

(2013) Yuki Sudo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A light-driven sodium ion pump in marine bacteria

(2013) Keiichi Inoue et al.   Nature Communications

Photo-induced Regulation of the Chromatic Adaptive Gene Expression byAnabaenaSensory Rhodopsin

(2012) Hiroki Irieda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

(2012) Linda Madisen et al.   NATURE NEUROSCIENCE

The Microbial Opsin Family of Optogenetic Tools

(2011) Feng Zhang et al.   CELL

Optical recording of action potentials in mammalian neurons using a microbial rhodopsin

(2011) Joel M Kralj et al.   NATURE METHODS

Ultra light-sensitive and fast neuronal activation with the Ca2+-permeable channelrhodopsin CatCh

(2011) Sonja Kleinlogel et al.   NATURE NEUROSCIENCE

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Engineering an Inward Proton Transport from a Bacterial Sensor Rhodopsin

(2009) Akira Kawanabe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bi-stable neural state switches

(2009) André Berndt et al.   NATURE NEUROSCIENCE